Pediatric Neurointensive Care and Resuscitation Research

儿科神经重症监护和复苏研究

• 批准号: 7619153
• 负责人: PATRICK M KOCHANEK
• 金额: $ 12.56万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-25 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7619153
• 关键词: Caring; Childhood; Research; Resuscitation

DESCRIPTION (provided by applicant): Pediatric Critical Care Medicine (PCCM) specialists are the front line in neurointensive care. They respond to crises in the pediatric intensive care unit, including resuscitation and treatment of children with severe traumatic brain injury (TBI) and in-hospital cardiopulmonary arrest (CA). They interact with child neurology, neurological surgery, and physical medicine and rehabilitation (PM&R) specialists in the continuum of care. Our unique postdoctoral program trains PCCM, child neurology, neurological surgery and PM&R fellows in basic and clinical research in neurointensive care and resuscitation, establishing a link between trainees and senior scientists. In this revised competitive renewal application, funds are requested to support a total of 5 positions each yr. The program is completing its 5th year and has filled every position with high-quality fellows. Three have submitted and two have acquired K awards, and 5 have acquired or are pursuing advanced degrees or certificates. They have published or in press 22 peer-reviewed papers, presented 62 abstracts, and won 8 awards. All graduates are in academic positions. The research focus is on injury mechanisms, novel therapies, and outcomes after TBI and CA. A bench-to-bedside approach supported by federally funded studies by our faculty is used. We capitalize on the unique interaction between the Safar Center for Resuscitation Research and the PCCM, child neurology, neurological surgery, and PM&R training programs at Children's Hospital of Pittsburgh and the Univ. of Pittsburgh School of Med. The director, co-director, and principal trainers (PTs) are dedicated, qualified scientists and proven educators. The research areas of each mentor ask important questions, suitable for trainee career development and hypothesis testing. We also integrate a curriculum in neurointensive care research. Graduates can formulate, execute, analyze, present and publish experiments designed to answer key questions, and are trained in grantsmanship and research integrity. They acquire the thought process/tools to study future questions. Most training takes place in the labs of the PTs via a classical apprenticeship. A didactic program in pediatric neurointensive care/research methods is also included. Each fellow chooses a PT and an expert supervising subcommittee. Training is carried out in ~50,000 sq. ft. of fully equipped lab space. Administrative/technical staff is available, as is ample case material for clinical research. Affirmative action recruitment efforts are in place.

描述（由申请人提供）：儿科重症监护医学 (PCCM) 专家是神经重症监护的第一线。他们应对儿科重症监护病房的危机，包括对患有严重创伤性脑损伤 (TBI) 和院内心肺骤停 (CA) 的儿童进行复苏和治疗。他们与儿童神经病学、神经外科以及物理医学和康复 (PM&R) 专家进行持续护理互动。我们独特的博士后项目培训 PCCM、儿童神经病学、神经外科和 PM&R 研究员进行神经重症监护和复苏的基础和临床研究，在学员和资深科学家之间建立联系。在此修订后的竞争性续签申请中，每年需要资金支持总共 5 个职位。该项目已进入第五个年头，每个职位都由高素质的研究员填补。 3 人已提交，2 人已获得 K 奖，5 人已获得或正在攻读高级学位或证书。 他们发表或出版了 22 篇同行评审论文，提交了 62 篇摘要，并获得了 8 项奖项。 所有毕业生均担任学术职务。 研究重点是 TBI 和 CA 后的损伤机制、新疗法和结果。我们使用由我们的教职员工联邦资助的研究支持的从实验室到临床的方法。我们利用 Safar 复苏研究中心与匹兹堡儿童医院和匹兹堡大学的 PCCM、儿童神经病学、神经外科以及 PM&R 培训项目之间的独特互动。匹兹堡医学院。主任、联合主任和首席培训师 (PT) 都是敬业、合格的科学家和久经考验的教育家。每位导师的研究领域都会提出重要问题，适合学员的职业发展和假设检验。我们还整合了神经重症监护研究课程。毕业生可以制定、执行、分析、展示和发表旨在回答关键问题的实验，并接受资助和研究诚信方面的培训。他们获得了研究未来问题的思维过程/工具。大多数培训都是通过传统的学徒制在 PT 的实验室中进行。还包括儿科神经重症监护/研究方法的教学计划。每个院士选出一名PT和一名专家指导小组委员会。培训在约 50,000 平方英尺设备齐全的实验室空间中进行。提供行政/技术人员，以及充足的临床研究案例材料。平权行动招聘工作已经到位。