Administrative Core

行政核心

• 批准号: 10700945
• 负责人: David J. Odde
• 金额: $ 23.28万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-16 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10700945
• 关键词: Acceleration; Award; Basic Science; Biomedical Engineering; Biophysics; Brain Neoplasms; Cancer Center; Cancer Prognosis; Clinic; Collaborations; Communication; Communities; Computer Models; Development; Educational workshop; Engineering; Ensure; Evaluation; Event; Faculty; Feedback; Funding; Genome engineering; Goals; Grant; Immune; Immunologist; Immunology; Immunotherapy; Institution; Knowledge; Leadership; Malignant Neoplasms; Medicine; Microbiology; Minnesota; Oncology; Problem Solving; Procedures; Program Development; Recording of previous events; Research; Research Project Grants; Scientist; T cell response; T memory cell; T-Lymphocyte; Translations; United States National Institutes of Health; Universities; Work; cell motility; clinical translation; design; experience; immunoengineering; improved; innovation; meetings; member; mouse model; physical science; pre-clinical therapy; professor; programs; therapy development; tool; tumor; tumor immunology

Abstract Integrating advanced engineering tools and approaches into immunotherapy development projects holds the potential to improve the efficiency of the pre-clinical therapy development pipeline. Developing a robust Immuno- engineering Translation Accelerator (ITA) is a strategic goal for this PPG that stands alongside the scientific goals of the Projects. The Administrative Core will provide overall leadership and administrative support to this PPG in furtherance of the PPG’s scientific goals as well as the broader goal to establish a transformational ITA. The Core will facilitate weekly meetings and semi-annual workshops, promote integration of the PPG projects, support translational activities that emerge from this PPG, and build a collaborative and innovative cancer immuno-engineering community at the University of Minnesota. The Administrative Core will be led by MPIs David Odde (Biomedical Engineer), David Masopust (Cancer Immunologist), and David Largaespada (Genome Engineer) with support from Paolo Provenzano (Biomedical Engineer), Ingunn Stromness (Cancer Immunologist), and Branden Moriarity (Genome Engineer). The work of the Administrative Core will be facilitated by Program Manager Bo Connelly. To facilitate the broad goals of this PPG, the administrative core will implement the following specific aims: Aim 1 – Provide strong and consistent leadership and management that maximizes PPG impact. Aim 2 – Evaluate and facilitate scientific progress. Aim 3 – Build a collaborative, supportive, and innovative cancer immune bioengineering community. Aim 4 – Support and accelerate clinical translational through the creation of an Immuno-Engineering Translation Accelerator (ITA).

抽象的 将先进的工程工具和方法整合到免疫疗法开发项目中 提高临床前治疗发展管道效率的潜力。开发强大的免疫 - 工程翻译加速器（ITA）是该PPG的战略目标 项目的目标。行政核心将为此提供总体领导和行政支持 PPG促进了PPG的科学目标以及建立变革型ITA的更广泛目标。 核心将最喜欢的每周会议和半年度研讨会，促进PPG项目的整合， 支持从该PPG出现的翻译活动，并建立一个协作和创新的癌症 明尼苏达大学的免疫工程社区。行政核心将由MPI领导 David Odde（生物医学工程师），David Masopust（癌症免疫学家）和David Largaespada（基因组 工程师）在Paolo Provenzano（生物医学工程师）的支持下，Ingunn Stromness（癌症） 免疫学家）和布兰登·莫拉（Branden Moriarity）（基因组工程师）。行政核心的工作将准备 由计划经理Bo Connelly。 为了促进该PPG的广泛目标，行政核心将实施以下具体目标： 目标1 - 提供强大而一致的领导和管理，以最大程度地发挥PPG影响。 目标2 - 评估和促进科学进步。 AIM 3 - 建立一个协作，支持和创新的癌症免疫工程学社区。 AIM 4 - 通过创建免疫工程翻译来支持和加速临床翻译 加速器（ITA）。