Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program

约翰·霍普金斯大学艾滋病流行病学和预防科学培训计划

• 批准号: 9897479
• 负责人: Christopher C. Beyrer
• 金额: $ 40.36万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9897479
• 关键词: Epidemiology; HIV; Prevention; Science; Training Programs

7. PROJECT SUMMARY This proposal is a renewal application for a second 5-year National Research Service Award Institutional Research Grant to support a training program in HIV Epidemiology and Prevention Sciences at the Johns Hopkins Bloomberg School of Public Health (BSPH) and the Johns Hopkins School of Medicine (SOM), entitled the “Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program.” The program is led by Director Chris Beyrer MD, MPH, and Deputy Director Shruti Mehta PhD, MPH. We are requesting support for 3 pre- and 4 post-doctoral trainees, which represents an increase of 2 post-doctoral trainees from our prior funding period. The program mission is to train pre-doctoral students and post-doctoral fellows to become leaders at the forefront of highest priority HIV research with advanced competencies and state-of-the-art skills in three training tracks: HIV Epidemiology and Implementation Science Methods including training in (1) Populations and Study Designs, including identification, recruitment and retention; (2) Measurement issues in HIV populations, including innovative methods for surveillance, recruitment, estimation of HIV prevalence and incidence, (3) Inference techniques, including modern analytical methods for causal inference and mathematical modeling; and (4) Synthesis and Implementation of research findings to public health practice; HIV Clinical and Laboratory Sciences including training in (1) the epidemiology, prevention and treatment of major co- infections with HIV including hepatitis C virus (HCV) infection and tuberculosis; (2) epidemiology and pathogenesis of HIV and age-associated co-morbidities; and (3) Measurement and use of genetic, virologic and immunologic factors that can inform our knowledge of the pathogenesis and transmission of HIV; HIV Prevention Sciences including how to prevent and reduce the prevalence and incidence of HIV through training in (1) Design and Analysis of HIV biomedical, behavioral and combination prevention trials, including treatment as prevention research (TasP), oral and topical PrEP trials, HIV vaccine trials and passive immune-therapy trials, and (2) Community-based population-level approaches to HIV prevention and control beyond individual behavior change. Our program, which is fully integrated through the JHU Center for AIDS Research (CFAR) has resulted in a rich and interactive environment for trainees working in HIV augmented by the exceptionally innovative, productive and collaborative HIV research conducted by epidemiological, clinical, prevention and implementation scientists throughout Johns Hopkins BSPH, and SOM.

7. 项目概要 本提案是第二个五年期国家研究服务奖机构的续展申请 研究补助金支持约翰斯学院艾滋病毒流行病学和预防科学培训项目 霍普金斯大学彭博公共卫生学院 (BSPH) 和约翰霍普金斯大学医学院 (SOM)， 题为“约翰·霍普金斯大学艾滋病毒流行病学和预防科学培训计划”。 该计划由主任 Chris Beyrer（医学博士、公共卫生硕士）和副主任 Shruti Mehta 博士、公共卫生硕士领导。 请求支持3名博士前培训生和4名博士后培训生，这意味着增加了2名博士后培训生 该项目的任务是培养博士前学生和博士后。 研究员成为最优先的艾滋病毒研究最前沿的领导者，具有先进的能力和 三个培训方向的最先进技能：艾滋病毒流行病学和实施科学方法 包括 (1) 人群和研究设计方面的培训，包括识别、招募和保留 (2) HIV 人群的测量问题，包括监测、招募、估计的创新方法 HIV 患病率和发病率的分析，(3) 推理技术，包括因果关系的现代分析方法 推理和数学建模；以及（4）向公众综合和实施研究成果 健康实践；艾滋病毒临床和实验室科学，包括 (1) 流行病学、预防方面的培训 以及治疗主要的艾滋病毒合并感染，包括丙型肝炎病毒（HCV）感染和结核病（2）； HIV 的流行病学和发病机制以及与年龄相关的合并症；以及 (3) 测量和使用 遗传、病毒学和免疫学因素可以帮助我们了解发病机制和传播 艾滋病毒预防科学，包括如何预防和减少艾滋病毒的流行和发病率 通过以下方面的培训：(1) HIV 生物医学、行为和组合预防试验的设计和分析， 包括治疗即预防研究 (TasP)、口服和局部 PrEP 试验、HIV 疫苗试验和被动治疗 免疫治疗试验，以及 (2) 以社区为基础的人群层面的艾滋病毒预防和控制方法 我们的计划与 JHU 艾滋病中心完全整合。 研究 (CFAR) 为从事艾滋病毒工作的学员创造了一个丰富的互动环境， 由流行病学、临床、 约翰霍普金斯大学 BSPH 和 SOM 的预防和实施科学家。