CSHL 2019 Microbial Pathogenesis and Host Response Conference

CSHL 2019微生物发病机制与宿主反应会议

基本信息

批准号：
9761646
负责人：
DAVID J. STEWART
金额：
$ 0.7万
依托单位：
COLD SPRING HARBOR LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-01 至 2020-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9761646
关键词：
Amphibia Antibiotics Biological Biology Cells Cellular biology Chiroptera Chronic Chronic Disease Communicable Diseases Communities Development Diagnostic Discipline Disease Disease Outcome Ecology Ecosystem Ensure Environment Eukaryotic Cell Evolution Faculty Food Genetic Diseases Genomics Goals Government HIV Health Healthcare Heart Diseases Heterogeneity Human Immune Immune response Immunocompromised Host Immunology Incidence Individual Industrialization Infection Infection Control Influentials International Intervention Laboratories Learning Malignant Neoplasms Medical Device Metabolic Microbe Microbial Antibiotic Resistance Microbial Biofilms Microbiology Molecular Molecular Genetics Natural Immunity Oral Participant Pathogenesis Postdoctoral Fellow Primary Infection Recording of previous events Regulation Research Research Personnel Resistance development Role Scientist Surface Time Ulcer Vaccines Virulence War antimicrobial co-infection commensal microbes dysbiosis extensive drug resistance gastrointestinal genome sciences graduate student human disease human mortality improved insight interdisciplinary approach meetings member microbial microbial disease microbial host next generation novel novel strategies pandemic disease pathogen pathogenic bacteria pathogenic fungus pathogenic microbe patient population posters professor programs skills symposium tool vaccine development

项目摘要

Microbial Pathogenesis and Host Response September 10 - 14, 2019 The twelfth international conference on Microbial Pathogenesis and Host Response will focus on interdisciplinary approaches to study infectious disease, integrating the disciplines of molecular microbiology, eukaryotic cell biology, immunology, and genomics. Microbial diseases have once again taken an important central role in health care worldwide, due to the emergence of new pathogens, the re-ascent of common pathogens, and extensive drug resistance. Outside of human health, devastating pandemics are destabilizing ecosystems, with brown bats and amphibians currently under extreme threat. The meeting will provide an in- depth focus on the approaches that are being used to elucidate the mechanisms of bacterial and fungal pathogenesis, and promote the application of these concepts to novel strategies for the control and intervention of infectious diseases. Oral and poster sessions will focus on major emerging themes of microbial pathogenesis and the host response, including: the pathogenesis & evolution of microbial diseases; the regulation of pathogenesis, heterogeneity of pathogens as an adaptive mechanism, host cell/pathogen interactions, and the diversity of pathogen strategies to evade innate immunity. The sessions will integrate studies on bacterial and fungal pathogens. The oral sessions will begin with 2-3 invited talks by established leaders in the field, followed by several shorter talks chosen from submitted abstracts. Broad themes for individual sessions include: 1) pathogen coinfections; 2) cell biology of infections; 3) heterogeneity in pathogen and disease outcomes; 4) the diversity of pathogen evasion strategies of innate immunity; 5) microbial evolution and virulence; and 6) gastrointestinal ecology and microbial pathogenesis. The inclusion of two poster sessions as well as the allotment of ample time for questions following each talk will encourage extensive discussion between the participants. The meeting will be small enough (300 - 400 scientists) to facilitate these interactions, yet large enough to allow for oral presentations not only from established investigators, but also from junior investigators and those with novel perspectives. The integration of a wide variety of aspects of bacterial and fungal pathogenesis with the host response to pathogens should promote new interdisciplinary interactions that are seldom achieved at other meetings on microbial pathogenesis that are either more narrowly focused or so diverse that the topics are challenging to integrate. The resulting interdisciplinary interactions will facilitate the development of conceptual and experimental approaches that might not otherwise be possible.

微生物发病机制和宿主反应 2019年9月10日至14日第十二届微生物发病机制和宿主反应国际会议将重点关注研究传染病的跨学科方法，整合分子微生物学学科，真核细胞生物学、免疫学和基因组学。微生物疾病再次占据重要地位由于新病原体的出现、常见病的重新流行，在全世界卫生保健中发挥着核心作用病原体和广泛的耐药性。除了人类健康之外，毁灭性的流行病正在破坏稳定生态系统，棕色蝙蝠和两栖动物目前受到极大威胁。会议将提供一个深度关注用于阐明细菌和真菌机制的方法发病机制，并促进这些概念在控制和控制新策略中的应用传染病的干预。口头和海报会议将重点关注微生物的主要新兴主题发病机制和宿主反应，包括：微生物疾病的发病机制和进化；这发病机制的调节、作为适应性机制的病原体异质性、宿主细胞/病原体相互作用，以及病原体逃避先天免疫策略的多样性。会议将整合细菌和真菌病原体的研究。口头会议将以 2-3 名知名人士的邀请演讲开始该领域的领导者，随后是从提交的摘要中选出的几个较短的演讲。广泛的主题个别会议包括：1）病原体合并感染； 2）感染的细胞生物学； 3）病原体的异质性和疾病结果； 4）先天免疫病原体逃避策略的多样性； 5）微生物进化和毒力； 6）胃肠道生态和微生物发病机制。包含两个海报会议以及每次演讲后分配充足的时间提问将鼓励与会人员进行了广泛的讨论。会议规模足够小（300 - 400 名科学家）促进这些互动，但又足够大，不仅可以允许来自已建立的机构的口头陈述研究者，也包括初级研究者和具有新颖观点的研究者。广泛的整合细菌和真菌发病机制的各个方面与宿主对病原体的反应应促进新的跨学科互动在其他关于微生物发病机制的会议上很少实现要么关注范围更窄，要么过于多样化，以至于主题难以整合。由此产生的跨学科互动将促进概念和实验方法的发展，否则可能不可能。