4.7 Tesla MRI Scanner Console and Gradient System

4.7 Tesla MRI 扫描仪控制台和梯度系统

• 批准号: 6877459
• 负责人: JOSEPH J. H. ACKERMAN
• 金额: $ 49.14万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6877459
• 关键词: bioimaging /biomedical imaging; biomedical equipment purchase; health science research; magnetic resonance imaging; training

DESCRIPTION (provided by applicant): This proposal from the Biomedical Magnetic Resonance Laboratory (BMRL) at Washington University in St. Louis requests funds to purchase a Varian NMR Systems MRI scanner console and a Magnex Scientific magnetic field gradient/shim system. These items will be combined with a 4.7T (200 MHz) Oxford Instruments 33-cm bore magnet, which is currently on-hand, to form a state-of-the-art MRI scanner. The scanner will be administered through the BMRL, which supports resources at the forefront of in vivo MR imaging science through its 4.7- and 11.74-T small-animal scanners located at the Medical School campus. There is a pressing need within the BMRL user community for a scanner committed to experiments that are not in vivo. These include: (i) RF coil design and testing, (ii) pulse sequence design, implementation, and validation using phantom/test objects, (iii) lengthy imaging sessions, lasting many hours or more, involving ex vivo tissue samples (e.g., heart, brain, spinal cord), and (iv) user training in scanner operation. These categories of scanner usage are critical for the ultimate success of in vivo studies and must be pursued, yet these pursuits consume scanner time that is urgently needed for in vivo experiments. The requested scanner will fill this need. Further, the scanner will be sited in the heart of the University's physics and engineering complex, enabling this physical sciences community to more effectively engage in biomedical MRI studies. This proposal provides documentation of: need, past imaging performance, organizational and training competence, and institutional commitment.

描述（由申请人提供）： 圣路易斯华盛顿大学生物医学磁共振实验室（BMRL）的提案要求资金购买Varian NMR Systems MRI Scanner控制台和Magnex Scientific Maginate Field梯度/SHIM System。这些项目将与4.7T（200 MHz）的牛津仪器33厘米的钻头相结合，目前正好形​​成最先进的MRI扫描仪。该扫描仪将通过BMRL进行管理，该扫描仪通过其在医学院校园的4.74-T小型扫描仪中支持In Vivo MR Imaging Science的最前沿的资源。在BMRL用户社区中，有迫切需要进行的扫描仪，该扫描仪致力于进行体内的实验。其中包括：（i）使用幻影/测试对象，（iii）延长的成像会话，持续数小时或更长时间，涉及过体组织样品（例如，心脏，脑，脊髓，脊髓）和（IV）在扫描仪操作中训练的脉冲序列设计，实现和验证脉冲序列设计，实现和验证。这些类别的扫描仪使用对于体内研究的最终成功至关重要，必须进行，但是这些追求消耗了体内实验所需的扫描仪时间。请求的扫描仪将满足此需求。此外，扫描仪将位于大学物理和工程综合体的中心，使这个物理科学社区能够更有效地从事生物医学MRI研究。该建议提供了：需要，过去的成像绩效，组织和培训能力以及机构承诺。