USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORT

南加州大学/诺里斯综合癌症中心（核心）支持

• 批准号: 7931719
• 负责人: PETER A JONES
• 金额: $ 118.2万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7931719
• 关键词: USC; NORRIS; COMPREHENSIVE; CANCER; CENTER

DESCRIPTION (provided by applicant): The USC/Norris Comprehensive Cancer Center at the University of Southern California was founded in 1971 and has been continuously supported by a Cancer Center Core Support Grant since 1973. It has developed into a major regional and national resource for cancer research, treatment, prevention and education. Center facilities have been built and developed with support from the NCI, the University and the Kenneth Morris Jr. Cancer Hospital, which is an integral part of the Cancer Center. The Center underwent a major expansion with the addition of the Norman Topping Tower in 1996 and is currently building a third facility, the Harlyne Morris Translational Research Tower. The Center's 191 members are organized into five thematic and five translational research programs, including a "bridge" program in developmental therapeutics. The thematic programs are headed by senior investigators in the fields of molecular genetics, epigenetics and regulation, tumor microenvironment, cancer epidemiology and cancer control research. The translational programs, which provide focus to our multidisciplinary research efforts, are in developmental therapeutics, genitourinary cancers, gastrointestinal cancers, women's cancers and hematologic and viral-associated malignancies. This application is for: 1) partial salary support for the Center's senior leadership, who are responsible for planning and overseeing our research efforts; 2) support for program planning and evaluation to keep the Center at the forefront of cancer research; 3) support for the administrative infrastructure of the Center; 4) partial support for the Center's 13 shared resources which facilitate the conduct of our peer-reviewed research; and 5) support for developmental funds to help us recruit new investigators in areas we have targeted for expansion. Continued funding from the Cancer Center Core Support Grant will allow us to build on our strengths in basic and population-based research and to translate our underlying expertise into strong, peer-reviewed funded research programs focused on cancers of major consequence in this country. Cancer Center members currently hold grants totaling $91 million in direct costs, with $40 million of that coming from NCI (all exclusive of the CCSG).

描述（由申请人提供）：南加州大学的 USC/Norris 综合癌症中心成立于 1971 年，自 1973 年以来一直得到癌症中心核心支持拨款的持续支持。它已发展成为区域和国家的主要资源癌症研究、治疗、预防和教育。 中心设施的建设和开发得到了 NCI、大学和小肯尼斯·莫里斯癌症医院的支持，该医院是癌症中心的组成部分。 该中心于 1996 年进行了重大扩建，增建了诺曼托平塔 (Norman Topping Tower)，目前正在建设第三座设施：哈林莫里斯转化研究塔 (Harlyne Morris Translational Research Tower)。 该中心的 191 名成员分为 5 个专题研究项目和 5 个转化研究项目，其中包括发育治疗学的“桥梁”项目。 专题项目由分子遗传学、表观遗传学和调控、肿瘤微环境、癌症流行病学和癌症控制研究领域的高级研究人员领导。 这些转化项目重点关注我们的多学科研究工作，涉及发育治疗、泌尿生殖系统癌症、胃肠道癌症、女性癌症以及血液和病毒相关恶性肿瘤。 本申请用于： 1) 为中心高级领导提供部分工资支持，他们负责规划和监督我们的研究工作； 2) 支持项目规划和评估，使中心保持在癌症研究的前沿； 3) 支持中心的行政基础设施； 4) 部分支持中心的 13 个共享资源，这些资源有助于我们开展同行评审研究； 5) 支持发展基金，帮助我们在目标扩展领域招募新的研究人员。 癌症中心核心支持拨款的持续资助将使我们能够增强我们在基础和基于人群的研究方面的优势，并将我们的基础专业知识转化为强大的、经过同行评审的资助研究项目，重点关注对这个国家产生重大影响的癌症。 癌症中心成员目前持有的直接费用总额为 9100 万美元，其中 4000 万美元来自 NCI（全部不包括 CCSG）。