The Role of Ethnic Racial Discrimination on the Development of Anxious Hypervigilance in Latina Youth

民族种族歧视对拉丁裔青少年焦虑过度警觉的影响

基本信息

批准号：
10752122
负责人：
Jordan Mullins
金额：
$ 3.94万
依托单位：
UNIVERSITY OF CALIFORNIA RIVERSIDE
依托单位国家：
美国
项目类别：
财政年份：
2024
资助国家：
美国
起止时间：
2024-01-01 至 2025-12-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10752122
关键词：
Address Adolescence Advocate Anxiety Anxiety Disorders Arousal Attenuated Behavior Behavioral Benign Biological Brain region Child Data Data Analyses Data Collection Daughter Development Emotional Environment Equation Ethnic Origin Exhibits Exposure to Face Family Fright Functional Magnetic Resonance Imaging Galvanic Skin Response Immigrant Immigrant family Income Individual Intervention Knowledge Latina Latinx Learning Link Longitudinal Studies Measures Mental Health Mexican Modeling Onset of illness Parents Participant Patients Prevention Probability Psychopathology Psychophysiology Psychosocial Factor Race Reporting Research Risk Role Safety Shapes Signal Transduction Sinus Arrhythmia Socialization Stimulus Surveys Testing Theoretical model Uncertainty Youth aged anxiety reduction anxiety symptoms anxious attentional bias coping daily functioning ethnic minority population experience girls hemodynamics indexing member minority children neural neural circuit neuroimaging neurophysiology perceived discrimination preadolescence prevent prospective protective effect protective factors racial discrimination respiratory response social social culture transmission process vigilance

项目摘要

Project Summary/Abstract Threat vigilance facilitates adaptive defensive responses and is advantageous in the case of real threats. However, when extreme and persistent, it can result in excessive fear and avoidance, core features of anxiety. Theoretical models of anxiety posit that hypervigilance towards threat may elicit, maintain, or even exacerbate anxiety symptoms. Indeed, relative to healthy participants, anxiety patients show greater psychophysiological responding and dysregulated neurocircuit function in many threat-anticipatory states. Whether and how such perturbations are impacted by threat-relevant psychosocial factors, such as ethnic-racial (ER) discrimination and ER socialization, is less well understood, particularly in adolescence when anxiety risk is elevated. To address this gap in knowledge, the current proposal builds on an existing longitudinal study to examine the social experiences that exacerbate anxious hypervigilance in preadolescent Latina girls aged 8-13 years, a group exhibiting high levels of untreated anxiety that is also differentially and excessively exposed to ER discrimination. The specific aims of this proposal are (1) to understand the effect of ER discrimination on behavioral and neurophysiological indices of anxious hypervigilance in Latina girls, and (2) to explore main and moderating effects of parental ER socialization on anxious hypervigilance and the association between ER discrimination and anxious hypervigilance, respectively. Anxious hypervigilance will be assessed during two task-based measures via social judgements of emotionally ambiguous face stimuli, sympathetic and parasympathetic responses, and neural activity. Child anxiety symptoms, ER discrimination, and parental ER socialization will be assessed via survey-based measures. In sum, through this project, I will explore possible longitudinal, biological, and social sequelae of ER discrimination and ER socialization, characterize parental ER socialization practices as potential protective factors, enhance my knowledge of neurophysiological and longitudinal data analysis, and contribute to culturally-informed intervention and prevention efforts aimed at reducing anxiety in minoritized youth.

项目概要/摘要威胁警惕有助于适应性防御响应，并且在真正威胁的情况下具有优势。然而，当极端和持续时，它可能会导致过度的恐惧和回避，这是焦虑的核心特征。焦虑的理论模型认为，对威胁的过度警惕可能会引发、维持甚至加剧焦虑症状。事实上，相对于健康参与者，焦虑症患者表现出更大的心理生理变化。在许多威胁预期状态下做出反应和失调的神经回路功能。是否以及如何这样扰动受到与威胁相关的心理社会因素的影响，例如种族（ER）歧视和 ER 社会化，人们不太了解，特别是在焦虑风险升高的青春期。到为了解决这一知识差距，当前的提案建立在现有的纵向研究的基础上，以审查社交经历会加剧 8-13 岁青春期前拉丁裔女孩的焦虑和过度警觉，该组表现出高度未经治疗的焦虑，并且也有差异且过度暴露于 ER 歧视。该提案的具体目标是 (1) 了解 ER 歧视对拉丁裔女孩焦虑过度警觉的行为和神经生理学指标，以及（2）探索主要和父母 ER 社会化对焦虑过度警觉的调节作用以及 ER 与焦虑之间的关系分别是歧视和焦虑过度警惕。将在两次评估期间评估焦虑过度警觉基于任务的测量，通过对情感模糊的面部刺激、同情和情感的社会判断副交感神经反应和神经活动。儿童焦虑症状、ER 歧视和父母 ER 社会化将通过基于调查的措施进行评估。总而言之，通过这个项目，我将探索可能的 ER 歧视和 ER 社会化的纵向、生物和社会后遗症是父母的特征 ER 社会化实践作为潜在的保护因素，增强了我对神经生理学和纵向数据分析，并有助于基于文化的干预和预防工作，旨在减少少数民族青少年的焦虑。