NEUROPHYSIOLOGIC ASSESSMENT OF AT-RISK NEWBORNS

高危新生儿的神经生理学评估

基本信息

批准号：
7605955
负责人：
KATHLEEN M THOMAS
金额：
$ 0.94万
依托单位：
UNIVERSITY OF MINNESOTA
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-12-01 至 2007-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7605955
关键词：
Age-Years Auditory Behavior assessment Computer Retrieval of Information on Scientific Projects Database Diabetic mother Event-Related Potentials Funding Grant Impairment Infant Institution Investigation Iron Medial Mediating Memory Newborn Infant Protocols documentation Research Research Personnel Resources Risk Sampling Source Structure Temporal Lobe Testing United States National Institutes of Health Visual fetus hypoxia memory recognition tool

Age-Years Auditory Behavior assessment Computer Retrieval of Information on Scientific Projects Database Diabetic mother Event-Related Potentials Funding Grant Impairment Infant Institution Investigation Iron Medial Mediating Memory Newborn Infant Protocols documentation Research Research Personnel Resources Risk Sampling Source Structure Temporal Lobe Testing United States National Institutes of Health Visual fetus hypoxia memory recognition tool

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项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In this protocol we propose to continue testing samples of infants born to diabetic mothers (IDMs) and healthy full-term control infants. The hypothesis under investigation is that iron deficiency with or without fetal hypoxia can selectively damage the structures in the medial temporal lobe that mediate explicit memory; thus, we predict that IDMs may be at risk for developing impairments in memory. We continue to focus on evaluating auditory and visual recognition memory in subjects from newborn through 5 years of age, using electrophysiological (event-related potentials) tools and behavioral assessments.

该副本是利用众多研究子项目之一由NIH/NCRR资助的中心赠款提供的资源。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构是对于中心，这不一定是调查员的机构。在此方案中，我们建议继续测试糖尿病母亲（IDM）和健康的完整对照婴儿出生的婴儿的样本。所研究的假设是，有或没有胎儿缺氧的铁缺乏症可以选择性地损害介导显式记忆的内侧颞叶中的结构。因此，我们预测IDM可能有发展记忆力损害的风险。我们继续专注于评估新生儿到5岁受试者的听觉和视觉识别记忆，使用电生理（事件相关的潜在）工具和行为评估。