CSHL 2022 Neurodegenerative Diseases: Biology & Therapeutics Conference

CSHL 2022 神经退行性疾病：生物学

基本信息

批准号：
10539022
负责人：
DAVID J. STEWART
金额：
$ 3.08万
依托单位：
COLD SPRING HARBOR LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-08-15 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10539022
关键词：
Academia Address Alzheimer&apos s Disease Amyotrophic Lateral Sclerosis Awareness Basic Science Biological Markers Biology Businesses Cellular biology Clinical Collaborations Communities Complex Data Development Disease Disease Pathway Disease Progression Ensure Environment Faculty Feedback Fostering Future General Population Goals Government Human Individual Industrialization Industry Information Dissemination Institution International Knowledge Laboratories Lead Learning Measures Medical Methodology Methods Molecular Nationalities Nerve Degeneration Neurodegenerative Disorders Parkinson Disease Participant Pathway interactions Postdoctoral Fellow Process Public Health Questionnaires Reagent Research Research Institute Research Personnel Rights Science Scientist Societies Therapeutic Therapeutic Intervention Translational Research biopharmaceutical industry cost data exchange diagnostic strategy drug discovery forging graduate student innovation lectures lipid metabolism meetings multidisciplinary novel novel diagnostics novel therapeutics posters protein folding proteostasis reduce symptoms senior faculty social media stem success symposium therapeutically effective therapy design tool unpublished works

项目摘要

ABSTRACT Neurodegenerative Diseases: Biology & Therapeutics November 30 - December 3, 2022 This proposal seeks support for the biennial conference on Neurodegenerative Diseases: Biology & Therapeutics, from November 30 – December 3, 2022 at Cold Spring Harbor Laboratory (CSHL). The meeting brings together scientists who investigate both basic and translational aspects of neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. For many of these disorders, the molecular pathways of the disease processes remain unclear and thus few biomarkers have been identified. For other disorders, existing treatments are designed primarily to provide relief from symptoms without addressing the biology underlying degenerative processes. Translational research is therefore needed to develop and validate novel diagnostic strategies as well as new therapeutics that might halt or stem disease progression, rather than simply alleviate symptoms. The conference will advance knowledge in neurodegeneration by providing a forum where scientists from distinct laboratories and institutions, both academic and industry, can exchange findings, ideas, and seek collaborations. It will include sessions on convergent and divergent pathways in neurodegenerative diseases, glial biology, therapeutic strategies, APOE and lipid metabolism, cell biology, and protein homeostasis. For human studies seeking new treatments for neurodegeneration to be informative, it is essential for scientists who research different aspects of those treatments to meet regularly in a setting like CSHL to exchange data and ideas. The 2022 CSHL meeting on Neurodegenerative Diseases: Biology & Therapeutics will build on the successes of prior CSHL meetings to assemble an international gathering of top scientists, discuss new developments in the field, and catalyze innovative research collaborations, all of which will ultimately accelerate the pace of discovery.

抽象的神经退行性疾病：生物学与治疗学 2022年11月30日至12月3日该提案寻求两年一次的神经退行性疾病会议的支持：生物学与治疗学，2022 年 11 月 30 日至 12 月 3 日在冷泉港举行实验室（CSHL）聚集了研究基础和研究的科学家。神经退行性疾病（如阿尔茨海默病、帕金森病）的转化方面对于许多这些疾病，分子生物学。疾病过程的途径仍不清楚，因此很少有生物标志物对于已确定的其他疾病，现有的治疗方法主要是为了缓解症状。症状而不解决退化过程的生物学基础。因此需要研究来开发和验证新的诊断策略以及新的方法可能阻止或阻止疾病进展的治疗方法，而不是简单地缓解症状。该会议将通过提供一个论坛来增进神经退行性疾病的知识来自学术界和工业界不同实验室和机构的科学家可以进行交流它将包括关于趋同和分歧的会议。神经退行性疾病、神经胶质生物学、治疗策略、APOE 和脂质的通路用于寻求新疗法的人类研究。为了使神经退行性疾病具有丰富的信息，对于研究不同类型的科学家来说至关重要这些治疗的各个方面需要在 CSHL 这样的环境中定期会面，以交换数据和 2022 年 CSHL 神经退行性疾病会议：生物学与治疗学将以之前 CSHL 会议成功经验为基础，汇聚国际顶尖人士科学家，讨论该领域的新发展，并促进创新研究合作，所有这些最终都将加快发现的步伐。