EPIDEMIOLOGY OF BMI REBOUND

BMI反弹的流行病学

• 批准号: 7607722
• 负责人: Stephen R Daniels
• 金额: $ 6.3万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-15 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607722
• 关键词: Age; Blood Pressure; Body Composition; Body fat; Body mass index; Child; Computer Retrieval of Information on Scientific Projects Database; Development; Diet; Epidemiology; Ethnic group; Fasting; Funding; Future; Gender; Glucose; Grant; Institution; Insulin; Lead; Left Ventricular Mass; Leptin; Lipids; Lipoproteins; Obesity; Physical activity; Plasma; Purpose; Research; Research Personnel; Resources; Risk; Socioeconomic Status; Source; Time; United States National Institutes of Health; Weight Gain; cohort; improved; prevent

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to precisely determine the age of children at Body Mass Index (BMI) rebound and evaluate potential correlates of the timing of BMI rebound in a cohort of children beginning at age 3 years. Better understanding of the epidemiology of BMI rebound could lead to improved identification of children at high risk of future obesity prior to excess weight gain. Elucidation of the determinants of the timing of BMI rebound could lead to the development of strategies to prevent the development of obesity. A major objective is to evaluate the relationship of changes in BMI with changes in body composition using dual energy x-ray absorptiometry (DXA). We will examine the association of the timing of BMI rebound and the percent body fat at the time of BMI rebound with gender, ethnic group, and socioeconomic status. We will evaluate the potential determinants of the timing of BMI rebound including diet, physical activity, and parental body mass index. We will examine the relationship of the timing of BMI rebound to percent body fat, distribution of body fat, blood pressure, plasma lipid and lipoprotein concentrations, fasting insulin, glucose and leptin levels and left ventricular mass at age 7 years.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是精确确定儿童体重指数 (BMI) 反弹的年龄，并评估从 3 岁开始的儿童队列中 BMI 反弹时间的潜在相关性。更好地了解体重指数反弹的流行病学可能有助于在体重过度增加之前更好地识别未来肥胖高风险的儿童。阐明体重指数反弹时间的决定因素可能有助于制定预防肥胖发展的策略。主要目标是使用双能 X 射线吸收测定法 (DXA) 评估 BMI 变化与身体成分变化之间的关系。我们将研究 BMI 反弹的时间和 BMI 反弹时的体脂百分比与性别、种族和社会经济地位的关系。我们将评估 BMI 反弹时间的潜在决定因素，包括饮食、体力活动和父母体重指数。我们将检查 BMI 反弹时间与 7 岁时体脂百分比、体脂分布、血压、血浆脂质和脂蛋白浓度、空腹胰岛素、血糖和瘦素水平以及左心室质量的关系。