Bioinformatics and Biostatistics Core

生物信息学和生物统计学核心

• 批准号: 10709233
• 负责人: Ying Yuan
• 金额: $ 22.6万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-19 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10709233
• 关键词: Animals; Basic Science; Bioinformatics; Biometry; Biostatistics Core; Clinical Sciences; Clinical Trials; Data; Data Analyses; Data Analytics; Data Set; Databases; Development; Ensure; Genomics; Goals; Lateral; Logistics; Malignant neoplasm of ovary; Methodology; Methods; Paper; Publications; Publishing; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Resources; Statistical Data Interpretation; Translational Research; University of Texas M D Anderson Cancer Center; Work; archive data; career; computerized data processing; data acquisition; data handling; data management; design; experience; experimental study; high throughput screening; innovation; member; programs; statistics; success; Animals; Basic Science; Bioinformatics; Biometry; Biostatistics Core; Clinical Sciences; Clinical Trials; Data; Data Analyses; Data Analytics; Data Set; Databases; Development; Ensure; Genomics; Goals; Lateral; Logistics; Malignant neoplasm of ovary; Methodology; Methods; Paper; Publications; Publishing; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Resources; Statistical Data Interpretation; Translational Research; University of Texas M D Anderson Cancer Center; Work; archive data; career; computerized data processing; data acquisition; data handling; data management; design; experience; experimental study; high throughput screening; innovation; member; programs; statistics; success

Core B: Bioinformatics and Biostatistics Core SUMMARY/ABSTRACT The primary goal of the Bioinformatics and Biostatistics Core is to provide centralized biostatistics, bioinformatics, and database support for all SPORE projects and cores, ranging from basic science studies to animal studies to genomics studies to clinical trials. The Core will serve multiple needs for the planning and conduct of the SPORE's translational research. Based on a strong track record of providing biostatistical support for translational research, the Core will be a comprehensive, multilateral resource for designing clinical and basic science experiments, performing statistical analyses, developing innovative statistical methodology, and publishing the research results generated from the SPORE. The Core will confer regularly with project investigators to discuss the design and conduct of research projects, evaluate results of analyses, discuss potential new research initiatives and directions within the SPORE, and promote the publication of findings. To serve all proposed SPORE Projects, as well as the Career Enhancement and Developmental Research Programs, the Bioinformatics and Biostatistics Core has the following specific aims: Specific Aim 1: Provide statistics and data analyses required for the Projects and Cores to achieve their specific aims; Specific Aim 2: Provide bioinformatics expertise required for analyses and interpretation of high-throughput assay data; Specific Aim 3: Assist with design and implementation of new trials and studies arising from SPORE research; Specific Aim 4: As necessary, to develop and adapt innovative statistical and bioinformatics methods pertinent to ovarian cancer studies.

核心B：生物信息学和生物统计学核心摘要/摘要 生物信息学和生物统计学核心的主要目标是提供集中的生物统计学， 从基础科学研究到所有孢子项目和核心的生物信息学和数据库支持 动物研究对临床试验的基因组学研究。核心将满足计划的多种需求， 孢子翻译研究的进行。基于提供生物统计支持的强大记录 对于翻译研究，核心将是设计临床和的全面多边资源 基础科学实验，进行统计分析，开发创新的统计方法和 发布孢子产生的研究结果。核心将定期与项目交流 研究人员讨论研究项目的设计和行为，评估分析结果，讨论 潜在的新研究计划和孢子中的指示，并促进发现的发布。 为所有拟议的孢子项目以及职业增强和发展研究服务 计划，生物信息学和生物统计学核心具有以下特定目的： 具体目标1：提供项目和核心所需的统计和数据分析以实现其特定 目标； 特定目的2：提供分析和解释高通量所需的生物信息学专业知识 测定数据； 特定目的3：协助设计和实施孢子研究引起的新试验和研究； 特定目的4：必要时要开发和适应创新的统计和生物信息学方法 进行卵巢癌研究。