West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health

西弗吉尼亚州临床和转化科学研究所：全州范围内的组织，致力于打造卓越研究并吸引社区改善健康

• 批准号: 10842070
• 负责人: Sally Lynn Hodder
• 金额: $ 160.48万
• 依托单位: WEST VIRGINIA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10842070
• 关键词: 2019-nCoV; Academic Medical Centers; Acceleration; Address; Alzheimer' s Disease; Appalachian Region; Award; COVID-19 pandemic; COVID-19 patient; Cardiovascular Diseases; Categories; Chronic Disease; Chronic lung disease; Clinical; Clinical Research; Clinical Sciences; Cohort Studies; Collaborations; Color; Communication; Communities; Community Outreach; County; Development; Environmental Hazards; Exposure to; Funding; Goals; Grant; HIV; Health; Health Resources; Human; Human Resources; Incidence; Institution; Lead; Leadership; Life Expectancy; Malignant Neoplasms; Medical center; National Institute for Occupational Safety and Health; Osteopathic Medicine; Outcome; Policies; Positioning Attribute; Post-Acute Sequelae of SARS-CoV-2 Infection; Primary Care; Productivity; Public Health; Publications; Registries; Research; Research Infrastructure; Research Personnel; Rural Community; Rural Health; Rural Population; Science; Scientist; Site; Substance Use Disorder; Testing; Training; Translational Research; Trust; United States; United States Department of Veterans Affairs; United States National Institutes of Health; West Virginia; Work; addiction; cohort; community engagement; coronavirus disease; equity, diversity, and inclusion; health care service organization; health disparity; improved; medical schools; mortality; new epidemic; next generation; practice-based research network; predictive modeling; programs; reproductive; substance use; success; translational scientist

West Virginia (WV), the only state located entirely in Appalachia, has the lowest life expectancy in the nation and ranks at or near the bottom in many chronic disease categories. The WV Clinical and Translational Science Institute (WVCTSI) was created in 2012 through the initial Institutional Development Award for Clinical and Translational Research (IDeA-CTR) and successfully renewed in 2017. Over the past 9 years, WVCTSI has cultivated and nurtured a highly collaborative, statewide research infrastructure to address the substantial health disparities in WV. Over the past 4 years, WVCTSI productivity has been superb with 1,325 publications, 951 funding applications, and 688 external funding awards totaling $159.3 MM. The WVCTSI’s overarching goal for the next funding cycle is to serve as a transformational force, leading statewide clinical and translational collaborative research that positively impacts health outcomes in WV. We will achieve this goal through the following specific aims: Specific Aim 1 - Build collaborative, productive research infrastructure across WV that substantively contributes to improving WV health outcomes, Specific Aim 2 - Train and position for success the next generation of clinical and translational scientists, and Specific Aim 3 - Actively engage multiple stakeholders, including rural communities, in research and effectively disseminate research results to rural populations in a manner that facilitates understanding and trust. There are 3 important cross-cutting themes around which our efforts will be focused that include: 1) Rural Health, 2) Diversity, Equity, and Inclusion (engaging not only WV’s rural communities but also WV’s communities of color; equally important is supporting diverse investigators), and 3) the clinician scientists of tomorrow – able to frame the right questions and work to find the answers. Central to attainment of our specific aims is the highly collaborative statewide organization that WVCTSI has developed over the preceding 9 years and that now includes every major healthcare organization and academic medical center in WV, the state health department (WVDHHR), the National Institute for Occupational Safety and Health, and >100 primary care organizations across WV that constitute the WV Practice-Based Research Network. Equally important is the high level of collaboration and commitment among WVCTSI’s cores. Successful completion of our objectives will inform policy, practice, and community changes resulting in improved WV health outcomes.

西弗吉尼亚州（WV）是唯一位于阿巴拉契亚的州，在预期寿命最低 在许多慢性疾病类别中，国家和在底部或接近底部。 WV临床和 翻译科学研究所（WVCTSI）于2012年通过最初的机构创建 临床和转化研究发展奖（Idea-CTR），并成功续签 2017年。在过去的9年中，WVCTSI在全州培养和护理了高度协作 研究基础设施以解决WV中的大量健康分布。在过去的四年中， WVCTSI生产率非常出色，有1,325个出版物，951个资金申请和688 外部资金奖励总计$ 159.3毫米。 WVCTSI下一次资金的总体目标 周期将充当变革力量，领导全州临床和翻译协作 积极影响WV健康结果的研究。我们将通过以下来实现这一目标 具体目的：特定目标1-跨WV建立协作，产品研究基础架构 实质上有助于改善WV健康结果，具体目标2-火车和位置 成功的下一代临床和翻译科学家，并具体目的3-积极参与 多个利益相关者，包括粗糙社区，在研究中并有效地传播研究 结果以促进理解和信任的方式进行粗糙的人口。有3个重要 横切主题围绕我们的努力，其中包括：1）农村健康，2）多样性， 公平和包容性（不仅要吸引WV的农村社区，还吸引WV的有色社区； 同样重要的是支持潜水员的研究人员），3）明天的临床科学家 - 能够 构成正确的问题并努力寻找答案。实现我们特定目标的核心 是WVCTSI在前面的9个州开发的高度协作的全州组织 多年，现在包括WV的每个主要医疗组织和学术医疗中心， 国家卫生局（WVDHHR），美国国家职业安全与卫生研究所 >构成基于WV实践的研究网络的WV的100个初级保健组织。 同样重要的是WVCTSI核心之间的高水平协作和承诺。 成功完成我们的目标将为政策，实践和社区变化提供信息，从而 在改善的WV健康结果中。