CSHL Conference on Mechanisms and Models of Cancer

CSHL癌症机制和模型会议

• 批准号: 7114145
• 负责人: DAVID J. STEWART
• 金额: $ 0.47万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7114145
• 关键词: disease /disorder model; meeting /conference /symposium; neoplasm /cancer; travel

DESCRIPTION (provided by applicant): Molecular alterations in tumor suppressor genes and oncogenes and their associated pathways and networks contribute in a very significant way to the development of human cancers. The last several years have seen an enormous increase in research dealing with cancer genes and their roles in growth control and various stages of tumor development. The proposed conference, in the tradition of Cold Spring Harbor meetings, will emphasize new discoveries and provide an open forum for the presentation of the latest research and results on different aspects of research on molecular mechanisms and cell and animal models of cancer. This proposal seeks support for three successive biennial meetings to be held in 2006, 2008 and 2010. The 2006 meeting will include the following topics: Cancer Signaling Pathways; Cell Cycle and Senescence; DNA Damage and Apoptosis Response; Tumor Microenvironment; Genomic Analysis and Screens; Oncogene/Tumor Suppressor Gene Networks in Tumor Development and Therapy; Rationalized Therapeutics; Animal Models of Cancer; Stem Cells and Cancer. The precise scope of the individual sessions will be decided on the basis of the openly submitted abstracts. Each session will be chaired by two established scientists in the field including the organizers, who will establish the format of each session based on the submitted abstracts. The chairs will introduce and give an overview of the topics in their sessions. Particular attention will be given to encouraging the active participation of graduate students, postdoctoral fellows and new investigators, as well as the attendance of leading scientists in the field. It is anticipated that the meeting will provide unique opportunities for the exchange of data and ideas by both junior and senior investigators in different areas of research as they apply to cancer genetics and tumor suppressor genes. Given the success of past meetings held at CSHL on this topic between 1996 and 2005, we anticipate the attendance of about 400 scientists from laboratories around the world.

描述（由申请人提供）：肿瘤抑制基因和癌基因及其相关途径和网络的分子改变对人类癌症的发展做出了非常重要的贡献。 过去几年，有关癌症基因及其在生长控制和肿瘤发展各个阶段中的作用的研究大幅增加。拟议的会议秉承冷泉港会议的传统，将强调新发现，并提供一个开放的论坛，展示癌症分子机制以及细胞和动物模型研究不同方面的最新研究和成果。 该提案寻求对将于 2006 年、2008 年和 2010 年连续召开的三届双年度会议的支持。2006 年会议将包括以下主题：癌症信号传导途径；细胞周期和衰老； DNA 损伤和细胞凋亡反应；肿瘤微环境；基因组分析和筛选；肿瘤发展和治疗中的癌基因/肿瘤抑制基因网络；合理化治疗；癌症动物模型；干细胞和癌症。 各个会议的具体范围将根据公开提交的摘要来决定。 每场会议将由包括组织者在内的该领域的两名知名科学家主持，他们将根据提交的摘要确定每场会议的格式。 主席将介绍并概述会议中的主题。 将特别关注鼓励研究生、博士后研究员和新研究人员的积极参与，以及该领域领先科学家的出席。 预计这次会议将为不同研究领域的初级和高级研究人员交流数据和想法提供独特的机会，因为它们适用于癌症遗传学和肿瘤抑制基因。 鉴于 1996 年至 2005 年间 CSHL 就该主题举行的会议取得了成功，我们预计来自世界各地实验室的约 400 名科学家将出席。