2023 Silk Proteins and the Transition to Biotechnologies Gordon Research Conference

2023 年丝蛋白和向生物技术的过渡戈登研究会议

• 批准号: 10681751
• 负责人: DAVID L. KAPLAN
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10681751
• 关键词: Academia; Acceleration; Address; Antibiotics; Area; Biocompatible Materials; Biological Models; Biology; Biomedical Engineering; Biotechnology; Bombyx; Chemistry; Collaborations; Development; Devices; Emerging Technologies; Engineering; Environment; Enzymes; Exhibits; Fostering; Foundations; Friends; Funding; Future; Goals; Growth Factor; Harvest; Hour; Implant; Industry; Inflammation; Inflammatory Response; Intervention; Mechanics; Medical; Medical Device; Medical Technology; Medicine; Modeling; Molecular Weight; National Institute of Biomedical Imaging and Bioengineering; Pharmaceutical Preparations; Polymers; Process; Property; Protein Family; Proteins; Regenerative Medicine; Research; Running; Schedule; Science; Silk; Spiders; Structure; Students; System; Technology; Textiles; Therapeutic; Translations; Underrepresented Populations; Variant; Virginia; Water; Woman; amphiphilicity; aqueous; biodegradable polymer; biomaterial compatibility; commercialization; copolymer; design; implanted sensor; in vivo; insight; knowledge base; materials science; meetings; multidisciplinary; novel; physical science; recruit; self assembly; symposium; tissue reconstruction; tissue regeneration; translational impact; translational potential; vaccine delivery; wearable sensor technology

Project Summary The goal of this project is to support a Gordon Research Conference on silk materials. The objective of the conference is to cover research and technologies that are emerging utilizing silk-based biomaterials and to catalyze further translational efforts in the field. The plan is to bring together experts in the field of silk science from academia and industry from around the world to focus on current advances in the understanding and utilization of this unique family of proteins from silkworms and spiders, from both fundamental and applied perspectives, and to foster collaborations with the aim to give everyone an equal platform to showcase their science and technologies. Silk Biomaterials and Engineering Platform - Developing further fundamental and translational insight into silk protein self-assembly, bioengineering, chemistry, processing and new materials engineering provides the foundation for a wide range of advances in the field of protein-based biomaterials. These insights also impact broader needs in biomaterials science and engineering, utilizing silk as a unique model polymer due to its block copolymer structure, high molecular weight amphiphilic features, and aqueous processability. These insights should inform new ideas in biomaterials science and engineering, new silk protein-based products for medical needs, and new trainees excited and informed to join the field. Medical Interventions - Impact in the field of implantable, biocompatible and fully degradable medical devices is anticipated from the discussions at the GRC. We anticipate that the information gained at the meeting should facilitate new medical impact, from vaccine delivery to tissue reconstruction and implantable and wearable sensors. The conference emphasizes diversity and women with strong representation, while providing support for inclusion of under-represented groups with funding support for attendance. We also have scheduled a GRC power hour afternoon session, which will be run by women in STEM. Broader Impact - The use of silk in medically relevant areas is timely related to the push towards sustainable technologies and green chemistry, as silk is generated in an eco-friendly manner and harvested in water for use in textiles today. The transition toward medical needs with this novel protein-based material, along with broader implications in new environmentally related applications, offers to propel new silk technologies forward; utilizing water, exploiting degradability, and meeting energy and related requirements.

项目概要 该项目的目标是支持戈登丝绸材料研究会议。的目标 会议将涵盖利用丝基生物材料新兴的研究和技术，并 促进该领域的进一步转化努力。该计划旨在汇集丝绸科学领域的专家 来自世界各地的学术界和工业界关注当前在理解和 从基础和应用角度利用来自蚕和蜘蛛的这一独特蛋白质家族 观点，并促进合作，旨在为每个人提供一个平等的平台来展示他们的 科学和技术。丝绸生物材料和工程平台 - 进一步开发基础和 对丝蛋白自组装、生物工程、化学、加工和新材料的转化洞察 工程学为蛋白质生物材料领域的广泛进步奠定了基础。 这些见解还影响生物材料科学和工程的更广泛需求，利用丝绸作为独特的材料 模型聚合物由于其嵌段共聚物结构、高分子量两亲特性和水性 可加工性。这些见解应该为生物材料科学与工程、新丝绸等领域的新想法提供信息 满足医疗需求的蛋白质产品，新学员很兴奋并得知加入该领域。医疗的 干预措施——对植入式、生物相容性和完全可降解医疗器械领域的影响 根据 GRC 的讨论预计。我们预计会议上获得的信息应该 促进新的医疗影响，从疫苗输送到组织重建以及可植入和可穿戴 传感器。会议强调多样性和具有强大代表性的女性，同时提供支持 为代表性不足的群体提供参与资金支持。我们还安排了GRC 下午的 Power Hour 会议将由 STEM 领域的女性主持。 更广泛的影响 - 在医学相关领域使用丝绸与推动可持续发展及时相关 技术和绿色化学，因为丝绸以生态友好的方式生产并在水中收获 今天在纺织品中使用。这种新型蛋白质材料向医疗需求的转变，以及 对新的环境相关应用产生更广泛的影响，推动新的丝绸技术 向前;利用水、利用可降解性以及满足能源和相关要求。