ENVIROMENTAL PHENOLS AND PHTHALATES IN SEMINAL FLUID: IMPLICATIONS FOR MALE FECUNDITY

精液中的环境酚类和邻苯二甲酸盐：对男性生育力的影响

• 批准号: 9149809
• 负责人: Kurunthachalam Kannan
• 金额: $ 29.94万
• 依托单位: WADSWORTH CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-23 至 2016-09-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9149809
• 关键词: Analytical Chemistry; Benzophenones; Calibration; Chemicals; Fertility; Human; Label; Learning; Measures; National Institute of Child Health and Human Development; Parabens; Parents; Phenols; Procedures; Process; Protocols documentation; Publishing; Quality Control; Recovery; Reproduction; Sampling; Seminal fluid; Specific qualifier value; Triclosan; bisphenol A; environmental chemical; male; mass spectrometer; phthalates; quality assurance; sperm analysis; sperm cell; urinary

The study shall utilize banked semen samples from the LIFE Study to characterize and quantify a range of non-persistent environmental chemicals. Quantification of the mixture of environmental phenols and phthalates in human seminal fluid will allow assessment of how well urinary concentrations reflect these levels, and allow NICHD to explore the relationship between chemicals present in seminal fluid, semen quality, and couple fecundity.

该研究应利用生活研究中的银行精液样本来表征和量化一系列非持久环境化学物质。 定量人类精确液中环境酚和邻苯二甲酸盐的混合物将允许评估尿液浓度反映这些水平的良好水平，并允许NICHD探索在精液，精液质量和夫妇繁殖力中存在的化学物质之间的关系。