Boston University CCCR

波士顿大学CCCR

• 批准号: 10466814
• 负责人: DAVID Tobin FELSON
• 金额: $ 72.54万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-11 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10466814
• 关键词: Allied Health Profession; Area; Arthritis; Award; Behavioral Sciences; Biological; Biometry; Boston; Clinical; Clinical Research; Cohort Studies; Collaborations; Communities; Complement; Computerized Medical Record; Consensus; Consultations; Databases; Degenerative polyarthritis; Disease; Ensure; Environment; Epidemiologic Methods; Epidemiologist; Epidemiology; Europe; Evaluation; Excision; Faculty; Funding; Goals; Gout; Grant; Health; Influentials; Infusion procedures; Institutes; Institution; International; Journals; K-Series Research Career Programs; Machine Learning; Medical; Medical Research; Medical center; Methods; Musculoskeletal Diseases; Musculoskeletal Pain; New England; Osteoporosis; Outcome; Pain; Paper; Peer Review; Persons; Physical therapy; Privatization; Productivity; Public Health Schools; Publications; Publishing; Research; Research Design; Research Methodology; Research Personnel; Research Project Grants; Resources; Rheumatism; Rheumatoid Arthritis; Rheumatology; Risk Factors; Schools; Scleroderma; Spondylarthritis; Talents; Training; Translational Research; United States National Institutes of Health; Universities; Update; base; clinical center; cohort; design; epidemiology study; faculty community; faculty research; improved; innovation; interdisciplinary collaboration; mHealth; machine learning method; medical schools; meetings; member; multidisciplinary; novel; novel strategies; patient oriented; prevent; programs; protocol development; statistical service; success

OVERALL ABSTRACT The Boston University CCCR will serve as a central resource for clinical research focused mostly on the most common musculoskeletal disorders, osteoarthritis and gout and will also provide research resources for investigator based research in scleroderma, spondyloarthritis, musculoskeletal pain and osteoporosis. Center grant funding has supported 30-35 papers annually in peer reviewed journals, most in the leading arthritis journals and some in leading general medical journals. This center has trained many of the leading clinical researchers in rheumatology throughout the US and internationally, and many of these former trainees have active collaborations with the center. We will include a broad research community and a core group of faculty in this CCCR. The research community's ready access to core faculty and to the sophisticated research methods and assistance they provide will enhance the clinical and translational research of the community and will increase collaborative opportunities for the core faculty and the community. The CCCR updates BU's historical focus on epidemiologic methods to include new approaches to causal inference and adds new methods in machine learning and mobile health. The Research and Evaluation Support Core Unit (RESCU) is the focal point of this CCCR. A key feature is the weekly research (RESCU meetings in which ongoing and proposed research projects are critically evaluated. This feature ensures frequent interactions between clinician researchers, epidemiologists and biostatisticians who are the core members of the CCCR. The RESCU core unit has provided critical support for other Center grants related to rheumatic and arthritic disorders at Boston University, three current R01/U01's; five current NIH K awards (one K24, 3 K23's, one K01), an R03, an NIH trial planning grant (U34), and multiple ACR RRF awards. The overall goal of this center is to carry out and disseminate high-level clinical research informed both by state of the art clinical research methods and by clinical and biological scientific discoveries. Ultimately, we aim either to prevent the diseases we are studying or to improve the lives of those living with the diseases.

全面的 抽象的 波士顿大学CCCR将作为临床研究的核心资源，主要集中在最多 常见的肌肉骨骼疾病，骨关节炎和痛风，还将为研究资源提供研究资源 基于研究人员的硬皮病，脊椎关节炎，肌肉骨骼疼痛和骨质疏松症的研究。中心 赠款资金每年在同行评审期刊中支持30-35篇论文，其中大多数是领先的关节炎 期刊和一些领先的一般医学期刊。该中心已经培训了许多领先的临床 整个美国和国际风湿病学研究人员以及许多前学员的研究人员 与中心的积极合作。 我们将在此CCCR中包括一个广泛的研究社区和一个核心教师。研究界的 准备访问核心教师以及他们提供的复杂研究方法和协助将增强 社区的临床和翻译研究，并将增加核心的协作机会 教师和社区。 CCCR更新BU对流行病学方法的历史重点是包括新的 因果推断的方法，并添加了机器学习和移动健康方面的新方法。 研究和评估支持核心单元（RESCU）是该CCCR的焦点。一个关键功能是 每周研究（救援会议，正在进行的和拟议的研究项目进行严格评估。 此功能可确保临床研究人员，流行病学家和生物统计学家之间的频繁相互作用 谁是CCCR的核心成员。 Rescu Core单位为其他中心提供了重要的支持 波士顿大学的三个R01/U01的赠款与风湿病和关节炎疾病有关；五个当前的NIH K奖项（一个K24，3 K23，一个K01），R03，NIH审判计划赠款（U34）和多个ACR RRF奖项。 该中心的总体目标是进行并传播由州告知的高级临床研究 艺术临床研究方法以及临床和生物科学发现。最终，我们的目标是 为了防止疾病我们正在研究或改善疾病患者的生活。