Administrative Core

行政核心

基本信息

批准号：
10762158
负责人：
VICTORIA L. SEEWALDT
金额：
$ 26.29万
依托单位：
BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-22 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10762158
关键词：
Address Advocate Antelopes California Catchment Area Cellular biology City of Hope Comprehensive Cancer Center Clinical Clinical Trials Collaborations Communication Communities Community Outreach Comprehensive Cancer Center County Data Development Disparity Doctor of Medicine Doctor of Philosophy Economics Ensure Environment Evaluation Farm Fostering Funding Grant Growth Incubators Individual Latina Lead Leadership Los Angeles Mentors Mentorship Mission Monitor National Cancer Institute Neighborhoods New York City Pilot Projects Policies Policy Developments Politics Principal Investigator Publications Reporting Research Research Personnel Resources Safety Science Therapeutic Time Toxicology Training Translational Research United States United States National Institutes of Health Universities Work cancer health disparity career chimeric antigen receptor T cells disparity elimination diversity and inclusion drug development education research experience frontier health disparity human subject protection meetings member minority communities next generation outreach professor programs rural area timeline

项目摘要

The Administrative Core is led by the U54’s Principal Investigators, Ernest Martinez, Ph.D. (PI, University of California, Riverside [UCR]) and Victoria Seewaldt, M.D. (PI, City of Hope Comprehensive Cancer Center [CoHCCC]). The overall mission of the Administrative Core is to facilitate the U54 UCR – CoH Comprehensive Cancer Center (CoHCCC) U54 partnership by providing high-quality scientific leadership, administrative support, and fiscal management. The Administrative core supports U54 planning, priority-setting, and implementation. The Core will support the ability of the External Advisory Board (EAB), Internal Advisory Board (IAB), and Community Advisory Board (CAB) to guide and provide advice and oversight of our U54. Our EAB members are national leaders and lead their own P20 and U54 grants focusing on eliminating disparities. EAB leaders include Robert Winn, M.D. (Massey Comprehensive Cancer Center), Laura Fejerman, Ph.D. (UC Davis), Lucio Miele, M.D. (LSU), and Melissa Simon, Ph.D. (Lurie Comprehensive Cancer Center). Our IAB members are senior leaders at both UCR and CoHCCC. IAB leaders from UCR include Dr. Kelechi Kalu, Ph.D. and Vice Provost and Professor of Political Science; Dr. Frances Sladek, Professor of Cell Biology and Toxicology. IAB leaders from CoHCCC include Steven Forman, Ph.D., CoHCCC leader of CAR-T cell therapeutics program and Beckman Therapeutic Director; Linda Malkas, Ph.D., Dean of Translational Science and External Affairs. To ensure mentorship of the next generation of U54 leaders, we include on our IAB, two early-stage investigators (ESIs) serve on our IAB, this includes Jernej Murn, Ph.D., a basic investigator from UCR and Ana Tergas, M.D., a promising clinical trialist and Latina researcher from CoHCCC. Together, we will work with the Planning and Evaluation Core (PEC) and serve as the U54’s oversight body. The IAB will meet with U54 leaders twice-year - or more frequently if needed - to provide strategic direction, policy development, and evaluation of our U54 Partnership Projects and Cores. The PEC, IAB, and EAB will perform yearly review of Full and Pilot projects and Cores. The CAB will evaluate projects and cores – particularly our Community Outreach Core and assess our ability to mentor and promote the careers of URM ESI. The EAB, IAB, and CAB will meet jointly with U54 project and core leaders to assess overall progress and ability to impact cancer health disparities and disparities in drug development and clinical trials.

行政核心由U54的主要调查员欧内斯特·马丁内斯（Ernest Martinez）博士领导。（PI，大学加利福尼亚州河滨[UCR]）和维多利亚·塞瓦尔德（Victoria Seewaldt） [COHCCC]）。行政核心的总体任务是促进U54 UCR - COH综合癌症中心（COHCCC）U54合作伙伴关系通过提供高质量的科学领导，行政支持，和财政管理。管理核心支持U54计划，优先设定和实施。核心将支持外部顾问委员会（EAB），内部顾问委员会（IAB）和社区咨询委员会（CAB）指导并提供我们U54的建议和监督。我们的EAB成员是国家领导人并领导自己的P20和U54赠款，重点是消除差距。 EAB领导者包括 Robert Winn，医学博士（Massey综合癌症中心），Laura Fejerman，博士（UC Davis），Lucio Miele，医学博士（LSU）和梅利莎·西蒙（Melissa Simon）博士（Lurie综合癌症中心）。我们的IAB成员是高级 UCR和CoHCCC的领导者。来自UCR的IAB领导者包括Kelechi Kalu博士博士。和副教务长和政治学教授；细胞生物学和毒理学教授Frances Sladek博士。 IAB领导人 COHCCC包括CAR-T细胞疗法计划和贝克曼的CoHCCC领导者Steven Forman博士治疗主任；琳达·马尔卡斯（Linda Malkas）博士，转化科学与外交事务院长。确保下一代U54领导者的遗产，我们包括IAB，两个早期研究人员（ESI）在我们的IAB上服务，其中包括Jernej Murn博士，这是UCR和Ana Tergas的基本研究员，M.D。有前途的临床试验人员和Cohccc的拉丁裔研究员。一起，我们将与计划合作，评估核心（PEC），并充当U54的监督机构。 IAB将与U54领导人见面两次 - 如果需要的话，或更频繁地 - 提供我们U54的战略方向，政策制定和评估合伙项目和核心。 PEC，IAB和EAB将每年对全面和试点项目进行审查，以及内核。 CAB将评估项目和核心 - 尤其是我们的社区外展核心和评估我们能够心理和促进URM ESI的职业。 EAB，IAB和CAB将与U54项目共同开会和核心领导者评估总体进步和影响癌症健康差异和药物差异的能力开发和临床试验。