Liquid phase organic transistor sensor platform based on surface sorted semiconducting carbon nanotubes for small molecules and biological targets

基于表面排序半导体碳纳米管的用于小分子和生物目标的液相有机晶体管传感器平台

• 批准号: 1101901
• 负责人: Zhenan Bao
• 金额: $ 36万
• 依托单位: Stanford University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-04-15 至 2015-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1101901&HistoricalAwards=false
• 关键词: Liquid; phase; organic; transistor; sensor

The objective of this program is to create a stable and robust electronic sensor platform capable of sensitive and selective detection of analytes in complex liquid media. This project will investigate the fabrication and functionalization strategies for sensors. This project will utilize numerous pathways of attaching receptors for small molecule and biological analytes on and around the nanotube surfaces. The approaches and methods proposed here are expected to lay the groundwork for future highly sensitive sensor technologies. The intellectual merit is to develop a technology that utilizes electrical engineering and materials science in the development of device architectures capable of functioning in complex media. The sensor platform is based on our unique solution-based method of "surface sorting" to create primarily semiconducting carbon nanotubes (scSWNTs) and our specially synthesized organic semiconductors. The project will enable a new approach to detection technology using organic electronics. The proposed studies will allow probing of biological processes as well as monitoring analyte concentrations in real time and within the required complex media. The proposed work is expected to provide a major step towards the incorporation of organic electronics within practical sensors. The broader impacts are the participation of community college students, graduate students and undergraduates, and the development of interdisciplinary research in the United States and to promote public understanding of the impact of organic electronics on industrial and economic development. The development of a highly sensitive, selective and robust sensing platform will have applications ranging from biomedical, environmental, defense to food security.

该计划的目标是创建一个稳定且强大的电子传感器平台，能够灵敏且选择性地检测复杂液体介质中的分析物。该项目将研究传感器的制造和功能化策略。该项目将利用多种途径将小分子和生物分析物的受体附着在纳米管表面及其周围。这里提出的途径和方法预计将为未来的高灵敏度传感器技术奠定基础。其智力优势是开发一种技术，利用电气工程和材料科学来开发能够在复杂介质中运行的设备架构。该传感器平台基于我们独特的基于解决方案的“表面分类”方法，主要制造半导体碳纳米管 (scSWNT) 和我们专门合成的有机半导体。该项目将实现一种使用有机电子检测技术的新方法。拟议的研究将允许探测生物过程以及实时监测所需复杂介质内的分析物浓度。拟议的工作预计将为将有机电子器件纳入实际传感器迈出重要一步。更广泛的影响是社区学院学生、研究生和本科生的参与，以及美国跨学科研究的发展，并促进公众了解有机电子对工业和经济发展的影响。高度灵敏、选择性和鲁棒性的传感平台的开发将应用于生物医学、环境、国防和食品安全等领域。