Tunneling Spectroscopy for Nanofabricated Biochemical Sensors

纳米生化传感器的隧道光谱

• 批准号: 0601269
• 负责人: Brian Willis
• 金额: $ 24万
• 依托单位: University of Delaware
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0601269&HistoricalAwards=false
• 关键词: Tunneling; Spectroscopy; Nanofabricated; Biochemical; Sensors

0601269WillisAbstractThis integrative systems proposal focuses on the science and engineering of nanofabricated molecular tunnel junctions to create novel chemical-biological sensors. The cross-departmental, interdisciplinary research program addresses the need for new concepts in low cost, portable sensing devices that can protect against environmental hazards and toxic chemical-biological agents. The research will investigate nanofabricated tunnel junctions and inelastic electron tunneling spectroscopy (IETS) for solid state sensor devices. The advantages of this work over existing concepts include: (1) sensitivity down to the single molecule level, (2) all solid state construction that allows integration into complex hybrid systems, (3) a device design that is conducive to low cost manufacturing, and (4) spectral identification of unknown molecular agents. The research will investigate a novel combination of nanofabrication techniques with atomic layer chemistry to engineer 1-2 nm spaced metal-molecule-metal tunnel junctions that will be doped with model compounds and investigated with IETS for spectral identification. The intellectual merits of the research program are the underlying science of molecular devices, including the understanding of molecule-electrode chemical interactions and charge transport through single molecule devices. In particular, there is a need for experimental data to connect physical properties and electrical measurements in single molecule tunnel junctions. IETS provides a probe of molecular structure in nanofabricated junctions that will advance the science and engineering of molecule-based devices. The broader impacts of the research program are significant for future technologies based on molecular devices that enable low cost, ubiquitous sensors that protect the public from environmental hazards and toxic chemical-biological agents. In addition, the research program will interact with the general public through a multimedia presentation to demonstrate a concrete example of nanotechnology.

0601269Willisabstractthis Integlative Systems提案侧重于纳米制造分子隧道连接的科学和工程，以创建新型的化学生物传感器。 跨部门的跨学科研究计划满足了低成本，便携式传感设备的新概念的需求，这些设备可以防止环境危害和有毒的化学生物学剂。 该研究将研究用于固态传感器设备的纳米制动隧道连接和非弹性电子隧穿光谱（IET）。 这项工作比现有概念的优点包括：（1）灵敏度降低至单分子水平，（2）所有固态结构，允许将其集成到复杂的混合系统中，（3）有助于低成本制造的设备设计，以及（4）光谱识别未知分子试剂。 该研究将研究纳米化技术与原子层化学的新型组合，以1-2 nm间隔的金属 - 金属 - 金属隧道连接处与模型化合物掺杂并与IETS进行调查，以进行光谱识别。 研究计划的智力优点是分子设备的基本科学，包括了解分子 - 电极化学相互作用和通过单分子设备的电荷传输。 特别是，需要实验数据来连接单分子隧道连接中的物理性质和电测量。 IET提供了纳米制造连接处的分子结构的探针，该连接将推进基于分子的设备的科学和工程。 该研究计划的更广泛影响对于基于分子设备的未来技术具有重要意义，该分子设备可以使低成本，无处不在的传感器保护公众免受环境危害和有毒的化学生物学剂。 此外，该研究计划将通过多媒体演示与公众互动，以展示纳米技术的具体例子。