Childhood Obesity Research Core

儿童肥胖研究核心

基本信息

批准号：
10425297
负责人：
Joyce Lee
金额：
$ 19.6万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-07-01 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10425297
关键词：
Address Adolescence Area Blood Screening Body mass index Centers for Disease Control and Prevention (U.S.)Child Childhood Chronic Disease Clinic Clinical Collaborations Collection Communities Consultations Custom Data Data Analyses Data Set Development Eating Behavior Ecosystem Electronic Health Record Etiology Funding Geography Goals Growth Growth and Development function Health Health system Hypertension Infant Infrastructure Institutional Review Boards International Intervention Intervention Studies Longitudinal cohort Maternal Health Medicine Michigan Neonatal Neonatal Screening Non-Insulin-Dependent Diabetes Mellitus Obesity Observational Study Outcome Outcomes Research Patient Outcomes Assessments Patients Policies Population Positioning Attribute Prevention Primary Health Care Productivity Provider Public Health Practice Research Research Design Research Infrastructure Research Personnel Research Support Resources Risk Factors Services Specimen Spottings System Time Translational Research Treatment outcome Universities Weight Work base behavioral health biobank cohort comparative effectiveness study data access design digital repositories evidence base fatty liver disease health care delivery health data health information technology hypercholesterolemia improved improved outcome innovation interest member novel strategies nutrition obesity in children outreach patient engagement prospective recruit repository secondary analysis social health determinants tool translational scientist trend

项目摘要

Abstract/Summary - CORC The goal of the newly proposed Childhood Obesity Research Core (CORC) is to support a robust translational research infrastructure for basic, clinical, and translational researchers focused on childhood nutrition and obesity. The CORC takes advantage of the accomplishments of Momentum Center, a university-wide and interdisciplinary childhood obesity center established in 2013, which has provided research infrastructure, funding, and outreach to childhood obesity researchers and MNORC members. The CORC addresses major barriers identified by childhood obesity investigators at the University of Michigan, related to following barriers to research: barriers with accessing electronic health record (EHR) data for research, barriers with identifying and accessing unique populations of children for observational and interventional studies, and barriers with developing health IT tools for research tasks/studies. The CORC therefore leverages the robust health information technology (IT) ecosystem at Michigan Medicine as a platform for conducting translational research embedded in the healthcare delivery system. Researchers will be provided with: (1) Access to a centralized repository of EHR data for over 200,000 children seen at Michigan Medicine between 2012 to present, and the opportunity to utilize the repository to support prospective and interventional clinical, behavioral, and health outcomes research in a longitudinal cohort of over 41,000+ children currently being seen across nine community-based primary care pediatric clinics, of whom 10,000+ have linkages to maternal health data; (2) Services to support the integration of childhood obesity research into the delivery system including the design and development of customized provider- and patient-facing health IT tools; consultation on study design, IRB, and data analysis; access to newborn screening specimens and national EHR data; and support for subject recruitment and coordinated biospecimen collection; and (3) Access to existing data and biospecimens from local and international pediatric and maternal cohorts focused on nutrition, obesity, growth, and development.

摘要/总结 - CORC 新提出的儿童肥胖研究核心（CORC）的目标是支持为基础、临床和转化研究人员提供强大的转化研究基础设施重点关注儿童营养和肥胖问题。 CORC 利用 Momentum Center 的成就，这是一个全大学范围内的跨学科儿童肥胖研究中心该中心成立于 2013 年，为儿童肥胖研究人员和 MNORC 成员。 CORC 解决了主要障碍密歇根大学儿童肥胖研究人员发现，与以下相关研究障碍：获取电子健康记录 (EHR) 数据进行研究的障碍，识别和接触独特儿童群体进行观察和获取的障碍干预研究，以及开发用于研究任务/研究的健康 IT 工具的障碍。因此，CORC 利用强大的健康信息技术 (IT) 生态系统密歇根医学作为开展转化研究的平台医疗保健提供系统。研究人员将获得： (1) 访问密歇根州超过 200,000 名儿童的 EHR 数据集中存储库 2012 年至今的医学，以及利用存储库支持的机会前瞻性和介入性临床、行为和健康结果研究目前在九个社区接受治疗的超过 41,000 名儿童的纵向队列初级保健儿科诊所，其中 10,000 多家与孕产妇健康数据有联系； (2) 支持将儿童肥胖研究纳入交付系统的服务包括设计和开发面向提供商和患者的定制健康 IT 工具；研究设计、IRB 和数据分析咨询；获取新生儿筛查标本和国家电子病历数据；以及对受试者招募和协调生物样本的支持收藏;和 (3) 获取来自当地和国际儿科和孕产妇的现有数据和生物样本队列关注营养、肥胖、生长和发育。