Making space for HIV prevention: substance use among Latinx MSM in LA hotspots

为艾滋病毒预防创造空间：洛杉矶热点地区拉丁裔男男性接触者的药物滥用

• 批准号: 10441997
• 负责人: SUSAN LYNN CASSELS
• 金额: $ 14.87万
• 依托单位: UNIVERSITY OF CALIFORNIA SANTA BARBARA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10441997
• 关键词: AIDS prevention; Address; Administrative Supplement; COVID-19; COVID-19 pandemic; Caring; Clinical; Code; Communities; Community Developments; Community based prevention; Data; Discrimination; Epidemic; Face; Feeling; Funding; Geography; Goals; HIV; HIV Infections; HIV risk; Harm Reduction; Health; Health Personnel; Health Resources; Health care facility; Healthcare; Hospitalization; Incidence; Individual; Intervention; Interview; Knowledge; Latino; Latinx; Link; Loneliness; Mediating; Mental Health; National Institute of Drug Abuse; Outcome; Pharmacists; Population; Psychological Factors; Public Health; Reporting; Research; Respondent; Risk; Risk Factors; Risk Reduction; Sampling; Social Network; Social isolation; Unsafe Sex; Work; acceptability and feasibility; aged; black men who have sex with men; caucasian American; ethnic health disparity; health care settings; health equity; men; men who have sex with men; mortality; parent grant; peer; psychologic; psychological distress; public health intervention; racial and ethnic; racial minority; recruit; service delivery; sex; sexual minority; sexual risk behavior; social; social space; social structure; substance use; substance use prevention; transmission process

Abstract Latino men who have sex with men (MSM) comprise a community that faces elevated risk for disparately negative personal and public health outcomes, including substance use, HIV, and COVID-19 syndemics, and a commuity that remains severely underserved. We propose to examine, in-depth using qualitative interviews, the psychological factors and social spaces that may contribute to substance use and higher rates of HIV among Latinx MSM. This work will supplement our parent grant, which aims to identify and prioritize geographic HIV risk and substance use hotspots among urban, Latinx and Black men who have sex with men. Our work directly engages with issues of health equity among racial and sexual minority men, and is significant because a) targeting risk hotspots is a key priority in the “Ending the HIV Epidemic” initiative, and b) personalized public health, often occurring in different venues other than traditional health facilities within the community, is an effective way to deliver appropriate HIV prevention, care, and treatment. In this supplemental proposal, we address a potential limitation to effective differentiated service delivery, such as peer-driven harm-reduction interventions, in our HIV risk hotspots specifically among Latinx MSM; namely, would these interventions work with socially-isolated individuals who engage in substance use? To achieve our goals, we will sample 40 Latino MSM aged 18-40 who previously participated in our Activity Space research, a study that leverages the NIDA-funded mSTUDY. Our specific aims are: 1) To identify and understand how psychological health factors during COVID-19 (e.g., loneliness, psychological distress) and social network factors (e.g., social isolation, sparse social networks) activate or amplify substance use in HIV risk hotspots; and 2) To assess the acceptability and feasibility of differentiated risk- reduction interventions among Latinx MSM who use substances in the context of the COVID-19 pandemic. The goal-oriented outcome of this work will be additional knowledge on how to best prioritize risk-reduction interventions in Latinx communities outside of healthcare settings. Data will inform the development of community-based prevention and clinical interventions that incorporate key psychological issues, including unique challenges associated with the COVID-19 pandemic, and will therefore have a stronger impact among Latino MSM.

抽象的 与男性发生性关系（MSM）的拉丁裔男人组成了一个面临较高风险的社区 不同的负面个人和公共卫生结果，包括药物使用，艾滋病毒和库维德19 联合系统和通勤仍然严重欠缺。我们建议使用 定性访谈，可能有助于药物使用和的社会空间和社会空间 Latinx MSM的HIV发生率较高。这项工作将补充我们的父母赠款，该赠款旨在确定和 优先考虑具有性行为的城市，拉丁裔和黑人男性中的地理艾滋病毒风险和物质使用热点 和男人。我们的工作直接与种族和性少数群体中的健康公平问题联系在一起，并且是 意义重大，因为a）针对风险热点是“结束艾滋病毒流行”倡议的关键优先事项，b） 个性化的公共卫生，通常发生在除传统医疗机构以外的不同场所 社区是提供适当的预防艾滋病毒，护理和治疗的有效方法。在这个补充中 提案，我们解决了有效差异化服务交付的潜在限制，例如同行驱动 减少损害干预措施，在我们的HIV风险热点中，特别是在拉丁MSM中；即，这些会 干预措施与从事使用物质的社会分离的个人使用？ 为了实现我们的目标，我们将为18-40岁的40名拉丁裔MSM品尝以前参加过我们的 活动空间研究，一项利用NIDA资助的Mstudy的研究。我们的具体目的是：1） 识别并理解在Covid-19期间的心理健康因素如何（例如，孤独，心理学 遇险）和社交网络因素（例如社会隔离，稀疏社交网络）激活或放大 艾滋病毒风险热点中的药物使用； 2）评估分化风险的可接受性和可行性 - 在COVID-19大流行的背景下使用物质的Latinx MSM的减少干预措施。这 这项工作的目标结果将是有关如何最佳优先降低风险的其他知识 在医疗保健环境之外的拉丁裔社区的干预措施。数据将告知开发 基于社区的预防和临床干预措施，其中包括关键心理问题，包括 与Covid-19大流行有关的独特挑战，因此将在 拉丁裔MSM。

项目成果

Novel Location-Based Survey Using Cognitive Interviews to Assess Geographic Networks and Hotspots of Sex and Drug Use: Implementation and Validation Study.

• DOI: 10.2196/45188
• 发表时间: 2023-06-22
• 期刊: JMIR FORMATIVE RESEARCH
• 影响因子: 2.2
• 作者: Reid, Sean C.;Wang, Vania;Assaf, Ryan;Kaloper, Sofia;Murray, Alan;Shoptaw, Steven;Gorbach, Pamina;Cassels, Susan
• 通讯作者: Cassels, Susan

A call for epidemic modeling to examine historical and structural drivers of racial disparities in infectious disease.

• DOI: 10.1016/j.socscimed.2021.113833
• 发表时间: 2021-05
• 期刊: Social science & medicine (1982)
• 作者: Cassels S;Van Den Abbeele S
• 通讯作者: Van Den Abbeele S

Geographic mobility and its impact on sexual health and ongoing HIV transmission among migrant latinx men who have sex with men.

地理流动性及其对性健康的影响以及与男性发生性行为的拉丁移民男性中持续的艾滋病毒传播。

• DOI: 10.1016/j.socscimed.2022.115635
• 发表时间: 2023
• 期刊: Social science & medicine (1982)
• 作者: Cassels,Susan;Cerezo,Alison;Reid,SeanC;Rivera,DavidB;Loustalot,Colin;Meltzer,Dan
• 通讯作者: Meltzer,Dan