MASDA-X--AN OPTIMIZED FLAT-PANEL DIGITAL X-RAY IMAGER

MASDA-X——优化的平板数字 X 射线成像仪

• 批准号: 2443011
• 负责人: LARRY E ANTONUK
• 金额: $ 70.93万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-07-24 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2443011
• 关键词: amorphous solid; angiography; biomedical equipment development; digital imaging; fluoroscopy; phantom model; radiation detector; silicon

This application proposes an ambitious program of research to develop a new, real-time, digital, flat-panel imaging technology based upon a Multi- element Amorphous Silicon Detector Array for X-ray imaging (MASDA-X). The radiation-resistant array will consist of a 2-dimensional, self-scanning matrix of 2500 x 2500 pixels at a pixel pitch of 100 microns giving a 25 x 25 cm square imaging area. The imager consists of an x-ray converter, the array, and the associated acquisition electronics. Such imagers offer significant potential advantages over existing technologies including: (a) digital radiographic imaging with immediate image capture and presentation at equivalent or perhaps even considerably less exposure than film-screen and CR systems: (b) real-time fluoroscopic imaging with a compact unit the size of a film-cassette and with image quality free of the effects of distortion and glare that affect x-ray image intensifier (XRII) systems; (c) exposure and dynamic range comparable to that of CR systems and large compared to film-screen systems; (d) a spatial resolution of 5 l p/mm which is superior to that of existing XRII units; and (e) low cost devices offering low-maintenance and assured quality imaging. The overall objective of this research is to determine if flat-panel technology is capable of creating imaging devices with performance comparable or superior to established technologies (eg. film-screen and CR for radiography and XRII systems for fluoroscopy). The specific aims of the research are: (l) development of the imaging system in a manner so as to optimize imaging performance separately for radiography and fluoroscopy. The optimization method will involve an iterative procedure of imager construction, performance evaluation, theoretical modeling, and design improvement; (2) creation of the acquisition electronics necessary to allow optimal signal-to-noise performance of the imager and execution of the imager studies; (3) thorough quantification of the performance of the imager through measurement of its properties including observer- independent performance variables: MTF(f), DQE(f), and NPS(f) to determine how the signal and noise properties of this imager compare to those of existing technologies; (4) execution of initial quantitative examination of the possible clinical utility of the imager through observer-dependent studies comparing the performance of the flat-panel imager to that of state-of-the-art film-screen, CR, and XRII systems employing a variety of phantoms. If the performance of flat-panel x-ray imagers can be made acceptable, their potential advantages are such that this technology could become a major radiological tool early in the 21st century with a correspondingly profound impact upon health care. The proposed research will answer the essential questions of whether imagers built from this technology offer quantitative performance comparable or superior to current established technologies and thus warrant the massive investments that will be required to bring such matters into clinical use.

该应用程序提出了一个雄心勃勃的研究计划，以开发 新的，实时，数字，平板成像技术，基于多种多样 用于X射线成像的元素无定形硅检测器阵列（MASDA-X）。 这 抗辐射阵列将由二维自扫描组成 2500 x 2500像素的矩阵在100微米的像素螺距上给出25 x 25厘米平方成像区域。 成像器由X射线转换器组成， 阵列和相关的采集电子。 这样的成像器提供 与现有技术相比，重要的潜在优势包括：（a） 具有直接图像捕获和呈现的数字射线照相成像 等效甚至比电影屏幕少得多 和CR系统：（b）带有紧凑单元的实时荧光影像成像 胶片板的尺寸和图像质量无效 影响X射线图像增强器（XRII）系统的失真和眩光； （c）与CR系统和大型的曝光和动态范围相当 与电影屏幕系统相比； （d）5 L p/mm的空间分辨率 比现有XRII单元的优越； （e）低成本 提供低维护和确保质量成像的设备。 总体 这项研究的目的是确定平板技术是否是 能够创建具有性能可比性的成像设备或 优于既定技术（例如，电影屏幕和CR 荧光镜检查的X射线照相和XRII系统。 特定目标 研究是：（l）以某种方式开发成像系统 分别优化成像性能，以进行射线照相和荧光镜检查。 优化方法将涉及成像仪的迭代过程 构建，绩效评估，理论建模和设计 改进; （2）创建所需的采集电子设备 允许成像仪的最佳信噪性能和执行 成像仪研究； （3）彻底量化 图像仪通过测量其特性，包括观察者 独立性能变量：MTF（F），DQE（F）和NP（F） 该成像仪的信号和噪声特性与之相比 现有技术； （4）执行初始定量检查 图像仪可能通过观察者依赖性的临床实用性 将平板成像仪的性能与那些的性能进行比较 最先进的电影屏幕，CR和XRII系统采用了各种 幻影。 如果可以制作平板X射线成像器的性能 可以接受的是，它们的潜在优势使得这项技术可以 成为21世纪初的主要放射学工具 对医疗保健的深远影响。 拟议的研究 将回答图像器是否构建的基本问题 技术提供可比较或优越的定量性能 当前已建立的技术，因此保证大量投资 将这些问题带入临床用途需要。