CSHL 2023 Mechanisms of Metabolic Signaling Conference

CSHL 2023代谢信号机制会议

• 批准号: 10751346
• 负责人: DAVID J. STEWART
• 金额: $ 2万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-15 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10751346
• 关键词: Area; Atmosphere; Basic Science; Biochemistry; Blood Circulation; Cardiovascular Diseases; Cell Proliferation; Cells; Clinical; Clinical Research; Collaborations; Data; Dedications; Development; Diabetes Mellitus; Discipline; Disease; Disparate; Emerging Technologies; Ensure; Environment; Equity; Faculty; Family; Fostering; Future; Genome; Geography; Goals; Homeostasis; Hormones; Hybrids; Industrialization; International; Laboratories; Lead; Length of Stay; Life; Malignant Neoplasms; Mammals; Metabolic; Metabolic Control; Metabolic Diseases; Metabolic Pathway; Metabolism; Methodology; Molecular Biology; Mutation; Nutrient; Obesity; Oral; Organ; Organism; Participant; Pathway interactions; Persons; Physiology; Play; Postdoctoral Fellow; Process; Published Comment; Reagent; Regulation; Research Personnel; Role; Schedule; Scientist; Signal Transduction; System; Time; Travel; Woman; Work; cancer cell; cell type; climate change; environmental change; epigenome; field study; graduate student; innovation; insight; interest; laboratory facility; meetings; metabolic abnormality assessment; novel; pandemic disease; posters; preference; symposium; technology platform; unpublished works; virtual

Cold Spring Harbor Laboratory Conference on Mechanisms of Metabolic Signaling May 16 – 20, 2023 Project Summary This proposal seeks support for the meeting on “Mechanisms of Metabolic Signaling” to be held at Cold Spring Harbor Laboratory in May 16 - 20, 2023. The meeting will assemble leaders in the field, together with junior faculty, postdoctoral fellows and graduate students, to discuss the latest advances in our understanding of metabolic regulation and its role in normal physiology as well as a variety of disease states ranging from obesity to cancer. Metabolic processes are required for life, and are remarkably similar from organism to organism and from cell to cell. In mammals, specific cell types use metabolic pathways in highly specialized ways to conduct their cell-specific functions. Further, the specialized function of some cell types serves to maintain metabolic homeostasis of the, multicellular organism by regulating levels of hormone and metabolite messengers in the bloodstream. Metabolic diseases such as obesity and diabetes result when those processes fail. At the same time, cancer is increasingly recognized as a state whereby the malignant cell proliferates by altering its fuel metabolism and ignoring metabolic signals. The meeting will cover a broad spectrum of topics ranging from Metabolic Crosstalk with Genome and Epigenome to Interorgan Crosstalk and Nutrient Utilization. In addition, one session is dedicated to Emerging Technologies in the field. Each session will be chaired by a leading scientist in the field. Oral presentations will be given by a group of distinguished invited speakers as well as speakers selected from submitted abstracts. Selected speakers will include graduate students, postdoctoral fellows and junior faculty aiming for maximal inclusion of young investigators. Of special importance are the two poster sessions, where many participants can present their work in an atmosphere conducive to informal discussion. The meeting will be of moderate size, and we expect about 250 people to attend, the vast majority of whom will be presenting a poster or talk. Session chairs and presenters will be required to attend in-person to ensure a critical mass of attendees gathering at Cold Spring Harbor; however, we will facilitate an additional virtual audience layered on top of the in person attendance. This will be important both because travel concerns are likely to persist for some time after the pandemic, and because, looking to the future, virtual attendance at meetings will help to reduce the effects of scientific conferences on climate change and enable more equitable participation from labs around the world.

冷泉港实验室会议 代谢信号传导机制 2023 年 5 月 16 日至 20 日 项目概要 该提案寻求对“代谢信号机制”会议的支持 2023年5月16日至20日在冷泉港实验室举行。会议将召集领导 在该领域，与初级教师、博士后研究员和研究生一起讨论 我们对代谢调节及其在正常生理学中的作用的理解的最新进展 以及从肥胖到癌症等各种疾病状态。 代谢过程是生命所必需的，并且生物体之间的代谢过程惊人地相似 在哺乳动物中，特定的细胞类型以高度专业化的方式使用代谢途径。 此外，某些细胞类型的特殊功能。 通过调节多细胞生物体的水平来维持代谢稳态 血液中的激素和代谢信使代谢疾病，例如肥胖。 当这些过程失败时就会导致糖尿病。同时，癌症也越来越多。 被认为是恶性细胞通过改变其燃料代谢而增殖的状态 忽略代谢信号。 会议将涵盖广泛的主题，包括代谢串扰与基因组 和表观基因组到器官间串扰和营养利用此外，还有一个会议。 每场会议都将由一位领先的人士主持。 该领域的科学家将由一组受邀的杰出演讲者进行口头演讲。 以及从提交的摘要中选出的演讲者将包括研究生。 学生、博士后研究员和初级教师旨在最大限度地包容年轻人 特别重要的是两个海报会议，许多参与者都可以参加。 会议将在有利于非正式讨论的气氛中介绍他们的工作。 规模适中，我们预计约有 250 人参加，其中绝大多数是 展示海报或演讲将被要求亲自出席。 确保冷泉港有足够数量的聚集；但是，我们将促进 除了现场出席之外，还有更多的虚拟观众，这都很重要。 因为旅行担忧可能会在大流行结束后持续一段时间，而且因为， 展望未来，虚拟出席会议将有助于减少科学影响 关于气候变化的会议，并使世界各地的实验室能够更公平地参与 世界。