CSHL 2023 Conference on Microbial Pathogenesis & Host Response

CSHL 2023微生物发病机制会议

• 批准号: 10675902
• 负责人: DAVID J. STEWART
• 金额: $ 0.75万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-13 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10675902
• 关键词: Amphibia; Antibiotics; Biological; Biology; COVID-19 pandemic; Cells; Cellular biology; Chiroptera; Chronic; Chronic Disease; Communicable Diseases; Communities; Development; Diagnostic; Discipline; Disease; Ecosystem; Ensure; Environment; Eukaryotic Cell; Evolution; Faculty; Genetic Diseases; Genomics; Goals; HIV; Health; Healthcare; Heart Diseases; Human; Image; Immune; Immune response; Immunocompromised Host; Immunology; Individual; Industrialization; Infection; Infection Control; Influentials; Innate Immune Response; International; Intervention; Laboratories; Learning; Malignant Neoplasms; Medical Device; Metabolic; Microbe; Microbial Antibiotic Resistance; Microbial Biofilms; Microbiology; Molecular; Molecular Genetics; Natural Immunity; Oral; Participant; Pathogenesis; Postdoctoral Fellow; Primary Infection; Recording of previous events; Regulation; Research; Research Personnel; Resistance; Role; Scientist; Surface; Technology; Time; Toxin; Ulcer; Vaccines; Visualization; War; antimicrobial; commensal microbes; dysbiosis; emerging pathogen; extensive drug resistance; genome sciences; graduate student; host-microbe interactions; human disease; human mortality; improved; insight; interdisciplinary approach; meetings; member; microbial; microbial community; microbial disease; next generation; novel; novel strategies; pandemic disease; pathogen; pathogenic bacteria; pathogenic fungus; pathogenic microbe; patient population; posters; professor; programs; skills; symposium; tool; vaccine development

Microbial Pathogenesis and Host Response September 11 – 15, 2023 ABSTRACT The fourteenth international conference on Microbial Pathogenesis and Host Response will focus on interdisciplinary approaches to study infectious disease, integrating the disciplines of molecular microbiology, eukaryotic cell biology, immunology, and genomics. Microbial diseases have once again taken an important central role in health care worldwide, due to the emergence of new pathogens, the re-ascent of common pathogens, and extensive drug resistance. Outside of human health, devastating pandemics are destabilizing ecosystems, with brown bats and amphibians currently under extreme threat. The meeting will provide an in- depth focus on the approaches that are being used to elucidate the mechanisms of bacterial and fungal pathogenesis, and promote the application of these concepts to novel strategies for the control and intervention of infectious diseases. Oral and poster sessions will focus on major emerging themes of microbial pathogenesis and the host response, including: the pathogenesis of microbial diseases; the molecular regulation of host- pathogen interactions, host cell/pathogen interaction biology, and the diversity of pathogen strategies to evade innate immunity. The sessions will integrate studies on bacterial and fungal pathogens. The oral sessions will begin with 2-3 invited talks by established leaders in the field, followed by several shorter talks chosen from submitted abstracts. Broad themes for individual sessions include: (1) role of microbial toxins and effectors in microbial diseases; (2) fundamental cell biological interactions during infection, (3) innate immune responses to microbial infection’ (4) key molecular regulation of host-microbial interactions; (5) microbial communities in health and disease, and (6) using state-of-the art technologies to visualize host-pathogen interactions. The inclusion of two poster sessions as well as the allotment of ample time for questions following each talk will encourage extensive discussion between the participants. The meeting will be small enough (250-350 scientists) to facilitate these interactions, yet large enough to allow for oral presentations not only from established investigators, but also from junior investigators and those with novel perspectives. The integration of a wide variety of aspects of bacterial and fungal pathogenesis with the host response to pathogens should promote new interdisciplinary interactions that are seldom achieved at other meetings on microbial pathogenesis that are either more narrowly focused or so diverse that the topics are challenging to integrate. The resulting interdisciplinary interactions will facilitate the development of conceptual and experimental approaches that might not otherwise be possible.

微生物发病机制和宿主反应 2023 年 9 月 11 日至 15 日 抽象的 第十四届微生物发病机制和宿主反应国际会议将重点关注 研究传染病的跨学科方法，整合分子微生物学学科， 真核细胞生物学、免疫学和基因组学再次占据重要地位。 由于新病原体的出现、常见病的重新流行，在全世界卫生保健中发挥着核心作用 除了人类健康之外，毁灭性的流行病正在破坏稳定。 生态系统，目前棕色蝙蝠和两栖动物正受到极大威胁。 深度关注用于阐明细菌和真菌机制的方法 发病机制，并促进这些概念在新的控制和干预策略中的应用 传染病的口头和海报会议将重点关注微生物发病机制的主要新兴主题。 和宿主反应，包括：微生物疾病的发病机制； 病原体相互作用、宿主细胞/病原体相互作用生物学以及病原体逃避策略的多样性 课程将整合细菌和真菌病原体的研究。 首先由该领域的知名领导者进行 2-3 次受邀演讲，然后是从以下人士中选出的几场较短的演讲： 各个会议提交的摘要包括：(1) 微生物毒素和效应物的作用。 微生物疾病；（2）感染期间的基本细胞生物学相互作用，（3）先天免疫反应 微生物感染”（4）宿主-微生物相互作用的关键分子调节；（5）健康中的微生物群落； 和疾病，以及（6）使用最先进的技术来可视化宿主与病原体的相互作用。 两次海报会议以及每次演讲后分配充足的时间提问将鼓励 会议规模足够小（250-350 名科学家）以促进与会者之间的广泛讨论。 这些互动，但足够大，不仅允许既定的研究人员进行口头陈述，而且 也来自初级研究者和那些具有新颖视角的人。 细菌和真菌的发病机制与宿主对病原体的反应应促进新的跨学科研究 在其他关于微生物发病机制的会议上很少实现的相互作用，这些会议要么更狭隘 主题集中或多样化，因此难以整合由此产生的跨学科互动。 促进概念和实验方法的发展，否则这些方法可能不可能实现。