USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORT

南加州大学/诺里斯综合癌症中心（核心）支持

• 批准号: 7919692
• 负责人: PETER A JONES
• 金额: $ 7.42万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7919692
• 关键词: Area; California; Cancer Center; Cancer Center Support Grant; Cancer Control Research; Cancer Hospital; Comprehensive Cancer Center; Country; Development; Developmental Therapeutics Program; Direct Costs; Epigenetic Process; Evaluation; Funding; Grant; Head; Hematologic Neoplasms; Interdisciplinary Study; Leadership; Malignant Neoplasms; Malignant neoplasm of gastrointestinal tract; Molecular Genetics; Peer Review; Prevention education; Recruitment Activity; Regulation; Research; Research Infrastructure; Research Peer Review; Research Personnel; Resource Sharing; Resources; Translating; Translational Research; USC/Norris Comprehensive Cancer Center and Hospital; Universities; Urogenital Cancer; Viral; Wages; Woman; anticancer research; cancer epidemiology; member; population based; programs; tumor

DESCRIPTION (provided by applicant): The USC/Norris Comprehensive Cancer Center at the University of Southern California was founded in 1971 and has been continuously supported by a Cancer Center Core Support Grant since 1973. It has developed into a major regional and national resource for cancer research, treatment, prevention and education. Center facilities have been built and developed with support from the NCI, the University and the Kenneth Morris Jr. Cancer Hospital, which is an integral part of the Cancer Center. The Center underwent a major expansion with the addition of the Norman Topping Tower in 1996 and is currently building a third facility, the Harlyne Morris Translational Research Tower. The Center's 191 members are organized into five thematic and five translational research programs, including a "bridge" program in developmental therapeutics. The thematic programs are headed by senior investigators in the fields of molecular genetics, epigenetics and regulation, tumor microenvironment, cancer epidemiology and cancer control research. The translational programs, which provide focus to our multidisciplinary research efforts, are in developmental therapeutics, genitourinary cancers, gastrointestinal cancers, women's cancers and hematologic and viral-associated malignancies. This application is for: 1) partial salary support for the Center's senior leadership, who are responsible for planning and overseeing our research efforts; 2) support for program planning and evaluation to keep the Center at the forefront of cancer research; 3) support for the administrative infrastructure of the Center; 4) partial support for the Center's 13 shared resources which facilitate the conduct of our peer-reviewed research; and 5) support for developmental funds to help us recruit new investigators in areas we have targeted for expansion. Continued funding from the Cancer Center Core Support Grant will allow us to build on our strengths in basic and population-based research and to translate our underlying expertise into strong, peer-reviewed funded research programs focused on cancers of major consequence in this country. Cancer Center members currently hold grants totaling $91 million in direct costs, with $40 million of that coming from NCI (all exclusive of the CCSG).

描述（由申请人提供）：南加州大学的USC/Norris综合癌症中心成立于1971年，自1973年以来一直受到癌症中心核心支持赠款的不断支持。它已发展为癌症研究，治疗，预防和教育的主要地区和国家资源。 在NCI，大学和肯尼思·莫里斯（Kenneth Morris Jr. Cancer Hospital）的支持下，已建立和开发了中心设施，该医院是癌症中心不可或缺的一部分。 该中心在1996年增加了Norman Topping Tower，目前正在建造第三个设施Harlyne Morris Translational Research Tower。 该中心的191名成员分为五个主题和五个转化研究计划，包括开发治疗中的“桥梁”计划。 主题计划由分子遗传学，表观遗传学和调节，肿瘤微环境，癌症流行病学和癌症控制研究领域的高级研究人员领导。 转化计划为我们的多学科研究工作提供了重点，是发育疗法，泌尿生殖器癌，胃肠道癌，妇女癌症以及血液学和病毒相关的恶性肿瘤。 该申请是：1）对该中心高级领导的部分工资支持，负责计划和监督我们的研究工作； 2）支持计划计划和评估，以使中心处于癌症研究的最前沿； 3）支持该中心的行政基础设施； 4）部分支持该中心的13个共享资源，这些资源有助于我们经过同行评审研究的行为； 5）支持发展基金，以帮助我们在我们针对扩展的领域招募新的调查员。 癌症中心核心支持补助金的持续资金将使我们能够在基础和人群的基础研究中的优势发展，并将我们的基本专业知识转化为强大的，由同行评审的资助研究计划，重点是该国重大后果的癌症。 癌症中心成员目前持有总计9100万美元的直接费用，其中4000万美元来自NCI（全部不包括CCSG）。