Flow Cytometry Core

流式细胞术核心

• 批准号: 10630389
• 负责人: MARK S DOONER
• 金额: $ 21.32万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10630389
• 关键词: Advisory Services; Aging; Area; Basic Science; Biomedical Research; Buffers; Cell Separation; Cells; Centers of Research Excellence; Clinical; Clinical Research; Collaborations; Communities; Core Facility; Cytometry; Data Collection; Data Storage and Retrieval; Dedications; Discipline; Experimental Designs; Flow Cytometry; Goals; Growth; Health Personnel; Hospitals; Human Resources; Inductively Coupled Plasma Mass Spectrometry; Institution; Lasers; Longevity; Mass Spectrum Analysis; Phase; Phenotype; Pilot Projects; Population; Positioning Attribute; Property; Research; Research Activity; Research Personnel; Research Project Grants; Resources; Rhode Island; Role; Services; Sodium Chloride; Solid; Source; Suspensions; System; Techniques; Technology; Tissues; Universities; instrumentation; laser cell sorter; particle; programs; single cell analysis; stem cells; success; time of flight mass spectrometry; tool

Flow Cytometry Core Abstract The Flow Cytometry Core was initially formed to fulfill the flow cytometry needs of the projects and pilot projects of the original COBRE Phase I application. The Core provided expertise in stem cell and rare cell separations, cell sorting and cell phenotyping analysis, by making available, state-of-the-art instrumentation for the flow cytometry needs of the COBRE investigators as well as the clinical and basic research community in Rhode Island. Today, the Flow Cytometry Core continues to fulfill this critical role and supports a multitude of research programs, projects and diverse research areas at Rhode Island Hospital and different institutions in the state of Rhode Island. It remains heavily utilized, partially due to the strong support and success of the COBRE’s here in Rhode Island but also the strategic importance and basic relevance that flow cytometry brings to the research community at large. This is the only research flow cytometry core facility at Rhode Island Hospital and the only research flow cytometry core facility that offers access to a 5-laser sorter, 4-laser analyzer and a mass cytometer in the state. Flow cytometry remains an extremely useful tool for researchers over many different research disciplines. The institution has been generous with its administrative and fiscal support of the Flow Cytometry Core. Notably, this year Rhode Island Hospital has purchased and installed, a Fluidigm Helios CyTOF system, that is now available through the COBRE Flow Cytometry Core. This CyTOF platform will be utilized by clinical and basic researchers in the State of Rhode Island and shows a high level of support and dedication to the success of the proposed COBRE Flow Cytometry Core. With the new state-of-the-art instrumentation and Core expansion plan directed towards expanding inclusion of clinical research projects, our Core is well positioned to continue its growth and achieve long-term financial sustainability.

流式细胞仪核心 抽象的 流式细胞仪核心最初是为满足项目和试点项目的流式细胞仪需求而形成的 原始的cobre i阶段应用程序。核心提供了干细胞和稀有细胞分离的专业知识， 通过提供流量的最先进的仪器，细胞分选和细胞表型分析 毛绒研究人员以及Rhode的临床和基础研究社区的细胞仪需求 岛。如今，流式细胞仪核心继续履行这一关键作用，并支持大量研究 罗德岛医院和不同机构的计划，项目和各种研究领域 罗德岛。它仍然被大量利用，部分是由于Cobre的强烈支持和成功 在罗德岛州，以及流式细胞术带来的战略重要性和基本相关性 整个社区。这是罗德岛医院唯一的研究流式细胞仪核心设施，也是唯一的 研究流式细胞仪核心设施，可访问5射线器分选仪，4射线器分析仪和质量细胞图仪 在州。对于许多不同研究，流式细胞仪仍然是研究人员的极其有用的工具 学科。该机构对流式细胞仪的行政和财政支持非常慷慨 核。值得一提 现在可以通过毛流式细胞仪核心获得。这个细胞平台将通过临床利用 以及罗德岛州的基础研究人员，并显示了高水平的支持和奉献精神 所提出的cobre流式细胞仪核心的成功。使用新的最先进的仪器和核心 扩展计划致力于扩展临床研究项目，我们的核心良好 继续增长并实现长期的财务可持续性。