Migration to Urban Slums, Sexual Networks, and HIV in Ghana

加纳向城市贫民窟的移民、性网络和艾滋病毒

• 批准号: 8149971
• 负责人: SUSAN LYNN CASSELS
• 金额: $ 24.02万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-15 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8149971
• 关键词: AIDS prevention; Americas; Award; Behavioral; Biological Markers; Complex; Data; Data Collection; Demography; Development Plans; Discipline; Empirical Research; Epidemiology; Future; Ghana; Grant; HIV; Instruction; International; Knowledge; Mentorship; Modeling; Network-based; Nomads; Pathway Analysis; Pattern; Population; Preventive Intervention; Questionnaire Designs; Recording of previous events; Research; Research Personnel; Research Project Grants; Review Literature; Sampling; Slum; Surveys; Time; Training; Work; base; design; human migration; mathematical model; meetings; migration; sex risk; symposium; transmission process

The long-term objective of this research is to use dynamic network-based mathematical models of human migration and HIV transmission dynamics for designing and evaluating HIV prevention interventions, such as the message of concurrency. There are three specific aims of this research project. The first aim is to review existing data on migration and HIV in Ghana. This literature review and empirical research will 1) highlight migration patterns and HIV disparities in Ghana 2) emphasize gaps in our knowledge ofthe complex association between migration and HIV transmission, and 3) reveal the limitations of standard crosssectional data collection. The results of this analysis will inform the questionnaire design in the second aim. Thus the second aim of this research is to design and implement a small-scale pilot survey of sexual networks, migration history, and HIV sexual risk behaviors. The PI will also determine the feasibility of collecting HIV biomarkers for HIV for future cross-discipline work. The third aim is to develop a mathematical model based on the network sample in order to quantify the impact of migration on the spread of HIV. This pilot modeling work will be the basis of an R01 application toward the end of the ROO grant cycle.

这项研究的长期目的是使用基于动态网络的人类迁移和HIV传播动态的数学模型来设计和评估HIV预防干预措施，例如并发信息。该研究项目有三个特定的目标。第一个目的是审查有关加纳迁移和艾滋病毒的现有数据。这项文献综述和实证研究将1）突出显示 加纳的迁移模式和艾滋病毒差异2）强调我们对迁移和艾滋病毒传播之间复杂关联的知识中的差距，3）揭示了标准横截面数据收集的局限性。该分析的结果将在第二个目标中为问卷设计提供信息。 因此，这项研究的第二个目的是设计和实施对性网络，移民历史和HIV性风险行为的小规模试点调查。 PI还将确定为未来跨学科工作收集HIV的HIV生物标志物的可行性。第三个目的是基于网络样本开发数学模型，以量化迁移对HIV传播的影响。该试点建模工作将是ROO赠款周期结束时R01应用程序的基础。