Bioinformatics and Biostatistics Core

生物信息学和生物统计学核心

• 批准号: 10709233
• 负责人: Ying Yuan
• 金额: $ 22.6万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-19 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10709233
• 关键词: Animals; Basic Science; Bioinformatics; Biometry; Biostatistics Core; Clinical Sciences; Clinical Trials; Data; Data Analyses; Data Analytics; Data Set; Databases; Development; Ensure; Genomics; Goals; Lateral; Logistics; Malignant neoplasm of ovary; Methodology; Methods; Paper; Publications; Publishing; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Resources; Statistical Data Interpretation; Translational Research; University of Texas M D Anderson Cancer Center; Work; archive data; career; computerized data processing; data acquisition; data handling; data management; design; experience; experimental study; high throughput screening; innovation; member; programs; statistics; success

Core B: Bioinformatics and Biostatistics Core SUMMARY/ABSTRACT The primary goal of the Bioinformatics and Biostatistics Core is to provide centralized biostatistics, bioinformatics, and database support for all SPORE projects and cores, ranging from basic science studies to animal studies to genomics studies to clinical trials. The Core will serve multiple needs for the planning and conduct of the SPORE's translational research. Based on a strong track record of providing biostatistical support for translational research, the Core will be a comprehensive, multilateral resource for designing clinical and basic science experiments, performing statistical analyses, developing innovative statistical methodology, and publishing the research results generated from the SPORE. The Core will confer regularly with project investigators to discuss the design and conduct of research projects, evaluate results of analyses, discuss potential new research initiatives and directions within the SPORE, and promote the publication of findings. To serve all proposed SPORE Projects, as well as the Career Enhancement and Developmental Research Programs, the Bioinformatics and Biostatistics Core has the following specific aims: Specific Aim 1: Provide statistics and data analyses required for the Projects and Cores to achieve their specific aims; Specific Aim 2: Provide bioinformatics expertise required for analyses and interpretation of high-throughput assay data; Specific Aim 3: Assist with design and implementation of new trials and studies arising from SPORE research; Specific Aim 4: As necessary, to develop and adapt innovative statistical and bioinformatics methods pertinent to ovarian cancer studies.

核心 B：生物信息学和生物统计学核心摘要/摘要 生物信息学和生物统计学核心的主要目标是提供集中的生物统计学， 所有 SPORE 项目和核心的生物信息学和数据库支持，范围从基础科学研究到 动物研究、基因组学研究、临床试验。核心将满足规划和 SPORE 的转化研究的进行。基于提供生物统计支持的良好记录 对于转化研究，核心将是一个全面的多边资源，用于设计临床和 基础科学实验，进行统计分析，开发创新的统计方法，以及 发布 SPORE 产生的研究结果。核心将定期与项目进行协商 研究人员讨论研究项目的设计和实施，评估分析结果，讨论 SPORE 内潜在的新研究举措和方向，并促进研究结果的发表。 为所有拟议的 SPORE 项目以及职业提升和发展研究提供服务 生物信息学和生物统计学核心项目有以下具体目标： 具体目标 1：提供项目和核心实现其具体目标所需的统计数据和数据分析 目标； 具体目标 2：提供高通量分析和解释所需的生物信息学专业知识 化验数据； 具体目标 3：协助设计和实施 SPORE 研究产生的新试验和研究； 具体目标 4：必要时开发和采用相关的创新统计和生物信息学方法 卵巢癌研究。