STUDIES OF OCCUPATIONAL CANCER

职业癌症的研究

• 批准号: 3752599
• 负责人: A E BLAIR
• 金额: --
• 依托单位: DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3752599
• 关键词: Chinese; Philippines; agriculture worker; bladder neoplasm; brain neoplasms; cancer risk; chemical carcinogen; chemical related neoplasm /cancer; environment related neoplasm /cancer; environmental toxicology; formaldehyde; gender difference; human mortality; human subject; human tissue; interview; lung neoplasms; meeting /conference /symposium; methylene chloride; multiple myeloma; nasopharyngeal neoplasms; neoplasm /cancer epidemiology; nonHodgkin's lymphoma; occupational disease /disorder; occupational hazard; pesticide biological effect; pesticides; racial /ethnic difference

The Occupational Studies Section conducts epidemiologic studies to identify the occupational and other causes of cancer. Analysis of mortality among farmers found excesses for several cancers among men and women, blacks and whites. Non-Hodgkin's lymphoma and multiple myeloma was excessive among farm women who applied pesticides to livestock. No clear association occurred between use of the herbicide atrazine and non- Hodgkin's lymphoma (NHL). Lung cancer was elevated among urban pesticide applicators in florida and the excess could not be accounted for by smoking. The risk of brain cancer rose with the frequency. probability and duration of occupational exposure to the solvent methylene chloride. formaldehyde was associated with the development of nasopharyngeal cancer in a case-control study from the Philippines. Contrary to earlier reports. the risk of bladder cancer among Chinese workers exposed to benzidine was lower among slow acetylators than fast acetylators. The frequency of micronuclei in lymphocytes and buccal cell increased with level of exposure to formaldehyde among a study of students in a school of mortuary science. A computerized exposure assessment system provided a method to fully document the data and procedures used in quantitative assessments in cohort studies. An international conference on cancer risks among women from occupational exposures included many new papers on this neglected topic and suggested areas for future research.

职业研究部分将流行病学研究进行 确定癌症的职业和其他原因。 分析 农民之间的死亡率发现男性中几种癌症的过剩和 妇女，黑人和白人。 非霍奇金的淋巴瘤和多发性骨髓瘤 在将农药申请牲畜的农场妇女中过度过多。 不 在使用除草剂阿雷津和非 - 霍奇金的淋巴瘤（NHL）。 城市农药中的肺癌升高 佛罗里达州的申请者和多余的人无法解释 吸烟。 脑癌的风险随着频率而增加。可能性 和职业暴露于溶剂甲基氯化物的持续时间。 甲醛与鼻咽癌的发展有关 在菲律宾的一项案例对照研究中。 与早期相反 报告。中国工人暴露于膀胱癌的风险 在慢速乙酰基剂中，苯甲胺比快速的乙酰乙基剂要低。 这 淋巴细胞和颊细胞中微核中的频率随着 在学校的学生研究中，甲醛暴露水平 太平间科学。 提供的计算机接触评估系统 一种充分记录定量中使用的数据和过程的方法 队列研究的评估。 国际癌症会议 职业暴露妇女的风险包括许多新论文 关于这个被忽视的主题，并建议未来的研究领域。