Prevalence of syphilis and other sexually transmitted infections in men and transgender women who have sex with men in Cali, Colombia

哥伦比亚卡利男男性行为者和跨性别女性梅毒和其他性传播感染的患病率

• 批准号: 10559087
• 负责人: Michael Anthony Moody
• 金额: $ 9.76万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10559087
• 关键词: AIDS/HIV problem; Administrative Supplement; Adolescent and Young Adult; Affect; Anal Sex; Attitude to Health; Award; Birth; Blood Banks; Caring; Chlamydia; Cities; Clinical; Collaborations; Colombia; Communities; Connecticut; Data; Diagnosis; Drug user; Economics; Enrollment; Fellowship; Female; Funding; Gonorrhea; HIV; HIV Infections; Health; Health Knowledge Attitudes Practice; Health Personnel; Healthcare; Hepatitis B; Hepatitis C; Hospitals; Human Papillomavirus; Incentives; Incidence; Income; Infrastructure; International; Intervention; Laboratories; Link; Mandatory Reporting; Measures; Membrane Proteins; Methods; National Institute of Allergy and Infectious Disease; Parents; Participant; Patient Recruitments; Patients; Persons; Policies; Policy Maker; Population; Positioning Attribute; Prevalence; Prevalence Study; Prevention; Prevention strategy; Preventive; Prostitution; Public Health; Reporting; Research; Research Proposals; Respondent; Risk Assessment; Risk Factors; Sampling; Serology; Services; Sexual Health; Sexual Partners; Sexual Transmission; Sexual and Gender Minorities; Sexually Transmitted Diseases; Site; Stigmatization; Study models; Syphilis; Syphilis Serodiagnosis; System; Testing; Therapeutic; Treponema pallidum; Trust; United States National Institutes of Health; Universities; Ursidae Family; Validation; Viral hepatitis; Weight; Woman; epidemiological model; epidemiology study; experience; gender minority group; high risk; male; medical schools; men; men who have sex with men; national surveillance; neglect; peer; population health; programs; rapid test; recruit; sample collection; screening; serosurvey; sex; sexual minority; sexually active; social exclusion; syphilis vaccine; transgender; transgender men; transgender women; transgender women who have sex with men

PROJECT SUMMARY Sexually transmitted infections (STIs) continue to be a major public health problem afflicting millions of people worldwide. Sexual and gender minorities (SGM), including men who have sex with men (MSM) and transgender women, bear a high burden of STIs, while reporting higher rates of risk factors, economic marginalization, social exclusion, and stigmatization which hinders their access to preventive and therapeutic options for STIs. Little information is available in Colombia regarding the prevalence of STIs in SGMs or the risk factors linked to acquiring and transmitting STIs. The current proposal incorporates the use of Respondent Driven Sampling to recruit a group of transgender women and MSM for STI testing and risk assessment in these often hard to reach populations. This project will use RDS to obtain data to assess the unmet need for prevention, diagnosis, and treatment of STIs in MSM and other SGM populations. It will also facilitate enrollment of transgender women into our U-19 syphilis project. The central overarching hypothesis of our study is that in MSM and transgender women who have sex with other men in Cali, Colombia there is a high, unrecognized prevalence of syphilis, gonorrhea, chlamydia, HPV, and viral hepatitis. To test our hypothesis, we propose to use Respondent Driven Sampling to estimate the prevalence of STIs in MSM and transgender women who have sex with men, in Cali, Colombia. In addition, we will quantify metrics of sexual health, knowledge, attitudes and practices of these populations. It is our contention that this approach will undercover the hidden burden and unmet sexual health needs of these populations and will allow policy makers, health care providers and the local community to act upon this information through intervention planning.

项目概要 性传播感染（STI）仍然是困扰数百万人的主要公共卫生问题 世界各地的人们。性少数群体 (SGM)，包括男男性行为者 (MSM) 和 跨性别女性承受着沉重的性传播感染负担，同时报告的风险因素、经济 边缘化、社会排斥和污名化阻碍了他们获得预防和治疗服务 性传播感染的治疗选择。哥伦比亚关于性传播感染流行情况的信息很少 SGM 或与感染和传播性传播感染相关的风险因素。目前的提案包括 使用受访者驱动抽样招募一组跨性别女性和 MSM 进行 STI 检测 对这些往往难以接触到的人群进行风险评估。本项目将使用RDS获取数据 评估 MSM 和其他 SGM 中性传播感染预防、诊断和治疗方面未满足的需求 人口。它还将促进跨性别女性加入我们的 U-19 梅毒项目。这 我们研究的核心总体假设是，在 MSM 和跨性别女性中，与 在哥伦比亚卡利的其他男性中，梅毒、淋病、衣原体、 HPV和病毒性肝炎。为了检验我们的假设，我们建议使用受访者驱动抽样来 估计哥伦比亚卡利的男男性行为者和与男性发生性关系的跨性别女性中性传播感染的患病率。 此外，我们还将量化性健康、知识、态度和实践的指标 人口。我们认为，这种方法将掩盖隐藏的负担和未满足的性行为 这些人群的健康需求，并将允许政策制定者、卫生保健提供者和当地 社区通过干预计划根据这些信息采取行动。