Hermanos de Luna y Sol: A community-based HIV prevention intervention

Hermanos de Luna y Sol：基于社区的艾滋病毒预防干预措施

基本信息

批准号：
10626689
负责人：
Jesus Ramirez-Valles
金额：
$ 71.84万
依托单位：
SAN FRANCISCO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-07-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10626689
关键词：
AIDS prevention Acquired Immunodeficiency Syndrome Address Affect Area Awareness Behavioral Biomedical Research Bisexual Buffers Centers for Disease Control and Prevention (U.S.)Chicago Cities Collaborations Communities Community Health Country Diagnosis Discrimination Effectiveness of Interventions Equation Ethnic Origin Evidence based intervention Face Fostering Gays Goals Government HIV HIV Infections HIV diagnosis HIV disparities HIV risk Health Heart Hispanic-serving Institution Homophobia Human Resources Human immunodeficiency virus test Immigrant Incidence Individual Inequity Informal Social Control Interdisciplinary Study Intervention Intervention Studies Language Latin American Latino Latino Population Latinx Latinx population Lead Location Minority-Serving Institution Modeling National Institute of Mental Health National Institute on Minority Health and Health Disparities Observational Study Participant Patient Recruitments Persons Population Prevalence Quasi-experiment Race Racial Equity Randomized Research Risk Risk Behaviors Sampling Sampling Biases Self Perception Sexual Health Shapes Social isolation Social support Testing Time Translations United States United States National Institutes of Health Unsafe Sex Use Effectiveness Woman base bilingualism community building community involvement community organizations contextual factors design distrust effective intervention effectiveness evaluation ethnic minority population experience group intervention health disparity health equity health inequalities improved infection rate innovation insight male marginalized community marginalized population member men men who have sex with men migration multidisciplinary novel pedagogy pre-exposure prophylaxis prevent preventive intervention prospective psychological distress public health priorities public health relevance queer racism recruit self esteem sexual minority group sexual risk behavior social social culture social epidemiology sociocultural determinant therapy design time use uptake volunteer

项目摘要

Abstract The overall goal of our research is to reduce HIV-related health inequities among Latinx immigrant populations. We propose to determine the effectiveness of Hermanos de Luna y Sol (HLS), a community-based, group intervention delivered in Spanish, designed to reduce HIV sexual risk among Latinx immigrants who identify as gay/bisexual men or men who have sex with men (GBMSM). The study is designed as a quasi-experimental, community control, with Oakland, CA as the intervention group and Chicago, IL as the control. Assessments will be conducted at -3 and 0 mos., and follow-ups at 3, 6, and 12 mos. Participants (N=360; n=180 per city) will be recruited using Time-location sampling (a venue-based sampling designed to reduce sample bias). HLS, the intervention at the heart of this study, offers several novel features: it focuses on immigrant, Spanish- speaking populations; it addresses racism and homophobia as factors shaping HIV risk; and uses a community-based approach centered on community involvement (e.g., civic participation, volunteering) as a means to foster sexual health and community building. The study will help identify effective interventions to prevent HIV among Latinx immigrant GBMSM, a marginalized population for which HIV preventive interventions are severely lacking. This study capitalizes on an existing intervention designed for Spanish speaking populations; is the first of its kind to rigorously test the intervention’s effectiveness among Latinx immigrant GBMSM using a community control design. The study applies the best possible scientific approach to obtain estimates of intervention effectiveness. If successful, the intervention would be relatively easy to disseminate via community organizations and the Centers for Disease Control and Prevention. Ultimately, the study will help move forward efforts to reduce racial/ethnic health inequities, one of the nation’s major public health priorities. This proposal is directly relevant to the RFA on Transformative Research to Address Health Disparities and Advance Health Equity at Minority serving Institutions. The project is led by SFSU – a Hispanic Serving Institution-- in collaboration with two Latinx community-based organizations: La Familia and Chicago Queer Latinx Collaborative. We are a multidisciplinary research team with the depth and breadth of experience on HIV prevention with Latinx and GBMSM communities to successfully conduct the study. All senior personnel are of Latin American descent, fully bilingual (Spanish and English), and three of them are women. The proposed study is strongly aligned with NIH UNITED Initiative of fostering racial equity and inclusion in biomedical research and is responsive to priority areas of multiple NIH institutes and centers, such NIMHD, NIMH, and the Office of AIDS Research.

抽象的我们研究的总体目的是减少拉丁裔移民人群中与HIV相关的健康不平等。我们建议确定Hermanos de Luna y Sol（HLS）的有效性，这是一个社区的团体以西班牙语进行的干预措施，旨在减少识别为拉丁裔移民的艾滋病毒性风险与男人发生性关系的同性恋/双性恋男人（GBMSM）。该研究被设计为准实验性，社区控制，加利福尼亚州奥克兰作为干预小组和伊利诺伊州芝加哥作为控制。评估将在-3和0 mos。进行，然后在3、6和12 MOS进行随访。参与者（n = 360; n =每个城市180）将使用时间点采样（一种基于场地的采样旨在减少样本偏差）招募。 HLS是这项研究核心的干预措施，提供了几种新颖的特征：它的重点是移民，西班牙语 - 说话人群；它将种族主义和同性恋恐惧症作为塑造艾滋病毒风险的因素；并使用基于社区的方法以社区参与为中心（例如，公民参与，志愿服务）意味着促进性健康和社区建设。该研究将有助于确定有效的干预措施，以防止拉丁裔移民GBMSM之间的艾滋病毒严重缺乏艾滋病毒预防干预措施的边缘化人群。这项研究大写了为西班牙语人群设计的现有干预措施；是第一个严格测试干预使用社区控制设计在Latinx移民GBMSM中的有效性。研究采用最佳科学方法来获得干预效果的估计。如果成功，干预相对容易通过社区组织和疾病中心传播控制与预防。最终，这项研究将有助于努力减少种族/种族健康不平等是美国主要的公共卫生重点之一。该提案与RFA有关变革性研究的RFA直接相关，以解决健康差异和在少数民族服务机构中提高卫生公平。该项目由SFSU领导 - 西班牙裔服务机构 - 与两个基于拉丁裔社区的组织合作：La Familia和芝加哥酷儿 Latinx合作。我们是一个多学科研究团队，具有深度和广度的经验与Latinx和GBMSM社区预防HIV，以成功进行这项研究。所有高级人员是拉丁美洲血统，完全双语（西班牙语和英语），其中三个是女性。拟议的研究与NIH United促进种族公平和包容性的计划密切一致生物医学研究，对多个NIH机构和中心的优先领域，此类NIMHD， NIMH和艾滋病研究办公室。