Development and Neural Bases of Sequence Learning

序列学习的发展和神经基础

• 批准号: 6399477
• 负责人: KATHLEEN M THOMAS
• 金额: $ 12.36万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-10 至 2002-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6399477
• 关键词: brain imaging /visualization /scanning; child (0-11); child psychology; cognition; electrophysiology; functional magnetic resonance imaging; human subject; learning; memory

DESCRIPTION (provided by applicant): This revised Research Career Award application will provide the applicant with the additional training and mentoring necessary to pursue an independent career using functional neuroimaging techniques to examine issues in developmental cognitive neuroscience. The applicant is an Instructor of Psychology in Psychiatry with doctoral training in child psychology and postdoctoral training in anatomical and functional magnetic resonance imaging (MRI) techniques with children. Her work focuses on the brain bases of learning and memory skills across childhood, in particular, the development of implicit sequence learning. The current proposal seeks to build on this developmental expertise and to further the candidate's theoretical thinking in cognitive science and advanced technical skills in the area of functional MRI, and the integration of behavioral, electrophysiological and fMRI approaches to examining the neural bases of sequence learning in children. She will be mentored in the design, conduct, and analysis of behavioral and neuroimaging studies that attempt to address gaps in the literature examining the development and neural bases of implicit learning across childhood. Studies will address normative development and will include 1) development of an eye movement based sequence learning task that is appropriate for all age ranges; 2) behavioral experiments that probe the constraints of child learning systems by manipulating characteristics of the information to be learned, and 3) parallel electrophysiological and neuroimaging studies to assess the temporal and spatial dynamics of the neural systems subserving sequence learning across development. The overall purpose of the proposedstudies is to further our understanding of the neural systems underlying the development of various forms of learning and memory. Ultimately, the long-term goal of this work is to lay the critical foundation for understanding how disruptions in the development of these neural systems may give rise to developmental disorders.

描述（由申请人提供）：该修订的研究职业奖 申请将为申请人提供额外的培训和 使用职能的指导才能从事独立职业 神经影像学技术以检查发展认知问题的问题 神经科学。申请人是精神病学心理学的讲师 儿童心理学博士培训和解剖学博士后培训 与儿童的功能磁共振成像（MRI）技术。她 工作重点是整个童年的学习和记忆技巧的大脑基础， 特别是隐式序列学习的发展。电流 提案旨在以这种发展专业知识为基础，并促进 候选人在认知科学和高级技术方面的理论思维 功能MRI领域的技能和行为的整合， 电生理学和功能磁共振成像检查的方法 儿童的序列学习。她将在设计，行为和 试图解决差距的行为和神经影像学研究的分析 研究隐性学习的发展和神经基础的文献 整个童年。研究将解决规范发展，并将包括 1）开发基于眼动的序列学习任务 适合所有年龄范围； 2）探测的行为实验 通过操纵儿童学习系统的限制 要学习的信息，以及3）平行电生理学和 神经影像学研究以评估神经的时间和空间动力学 系统跨开发的序列学习。总体目的 提出的研究是进一步了解我们对神经系统的理解 在各种形式的学习和记忆的发展基础上。最终， 这项工作的长期目标是为 了解这些神经系统发展的破坏如何 引起发育障碍。