Adjustment Problems and Substance Use in 3 Generations

第三代的适应问题和物质使用

基本信息

批准号：
9233429
负责人：
DEBORAH M. CAPALDI
金额：
$ 10万
依托单位：
OREGON SOCIAL LEARNING CENTER, INC.
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-06-20 至 2018-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9233429
关键词：
Accounting Address Adolescence Adult Age Age of Onset Alcohol abuse Alcohol consumption Alcohol dependence Alcohol or Other Drugs use Alcoholic Beverages Alcohols Awareness Behavior Biological Child Child Rearing Childhood Collection Communities Couples Data Data Analyses Data Collection Data Set Development Diagnosis Drug usage Etiology Family Fathers Feeling suicidal Generations Genetic Growth Health Impairment Individual Intervention Longitudinal Studies Marijuana Measurement Measures Modeling Mothers Nicotine Oregon Outcome Outcome Assessment Parents Pathway interactions Pattern Peer Group Prevalence Process Psychopathology Public Health Recording of previous events Reporting Risk Risk Behaviors Risk Factors Role Sample Size Sampling Severities Suicide attempt System Testing Time Tobacco Violent injury Youth alcohol measurement antisocial behavior conduct problem contextual factors cost effective critical developmental period dating violence deviant early adolescence early childhood glucuronyl glucosamine glycan sulfate intergenerational intimate partner violence marijuana use men peer peer influence prospective retention rate sex risk social suicidal behavior suicidal risk time use transmission process

项目摘要

DESCRIPTION (provided by applicant): Three Generational Study We proposes to study intergenerational transmission of alcohol, tobacco, and other drug use (ATOD) across three generations (G1, G2, and G3). We will use children in the Three Generational Study (3GS), a community sample consisting of up to two of the biological children (G3) of at-risk early adult men (G2) in the Oregon Youth Study (OYS). Multiple indicators of ATOD in G3 will be assessed, including age of onset of use and growth in use over early to midadolescence. A dynamic developmental systems approach focusing on both general pathway psychopathology and outcome-specific risk factors will be used to examine the developmental pathways of precursors (e.g., ATOD awareness) and of the emergence of these behaviors from early childhood to adolescence. Hypotheses regarding cross-generational congruence in the onset and growth of ATOD also will be examined, as well as the transmission of contextual risk and problematic behaviors across three generations, and parenting behaviors and peer influences across two generations. Additionally, the role of ATOD in the etiology of three public health problems; namely health-risking sexual behavior, suicidal thoughts and behaviors, and dating violence will be tested. The OYS men show high levels of antisocial behavior (at age 25 years, 42% had two or more arrests) and substance use (estimated 50% lifetime diagnoses for alcohol dependence or abuse and 50% prevalence of marijuana use in the mid 20s). The men are currently ages 36-38 years and, with their parents (G1), have been involved in the OYS since the G2 men were ages 9-10 years. Specific Aims will be addressed through the collection and analysis of data that will expand the sample size for the early time points (ages 3 to 11 years) and extend the study to ages 19-20 years. Additionally, we will undertake secondary data analysis of the OYS, OYS-Couples Study, and 3GS extant data sets from the beginning of the proposed study period.

描述（由申请人提供）：我们提出了三个世代的研究，以研究三代人（G1，G2和G3）的酒精，烟草和其他药物使用（ATOD）的代际传播（ATOD）。我们将在三代研究（3GS）中使用儿童，这是一个社区样本，包括俄勒冈青年研究（OYS）中最多两个生物儿童（G3）的生物儿童（G3）。将评估G3中ATOD的多个指标，包括早期至中期使用时使用的发作年龄和使用的使用年龄。一种动态的发展系统方法，重点是一般途径心理病理学和特定结果的风险因素，以检查前体的发育途径（例如ATOD意识）以及从幼儿期到青春期的这些行为的出现。还将研究有关ATOD发作和增长的跨代一致性的假设，以及在三代人之间的上下文风险和有问题的行为以及两代人之间的育儿行为和同伴影响。此外，ATOD在三个公共卫生问题的病因中的作用；即健康风险的性行为，自杀思想和行为以及约会暴力将进行测试。牡蛎男性表现出高水平的反社会行为（在25岁时，有42％的人有两次或更多的逮捕）和药物使用（估计对酒精依赖或滥用的终生诊断50％，在20年代中期使用了50％的大麻使用率）。这些男子目前年龄在36-38岁之间，与父母（G1）一起，自G2男子9-10岁以来就参与了牡蛎。将通过收集和分析数据来解决特定目标，这些数据将扩大早期时间点的样本量（3至11岁），并将研究扩展到19-20岁的年龄。此外，我们将从拟议的研究期开始，对牡蛎，牡蛎夫妇研究和3GS现有数据集进行辅助数据分析。