Biostatistics and Data Management Core

生物统计和数据管理核心

• 批准号: 10084051
• 负责人: CONSTANTIN THEODORE YIANNOUTSOS
• 金额: $ 11.63万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-07 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10084051
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Africa; Archives; Biometry; Cervical; Collaborations; Collection; Computer software; Country; Data; Data Analyses; Data Collection; Databases; Derivation procedure; Development; Ensure; Epidemiology; Exercise; Grant; Health; Human Papillomavirus; Human Resources; Informatics; Institutes; Institution; International; Lead; Leadership; Link; Malignant neoplasm of cervix uteri; Manuscripts; Mentorship; Methods; Pilot Projects; Privatization; Procedures; Reporting; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Resource Sharing; Sample Size; Secure; Site; Statistical Data Interpretation; Training; Training Activity; Training and Education; Validation; Woman; Work; Writing; advanced analytics; analytical method; career development; data archive; data centers; data exchange; data literacy; data management; data quality; design; experience; experimental study; human subject protection; instrument; member; programs; research study; statistics; symposium; training opportunity; transmission process

Abstract: The Biostatistics and Data Management Core (BDMC) of the East Africa Consortium for HPV and Cervical Cancer (EACHC) is a shared resource for study design, research collaboration and the collection, management, sharing and analysis of all data generated from all constituent research projects in the Consortium. The BDMC will provide a space for research collaboration for all investigators, enable rigorous study design and offer expertise in the collection, validation, sharing and analysis of all data generated in each project. The BDMC will also facilitate the protection of human subjects by developing and deploying secure hardware and software solutions for storage and transmission of data containing private health information. In conjunction with the Developmental Core, we will offer opportunities for training and mentorship in data collection, management and analysis. The BDMC, which is embedded in the Regional Data Center of the East Africa Regional Consortium of the International Epidemiology Databases to Evaluate AIDS (IeDEA), will use its expertise with advanced analytical methods and management of data generated from multiple programs, hardware and software platforms and countries in the region to accomplish the following three inter-related Specific Aims: Specific Aim 1: Provide statistical leadership in study design, data analysis and presentation of results for all projects proposed by the Consortium. Specific Aim 2: Offer informatics and data management expertise in the collection, harmonization, validation, integration and overall management of data generated by all research projects proposed in this application. Specific Aim 3: Serve as focal point for mentorship and training in informatics, data management and analysis for all members of the Institute, build technical and research capacity in informatics and statistics and develop a culture of rigorous study design, experimentation and reproducible research. Through these efforts, the BDMC will enable a culture of openness, sharing and reproducible research by developing operating procedures for collection, management, secure storage of research data and archiving of data and analysis software and will contribute to capacity building in the region by providing training and education with respect to study design and data literacy

抽象的： HPV和宫颈联盟的生物统计学和数据管理核心（BDMC） 癌症（每个C）是研究设计，研究合作和收藏，管理， 共享和分析该财团中所有组成研究项目产生的所有数据。 BDMC 将为所有研究人员提供研究协作的空间，启用严格的研究设计并提供 在每个项目中生成的所有数据的收集，验证，共享和分析方面的专业知识。 BDMC会 还通过开发和部署安全的硬件和软件来促进对人类受试者的保护 存储和传输包含私人健康信息的解决方案。与 发展核心，我们将为数据收集，管理和 分析。 BDMC嵌入了东非地区联盟的区域数据中心 国际流行病学数据库评估艾滋病（IEDEA），将使用其高级分析的专业知识 从多个程序，硬件和软件平台以及 该地区实现以下三个相关特定目标的国家： 特定目的1：在研究设计，数据分析和结果的呈现方面提供统计领导 财团提出的项目。 特定目标2：提供信息学和数据管理专业知识，协调，验证， 本应用程序中提出的所有研究项目生成的数据的集成和总体管理。 特定目标3：作为信息学，数据管理和分析的指导和培训的焦点 对于研究所的所有成员，在信息学和统计学中建立技术和研究能力，并开发 严格的研究设计，实验和可再现研究的培养。 通过这些努力，BDMC将通过 制定收集，管理，安全存储研究数据和归档的操作程序 数据和分析软件，将通过提供培训和 关于研究设计和数据素养的教育