Core 1: Biostatistics

核心1：生物统计学

• 批准号: 10220872
• 负责人: DONNA S. NEUBERG
• 金额: $ 2.06万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-19 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10220872
• 关键词: Animals; Basic Science; Biometry; Biostatistics Core; Clinical; Collaborations; Consultations; Development; Goals; Intervention; Investigation; Molecular; Myeloid Leukemia; Myeloproliferative disease; Participant; Program Development; Research; Research Personnel; Research Project Grants; Resources; Services; Statistical Methods; Techniques; Training; career; career development; design; experimental study; member; pre-clinical; programs; Animals; Basic Science; Biometry; Biostatistics Core; Clinical; Collaborations; Consultations; Development; Goals; Intervention; Investigation; Molecular; Myeloid Leukemia; Myeloproliferative disease; Participant; Program Development; Research; Research Personnel; Research Project Grants; Resources; Services; Statistical Methods; Techniques; Training; career; career development; design; experimental study; member; pre-clinical; programs

Project Summary/Abstract The purpose of Core1 Biostatistics is to provide statistical support to all the Projects, Programs, and Cores in this SPORE in Myeloid Malignancies. For the Projects, Developmental Research Projects, and the Cores, this assures that the design, conduct, and analyses of all experiments—clinical, correlative, animal, or basic science--use robust statistical techniques that are appropriately implemented. For the Career Enhancement Program, this Core provides biostatistical support and training for junior investigators. Through these aims, this central resource helps to elucidate the diverse molecular mechanisms that underlie myeloid malignancies, and assess the vulnerability of those mechanisms to clinical intervention.

项目摘要/摘要 Core1生物统计学的目的是为所有项目，计划和核心提供统计支持 这是髓样恶性肿瘤中的孢子。对于项目，发展研究项目和核心， 假设所有实验的设计，进行和分析 - 临床，相关，动物或基本 科学 - 使用适当实施的强大统计技术。为了提高职业 程序，该核心为初级研究人员提供了生物统计学支持和培训。通过这些目标， 这种中央资源有助于阐明髓样恶mal的潜水员分子机制，即 并评估这些机制对临床干预的脆弱性。