Genomics and Molecular Biology

基因组学和分子生物学

• 批准号: 8804005
• 负责人: CRAIG R TOMLINSON
• 金额: $ 17.1万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-04 至 2019-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8804005
• 关键词: Address; Budgets; Cancer Center Support Grant; Cell Separation; Communication; Communities; Consultations; DNA; DNA Sequence Alteration; Data; Data Analyses; Dideoxy Chain Termination DNA Sequencing; Doctor of Philosophy; Educational workshop; Equipment and supply inventories; Experimental Designs; Future; Generations; Genome; Genomics; Genomics Shared Resource; Genotype; Immunology; Ions; Laboratories; Learning; Lebanon; Libraries; Malignant Neoplasms; Methods; Methylation; Molecular; Molecular Biology; Molecular Biology Shared Resource; Mutation; Norris Cotton Cancer Center; Nucleic Acids; Plasma Cells; Procedures; RNA; Radiobiology; Research; Research Personnel; Resource Sharing; Services; Specialist; Technology; Therapeutic; Transcript; abstracting; base; cancer epidemiology; cancer imaging; cancer immunotherapy; data management; exome; experience; genome sequencing; good laboratory practice; improved; instrumentation; meetings; nano-string; next generation sequencing; programs; symposium; targeted sequencing; technology/technique; tool; tumor

Project Summary/Abstract: Genomics & Molecular Biology Shared Resource The Genomics & Molecular Biology Shared Resource (GMBSR) was created in 2013 by combining the Genomics Shared Resource with the Molecular Biology Shared Resource. The merger enhanced the communication between the cores, maximized the utilization of staff expertise, and raised the quality of services offered to researchers. The GMBSR offers next generation sequencing (Ion Torrent and Illumina) and Sanger sequencing in addition to microarray services (Illumina and Affymetrix), NanoString technology, and shared instrumentation, including qPCR thermocyclers. Mandatory free consultation regarding experimental design and budget estimates are provided to every researcher initiating a new project. The GMBSR is directed by Craig Tomlinson, PhD, with Genomics located in Lebanon at the Norris Cotton Cancer Center (NCCC), while Molecular Biology is based on the Hanover campus. Genomics, overseen by Co-Director Joanna Hamilton, PhD, includes an experienced technician and a bioinformaticist. Molecular Biology is led by Co- Director Dr. Yolanda Sanchez, PhD, and is staffed by a Senior Technician/Manager and a technical specialist. The GMBSR is the most widely used NCCC Shared Resource, supporting over 170 biomedical laboratories in the Dartmouth research community, of which approximately one-half are laboratories led by NCCC investigators in five of the six NCCC Research Programs (Cancer Epidemiology, Cancer Mechanisms, Molecular Therapeutics, Cancer Imaging & Radiobiology, and Immunology & Cancer Immunotherapy). The rapidly changing field of Genomics presents unique challenges to the GMBSR. To meet the needs of and to inform NCCC investigators, the GMBSR conduct workshops, present at laboratory meetings and tumor boards; speak at local seminars, and attend national and regional technology conferences to learn the latest technologies, techniques, and methods.

项目摘要/摘要：基因组学和分子生物学共享资源 基因组学和分子生物学共享资源（GMBSR）是在2013年创建的 基因组学与分子生物学共享资源共享资源。合并增强了 核心之间的沟通，最大化员工专业知识的利用，并提高了 提供给研究人员的服务。 GMBSR提供下一代测序（离子Torrent和Illumina）和 Sanger测序除了微阵列服务（Illumina和Affymetrix），纳米串技术和 共享仪器，包括QPCR热环激体。关于实验的强制免费咨询 设计和预算估算均可为每个启动一个新项目的研究人员提供。 GMBSR是指导的 由Craig Tomlinson博士学位，基因组学位于黎巴嫩，位于诺里斯棉花癌中心（NCCC）， 而分子生物学基于汉诺威校园。基因组学，由联合导演乔安娜监督 汉密尔顿（Hamilton）博士包括一位经验丰富的技术员和一位生物信息学家。分子生物学由共同领导 主任Yolanda Sanchez博士博士，由高级技术员/经理和技术专家组成。 GMBSR是最广泛使用的NCCC共享资源，支持170多种生物医学实验室 达特茅斯研究界，大约一半是由NCCC领导的实验室 六个NCCC研究计划中的五个研究人员（癌症流行病学，癌症机制， 分子疗法，癌症成像和放射生物学以及免疫学和癌症免疫疗法）。这 基因组学的快速变化领域给GMBSR带来了独特的挑战。满足和满足的需求 通知NCCC调查人员，GMBSR进行讲习班，在实验室会议和肿瘤委员会举行； 在当地研讨会上发表讲话，参加国家和地区技术会议以学习最新 技术，技术和方法。