Clinical Research & Patient Care Core (CRPCC)

临床研究

基本信息

批准号：
10588232
负责人：
Larry S. Schlesinger
金额：
$ 12.83万
依托单位：
TEXAS BIOMEDICAL RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-03-10 至 2027-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10588232
关键词：
Address Ambulatory Care Facilities Biomedical Research Caring Cause of Death Chest Cities Clinic Clinical Clinical Management Clinical Research Clinical Services Collection Communicable Diseases Communication Communities Complex Consultations Country Data Data Analyses Development Diabetes Mellitus Discipline Education Educational Curriculum Epidemiology Ethics Evaluation Extreme drug resistant tuberculosis Field Workers Foundations Funding Funding Agency Future Health Health Professional Homelessness Hospitals Human Subject Research Hybrids Incidence Infrastructure Inpatients Institution Knowledge Laboratories Leadership Learning Length of Stay Logistics Medical Mentors Mexican Mexico Mission Multidrug-Resistant Tuberculosis Non-Insulin-Dependent Diabetes Mellitus Oral Outpatients Participant Pathogenesis Patient Care Patients Persons Physicians Pilot Projects Population Prevention strategy Qualitative Evaluations Quantitative Evaluations Research Research Design Research Institute Research Personnel Research Training Resources Rotation Science Side Site Social Problems South Texas Specimen Specimen Handling Structure Texas Thoracic Radiography Training Treatment outcome Tuberculosis Universities Vaccines Work Writing biocontainment facility clinical care clinical center clinical research site comorbidity critical period curriculum enhancement design diagnostic strategy experience field study human old age (65+)improved interdisciplinary approach interdisciplinary curriculum interest laboratory experiment member metropolitan multidisciplinary next generation participant enrollment peer prevent programs prospective research study skills social success therapy adverse effect tool transmission process treatment strategy tuberculosis diagnostics tuberculosis treatment virtual

项目摘要

IN-TRAC Clinical Research & Patient Care Core (CRPCC) ABSTRACT Tuberculosis (TB) is a leading infectious disease cause of death worldwide. In the US, TB incidence rates are historically low, but control remains challenging in certain populations, including the communities along the US border with Mexico. Thus, there is an urgent need for the next generation of TB researchers to have an understanding of the clinical and epidemiological aspects of TB research, as a foundation for their future leadership in the development of improved TB diagnostics, surveillance, treatments and vaccines. The Clinical Research & Patient Care Core (CRPCC) of the IN-TRAC will provide to New TB Investigators (NIs) and investigators new to the TB field, the infrastructure, resources and training in TB clinical research, and education on the challenges faced by clinicians in managing TB cases. Our training sites are strategically located in south Texas, a state adjacent to Mexico, which is the number one country of origin for foreign-born TB cases in the US. The TB clinical research site is led by Dr. Restrepo, an expert in TB field epidemiology and pathogenesis in TB patients with diabetes comorbidity or old age. Her field site is unique within the US due to its access to TB patients enrolled on the Mexican side of the Texas border. The TB patient care training will be in San Antonio, led by Drs. Armitige and Seaworth, an exemplary team of physicians who are affiliated with the only free-standing TB hospital in the US, the Texas Center for Infectious Diseases (TCID). In the same setting, there are also busy outpatient clinics: The San Antonio Metropolitan Health Department Chest Clinic, and a TB regional training and medical consultation Center of Excellence (The Heartland National TB Center; HNTBC). Our Aims are to: Aim 1. Execute a personalized training curriculum on TB clinical research studies. We have designed a hybrid (hands-on and virtual) training curriculum for IN-TRAC participants on all aspects of Clinical TB Research, including ethics, study design, field logistics, data and specimen management, specimen processing and data analysis plans and communications. Aim 2. Execute a personalized training curriculum on TB patient care. IN-TRAC participants will be educated on the complex set of decisions that physicians make, particularly during the management of difficult TB cases (e.g. with DR-TB, or with social problems such as homelessness), and who require specialized management and prolonged in-hospital stays. The mentoring team will meet with each IN-TRAC participant prior to their rotation to discuss customization of the core curriculum, including the development of a pilot project, depending on the IN-TRAC participant’s interest. IN-TRAC participants will provide a written and oral evaluation of their training experience.

跟踪临床研究与患者护理核心（CRPCC）摘要结核病（TB）是全世界死亡的主要传染病。在美国，结核病的发病率是历史上很低，但在某些人群中，包括美国的社区在某些人群中仍然存在挑战与墨西哥接壤。那迫切需要下一代结核病研究人员拥有了解结核病研究的临床和流行病学方面，作为其未来的基础在改善结核病诊断，监视，治疗和疫苗的领导下。临床 TRAC的研究与患者护理核心（CRPCC）将为新的结核病研究人员（NIS）和结核病领域的新研究人员，基础设施，资源和结核病临床研究的培训以及教育关于临床医生在管理结核病病例方面面临的挑战。我们的培训网站在战略上位于南方德克萨斯州，墨西哥附近的州，这是外国出生结核病案件的第一国我们。结核病临床研究地点由TB场流行病学和发病机理的专家Restrepo领导结核病患者合并症或老年患者。她的现场网站在美国在美国的独特之处是独一无二的患者在德克萨斯州边境的墨西哥一侧入学。结核病患者护理培训将在圣安东尼奥，由博士领导。 Armitige和Seaworth是一支由唯一独立的医生组成的典范美国结核病医院，得克萨斯州传染病中心（TCID）。在同一情况下，也很忙门诊诊所：圣安东尼奥都会卫生部胸部诊所，以及结核病区域培训和卓越医疗咨询中心（Heartland National TB中心； HNTBC）。我们的目标是：目标 1。执行有关结核病临床研究的个性化培训课程。我们设计了一个混合动力车（动手和虚拟的）培训课程为临床结核病研究的各个方面培训trac参与者，包括道德，研究设计，现场登录，数据和标本管理，标本处理和数据分析计划和沟通。 AIM 2。执行有关结核病患者护理的个性化培训课程。系统中参与者将接受医生做出的复杂决定的教育，尤其是在困难的结核病案件的管理（例如，与DR-TB或无家可归的社会问题）和谁需要专门的管理并延长院内住宿。指导团队将在轮换之前与每个跟踪参与者会面，以讨论定制的核心课程，包括开发试点项目，具体取决于访问者的兴趣。牵引进程的参与者将对他们的培训经验进行书面评估和口头评估。