High-Voltage Compact Capacitor for Implantable Defibrillator

用于植入式除颤器的高压紧凑型电容器

基本信息

批准号：
7480846
负责人：
BADAWI M DWEIK
金额：
$ 14.92万
依托单位：
GINER, INC.
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-03-17 至 2009-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7480846
关键词：
Address Aluminum American American Heart Association Anodes Binding Cardiac Cells Characteristics Charge Collaborations Condition Defibrillators Devices Electrolytes Extravasation Health Heart Heart Arrest Hospitals Housing Implantable Defibrillators Individual Industry Investigation Life Liquid substance Manufacturer Name Methods Myocardial Infarction Numbers Paste substance Patients Phase Polymers Porosity Procedures Process Public Health Range Risk Safety Series Shapes Shunt Device Small Business Funding Mechanisms Small Business Innovation Research Grant Solid Standards of Weights and Measures Sterilization for infection control Structure Sulfuric Acids Survivors Tantalum Technology Testing Time Weight base biomaterial compatibility concept cost day design energy density improved innovation millisecond next generation novel programs prototype seal size tantalum oxide voltage

项目摘要

DESCRIPTION (provided by applicant): High voltage Compact Capacitor for Implantable Defibrillator Worldwide, sudden cardiac arrest is a major health problem. The use of Implantable Cardioverter Defibrillators (ICD) has become an increasingly accepted treatment option, one that could save thousands of heart attack patients annually. With the increase in acceptance of these devices, the drive for improvement of ICD function and materials has intensified. The overall objective of the project program is to develop a new all solid high voltage capacitor type for the next generation of implantable defibrillators. This SBIR Phase I will demonstrate a novel and inexpensive method for the manufacture of an all-solid high energy density capacitor for ICD applications with higher operating voltages and volumetric energy densities. The objective is to increase the operating voltage of the existing Giner, Inc. high-voltage all-solid electrochemical-electrolytic capacitor. This will reduce the number of required capacitors inside the ICD from four to two, reduce the ICD weight and volume by replacing liquid electrolyte with solid electrolyte, permit use of a bipolar multi-cell series design to achieve high voltages, and, eliminate any possibility of shunt currents and electrolyte leakage, thereby enhancing reliability and safety. Prototype capacitor cells will be fabricated and characterized and tested. These units will be compared to standard capacitors to assess the overall benefit of the project. Packaging strategies will be developed and identified in collaboration with an industry leader. A unit capacitor will be fabricated and operated to demonstrate concept feasibility. Phase II will extend the investigation to optimize and standardize processes and designs to a) fabricate final cell stacks, evaluate capacitor housings, encapsulation materials, and procedures, b) perform long-term stability and biocompatibility tests, and to, c) study and select sterilization and packaging options. PUBLIC HEALTH RELEVANCE The use of Implantable Cardioverter Defibrillators (ICD) has become an increasingly accepted treatment option, one that could save thousands of heart attack patients annually. There is critical need for reduced size, high energy density capacitor for the ICD. Substantial reduction in the volume and consequently weight of the capacitor inside the ICD would represent a significant product improvement ICD resulting in many advantages for the patients.

描述（由申请人提供）：用于植入式除颤器的高压紧凑型电容器在世界范围内，心脏骤停是一个主要的健康问题。植入式心脏复律除颤器 (ICD) 的使用已成为一种越来越被接受的治疗选择，每年可以挽救数千名心脏病患者的生命。随着这些设备的接受度不断提高，改进 ICD 功能和材料的动力也不断增强。该项目计划的总体目标是为下一代植入式除颤器开发一种新型全固态高压电容器。 SBIR 第一阶段将展示一种新颖且廉价的方法，用于制造具有更高工作电压和体积能量密度的 ICD 应用的全固态高能量密度电容器。目标是提高现有 Giner, Inc. 高压全固态电化学电解电容器的工作电压。这会将 ICD 内所需的电容器数量从四个减少到两个，通过用固体电解质代替液体电解质来减少 ICD 的重量和体积，允许使用双极多电池串联设计来实现高电压，并消除任何可能性分流电流和电解质泄漏，从而提高可靠性和安全性。原型电容器单元将被制造、表征和测试。这些装置将与标准电容器进行比较，以评估项目的整体效益。将与行业领导者合作制定和确定包装策略。将制造并操作单元电容器以证明概念可行性。第二阶段将扩大研究范围，以优化和标准化流程和设计，a) 制造最终的电池堆，评估电容器外壳、封装材料和程序，b) 进行长期稳定性和生物相容性测试，以及 c) 研究和选择灭菌和包装选项。公共卫生相关性植入式心脏复律除颤器 (ICD) 的使用已成为一种越来越被接受的治疗选择，每年可以挽救数千名心脏病患者的生命。 ICD 迫切需要尺寸减小、能量密度高的电容器。 ICD 内部电容器的体积和重量的大幅减少将代表 ICD 产品的重大改进，从而为患者带来许多好处。