CSHL 2023 Brain Barriers Conference

CSHL 2023脑障碍会议

基本信息

批准号：
10608583
负责人：
DAVID J. STEWART
金额：
$ 1.5万
依托单位：
COLD SPRING HARBOR LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-03-25 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10608583
关键词：
3-Dimensional Academia Aging Antibodies Autoimmune Diseases Biology Blood Blood - brain barrier anatomy Blood Vessels Brain COVID-19 pandemic Cells Central Nervous System Central Nervous System Agents Cerebrospinal Fluid Collaborations Communication Communities Data Development Disease Drug Delivery Systems Educational workshop Ensure Environment Faculty Female Fostering Future Goals Growth Health Human Imaging technology Immune Impairment Incentives Industrialization Industry International Knowledge Laboratories Life Maintenance Malignant Neoplasms Meningeal lymphatic system Mental disorders Methods Minority Modeling Modernization Molecular Nerve Degeneration Neurodegenerative Disorders Neurologic Nonprofit Organizations Nutrient Oral Organ Organoids Participant Peer Review Peripheral Persons Physiological Postdoctoral Fellow Prize Proteomics Publishing Research Research Institute Research Personnel STEM career Schedule Science Scientific Advances and Accomplishments Scientist Series Source Stroke Students Techniques Therapeutic Toxin Traumatic Brain Injury Woman Writing blood cerebrospinal fluid barrier career genetic technology graduate student healing imaging approach innovation interest laboratory facility lectures meetings nervous system disorder neuropathology novel strategies pharmacologic posters recruit senescence success symposium transcriptomics tumor unpublished works virtual

项目摘要

PROJECT SUMMARY Brain Barriers Cold Spring Harbor Laboratory March 28 - April 1, 2023 The proposed “Brain Barriers” meeting, to be held at the Cold Spring Harbor Laboratory (CSHL) from March 28- April 1, 2023, will assemble leaders in the fields of central nervous system (CNS) barriers, including the BBB and the blood-cerebrospinal fluid barrier, to present and discuss the latest scientific advances that will elucidate barrier function in health and disease. This application seeks support for the eighth meeting of a biennial series of CSHL meetings on this topic. Similar meetings in the field organized by other non-profit organizations have historically focused on more physiological or pharmacological aspects of the BBB. In contrast, this premiere scientific conference will emphasize modern, multi-tiered approaches spanning cellular, molecular, transcriptomic, proteomic, genetic, and imaging technologies to elucidate CNS barriers biology throughout life. CNS barrier topics to be discussed during the 2023 meeting include: (i) Emerging concepts and hot topics; (ii) Imaging approaches; (iii) Development, plasticity, and specialization; (iv) 3D and organoid CNS barrier models; (v) BBB-omics in health and disease; and (vi) Aging, senescence and neurodegeneration. Recent fundamental discoveries in CNS barriers including new knowledge regarding cell diversity and function in the human BBB, new advances in techniques to investigate barrier biology and the application of these new approaches to better understand BBB contribution to neurological diseases have set the stage for an unprecedented scientific discovery. As such, communication within the international research community is essential for fostering collaborations and fueling future advances in the field. Each session will be chaired by a pair of leading scientists at different career stages. Selected speakers will include 2-3 invited speakers as well as graduate students, postdoctoral fellows, and junior faculty selected from submitted abstracts. We have a strong emphasis on promoting junior investigators, including an entire session with platform presentations from selected young investigators and chaired by two junior faculty. One keynote lecture presented at the beginning of the meeting will provide an overview of the field and the critical background to stimulate discussion throughout the meeting. There will also be two poster sessions, one panel discussion on `Barriers to success for women and minorities in academia and industry: impact and solutions' followed by a workshop on “How to frame and write constructive and fair peer-review”. These sessions will provide support for the professional growth of all meeting attendees in particular women and minorities in STEM careers, and stimulate the scientific growth of all young scientists. Three poster prizes (1st, 2nd, and 3rd place) will be presented as late breaking short talks in the final session. The meeting has grown steadily since its inception in 2008 with a much higher virtual attendance during the COVID19 pandemic. We anticipate a meeting of moderate size (200-250 in-person participants and 150-250 virtual participants), including a high proportion of students and postdoctoral fellows.