National NeuroAIDS Tissue Consortium Statistics and Data Coordinating Center

国家神经艾滋病组织联盟统计和数据协调中心

基本信息

批准号：
7670424
负责人：
CONSTANTIN THEODORE YIANNOUTSOS
金额：
$ 67.06万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-08-07 至 2013-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7670424
关键词：
AIDS Dementia Complex AIDS clinical trial group AIDS neuropathy Acquired Immunodeficiency Syndrome Address Advertising Affect Aging Archives Area Arts Awareness Bioinformatics Biological California Characteristics Classification Clinical Collaborations Communication Communities Contracts Correlative Study Data Data Analyses Data Base Management Data Collection Data Coordinating Center Data Reporting Databases Development Diagnostic tests Dictionary Disease Ensure Epidemiology Fostering Funding Future Goals HIV Infections Indiana Individual Information Systems Institutes Leadership Link Liquid substance Literature Los Angeles Magnetic Resonance Spectroscopy Methodology Methods Monitor Names National NeuroAids Tissue Consortium Neurologic Neurologist Operative Surgical Procedures Pathology Patients Performance Policies Positioning Attribute Principal Investigator Procedures Process Progress Reports Protocols documentation Protons Public Relations Publications Recording of previous events Research Research Activity Research Design Research Infrastructure Research Personnel Resource Allocation Resources Role Sampling Services Site Specimen Staging Structure Syndrome System Telephone Tissue Banking Tissue Banks Tissues Training Training and Education United States National Institutes of Health Universities Update Validation Voting base cohort computerized data processing data management demographics disease characteristic experience flexibility innovation meetings member neuropsychological organizational structure patient population professor programs research clinical testing statistics tissue processing web site working group

项目摘要

DESCRIPTION (provided by applicant): This application responds to RFA-MH-08-020 National NeuroAIDS Tissue Consortium (NNTC) Data Coordinating Center (DCC). We request continued funding for EMMES Corporation, the current NNTC DCC, and support for a Statistical Coordinating Center located at Indiana University. The combined structure is henceforth identified as the NNTC Statistical and Data Coordinating Center (SDCC). Indiana University and The EMMES Corporation are submitting this application jointly to exploit their complementary capabilities in statistics, epidemiology and data management, benefit from the existing comprehensive data support infrastructure created by EMMES for the NNTC and to ensure a seamless transition. We will continue to perform and expand proven DCC functions such as (1) maintaining and expanding the centralized clinical database and the specimen and data request tracking database; (2) provide a conduit of information to the public and the research community; (3) collect, process and monitor specimen requests and distribute them to NNTC sites; (4) coordinate and archive information regarding NNTC meetings, calls and activities. We will also provide scientific and statistical leadership to optimize NNTC resources and enhance the value of the longitudinal data. We will accomplish this by (1) participating in the NNTC Steering Committee and all leadership groups and help NNTC investigators in long-range planning, establish policies and procedures for the operation of the Consortium and develop research strategies based on current and future data collected in the central NNTC database; (2) propose and conduct statistical analyses and foster collaborations with Consortium and external researchers; (3) provide scientific leadership by contributing to all aspects of the research, including concept development, study design, data collection, analysis and presentation to NNTC investigators, NIH project collaborators and the research community; (4) establish the requisite procedures to anticipate and prioritize multiple projects to optimize resource allocation within the SDCC and to meet the research goals of the NNTC leadership and the NIH and (5) conduct research in statistical methodology related to central questions, including diagnostic testing and validation, longitudinal data analysis and bioinformatics research. Through these efforts, we will increase support, optimize resources, respond to new challenges and research directions and enhance the NNTC as a unique resource to the scientific community.

描述（由申请人提供）：此申请对RFA-MH-08-020国家神经辅助组织（NNTC）数据协调中心（DCC）响应。我们要求为Emmes Corporation，当前的NNTC DCC提供持续资金，并为位于印第安纳大学的统计协调中心提供支持。合并结构随后被确定为NNTC统计和数据协调中心（SDCC）。印第安纳大学和艾米斯公司（Emmes Corporation）正在共同提交此申请，以利用其在统计，流行病学和数据管理方面的补充能力，从EMMES为NNTC创建的现有综合数据支持基础架构中受益，并确保无缝过渡。我们将继续执行和扩展验证的DCC功能，例如（1）维护和扩展集中式临床数据库以及标本和数据请求跟踪数据库；（2）向公众和研究界提供信息管道；（3）收集，处理和监视标本请求并将其分配到NNTC站点；（4）协调有关NNTC会议，电话和活动的信息。我们还将提供科学和统计领导力，以优化NNTC资源并增强纵向数据的价值。我们将通过（1）参加NNTC指导委员会和所有领导力小组来实现这一目标，并帮助NNTC调查人员进行长期计划，制定财团运营的政策和程序，并根据中央NNTC数据库中收集的当前和未来数据制定研究策略；（2）提出和进行统计分析并与财团和外部研究人员进行统计分析；（3）通过为研究的各个方面做出贡献，包括概念开发，研究设计，数据收集，分析和演示，向NNTC研究人员，NIH项目合作者和研究社区提供科学领导；（4）建立必要的程序，以预测和优先考虑多个项目，以优化SDCC内的资源分配，并实现NNTC领导力和NIH的研究目标，以及（5）（5）（5）（5）在统计方法论中进行与中心问题有关的研究，包括诊断测试和验证，纵向数据分析和生物信息信息研究。通过这些努力，我们将增加支持，优化资源，应对新的挑战和研究方向，并增强NNTC作为科学界的独特资源。