Pilot Project Program

试点项目计划

• 批准号: 10414549
• 负责人: IAN D MENG
• 金额: $ 26.03万
• 依托单位: UNIVERSITY OF NEW ENGLAND
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10414549
• 关键词: Advisory Committees; Applications Grants; Appointment; Award; Behavior; Budgets; Centers of Research Excellence; Collaborations; Core Facility; Data; Development Plans; Direct Costs; Drosophila genus; Eligibility Determination; Ensure; Environment; Extramural Activities; Faculty; Foundations; Funding; Funding Agency; Future; Gene Targeting; Goals; Grant; Guidelines; Histology; Home; Image; Individual; Injury; Institution; Lead; Letters; Maine; Medical center; Mentors; Modeling; National Institute of General Medical Sciences; New England; New Hampshire; Pain; Pain Research; Persons; Phase; Pilot Projects; Policies; Postdoctoral Fellow; Prevention; Procedures; Process; Program Development; Progress Reports; Publications; Recommendation; Research; Research Institute; Research Personnel; Research Proposals; Review Committee; Scientific Advances and Accomplishments; Seeds; Sensory; Services; Strategic Planning; Study Section; Teacher Professional Development; Therapeutic Intervention; Time; TimeLine; Training; Training Support; United States National Institutes of Health; Universities; Update; Vocational Guidance; Wages; Work; base; career; chemotherapy induced neuropathy; data submission; experience; faculty research; graduate student; gut microbiome; industry partner; inflammatory pain; innovation; meetings; novel; programs; recruit; senior faculty; symposium; voucher

The Pilot Project Program will continue to be a critical component of the COBRE, ensuring the long-term sustainability of both the Behavior Core and the Histology and Imaging Core. Sustainability of these Cores will require continued internal use, but also a strong regional user base from academic institutions and industry partners. To accomplish this, the Pilot Project Program will solicit proposals from research faculty at both UNE and its Northern New England partner institutions (Maine Medical Center Research Institute, Maine INBRE institutions, and the University of New Hampshire), increasing the external user base for the Cores. The Pilot Project Program will provide a maximum of 2-years of funding for early-stage projects to generate preliminary data that have the best chance for obtaining extramural research dollars. With the solicitation of proposals from outside of UNE, funding priorities for the Pilot Project Program will no longer be restricted to pain research but will be expanded to include any projects that utilize the COBRE research cores. Awarding of pilot project grants will be a competitive process, with new and early-stage investigators being given priority over more senior faculty, and with project innovation and research core utilization being weighed heavily. The pilot project program from COBRE Phases 1 and 2 was highly successful, funding 14 pilot projects that have so far led to 8 new grant awards (three R15, one R01, two NIH sub-awards, and two foundation grants), with an additional five grant applications still pending or in the process of revision. The Administrative Core will implement the Pilot Project Program through the following Specific Aims. Aim 1 will solicit, review, and select highly meritorious proposals for funding. Proposals will be evaluated for their scientific strength (Significance, Innovation, and Approach), as well as investigator and environment strengths. The scientific review committee will be composed of both experienced and early-stage investigators, chaired by the COBRE Program Coordinator, mirroring NIH study section procedures. A secondary review of this committee’s recommendations will be completed by the External Advisory Committee (EAC) and COBRE Director before funding decisions are made. In Aim 2, the Administrative Core will provide oversight and evaluate the progress of all pilot project awardees. Pilot Project Leaders will receive a post-award orientation from the COBRE Director, as well as budget support from the COBRE Program Manager, with projects needing to be in full compliance with all applicable NIH policies. Scientific progress will be evaluated quarterly by the mentor(s) of the Pilot Project Leader and the Administrative Core, and annually by the EAC. The Administrative Core in Aim 3 will provide Pilot Project Leaders with career and research guidance through a faculty development program that utilizes trained, formal mentor(s) for both research and career guidance, in addition to formal in-person or asynchronous faculty development sessions. As Pilot Project Leaders may be non-UNE faculty, the Administrative Core will work their home institutions to recruit mentors and ensure that our faculty development content is congruent with their home institutions.

试点项目计划将继续成为毛c的关键组成部分，以确保长期可持续性 行为核心以及组织学和成像核心既有。这些核心的可持续性将需要继续内部 使用，也是学术机构和行业合作伙伴的强大区域用户群。为此，飞行员 项目计划将征求UNE及其新英格兰北部合作伙伴的研究学院的建议 机构（缅因州医学中心研究所，缅因州INBRE机构和新罕布什尔大学）， 增加内核的外部用户群。试点项目计划最多将提供2年的资金 对于早期项目，生成初步数据，这些数据有最佳机会获得壁外研究资金。 随着来自UNE以外的提案的征集，试点项目计划的资金优先级将不再是 仅限于疼痛研究，但将扩展到包括使用毛绒研究核心的任何项目。奖励 试点项目赠款的竞争过程将是一个竞争过程，新的和早期的调查人员优先考虑更多 高级教职员工，随着项目创新和研究核心利用的重量。试点项目计划 从鞋垫第1和2阶段取得了极大的成功，为14个试点项目提供了资金，到目前为止，已获得了8个新赠款奖 （三个R15，1 r01，两个NIH副标士和两个基金会赠款），还有五个赠款申请 待处理或修订过程。行政核心将通过 遵循特定目标。 AIM 1将征求，审查并选择高度优异的建议以进行资金。建议将是 评估其科学力量（重要性，创新和方法）以及研究者和环境 优势。科学审查委员会将由经验丰富的和早期调查员组成，由 山洞计划协调员，镜像NIH研究部分程序。对该委员会的次要审查 建议将在资金之前由外部咨询委员会（EAC）和COBRE董事完成 做出决定。在AIM 2中，行政核心将提供监督并评估所有试点项目的进度 获奖者。飞行员项目领导者将获得COBRE董事的授予后介绍以及预算支持 来自Cobre计划经理，项目需要完全符合所有适用的NIH政策。 科学进步将由试点项目负责人和行政核心的心理评估， 每年通过EAC。 AIM 3中的行政核心将为飞行员项目负责人提供职业和研究 通过一项教师发展计划的指导 除了正式的面对面或异步教师发展课程外，指导。由于飞行员项目领导者可能是 非厄教师，行政核心将努力工作以招募导师，并确保我们的教职员工 开发内容与他们的家庭机构是一致的。