Purchase Ventilated Caging Systems to Expand Mouse Housing Capacity

购买通风笼系统以扩大小鼠饲养容量

基本信息

批准号：
8710718
负责人：
Debra L Hickman
金额：
$ 50万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-07-01 至 2015-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8710718
关键词：
Air Allergens Ammonia Animal Experimentation Animal Housing Animal Welfare Animals Applications Grants Carbon Dioxide Coupling Diabetes Mellitus Employee Environment Excision Exposure to Faculty Funding Genetically Engineered Mouse Health House mice Housing Human Resources Indiana Industry Infectious Agent Injury Laboratory Animals Malignant Neoplasms Manufactured Supplies Movement Mus Peer Review Personal Satisfaction Principal Investigator Recruitment Activity Research Research Infrastructure Research Personnel Resources Review Literature Rodent Savings Schools System Technology Universities Water Work animal care animal facility animal resource base density design ergonomics exhaust experience high efficiency particulate air filter improved medical schools meetings member mouse model pathogen prevent programs rapid growth square foot transmission process

项目摘要

DESCRIPTION (provided by applicant): The Indiana University School of Medicine (IUSM) has experienced a substantial increase in the use of genetically engineered mice (GEM) in recent years. These animals are critical for the School's major research focuses, including studies of cancer, diabetes, and other health problems of importance in the USA. Our rapid growth in the use of GEM has created a need for more efficient and greater housing capacity in the Laboratory Animal Resource Center (LARC). In 2009, we utilized institutional resources to build Walther Hall, a research building containing an 18,000 square foot rodent housing facility. This facility was designed to house a maximum of 12,900 cages of mice. We were able to purchase individually ventilated caging systems representing approximately 10,000 cages of mice when the building opened. Funds from this grant proposal will be used to purchase 14 Modular Animal Caging Systems (MACS(R), Alternative Design Manufacturing & Supply, Inc.) with associated automatic watering system (Edstrom Industries, Inc) capabilities for our Walther Hall animal facility to add 2,240 cages, increasing the housing capacity of this animal facility. This represents a 22% increase in the housing capacity for the Walther Hall animal facility. The purchase of these additional individually ventilated caging systems will allow us to meet our specific aims of increasing the available housing capacity required by our principal investigators, protecting the health and well-being of the mice, providing personnel protection for the employees working in the animal facilities, and increasing the operational efficiencies of the animal facility.

描述（由申请人提供）：近年来，印第安纳大学医学院（IUSM）对基因工程小鼠（GEM）的使用大幅增加。这些动物对于学院的主要研究重点至关重要，包括癌症、糖尿病和美国其他重要健康问题的研究。我们对 GEM 使用的快速增长需要实验动物资源中心 (LARC) 更高效、更大的容纳能力。 2009 年，我们利用机构资源建造了 Walther Hall，这是一座研究大楼，内有 18,000 平方英尺的啮齿动物住房设施。该设施最多可容纳 12,900 个老鼠笼。大楼开业时，我们购买了独立通风的笼舍系统，可容纳大约 10,000 个老鼠笼。本拨款提案的资金将用于购买 14 个模块化动物笼养系统（MACS(R)，替代设计制造和供应公司）以及相关的自动浇水系统（Edstrom Industries, Inc）功能，为我们的 Walther Hall 动物设施添加2,240 个笼子，增加了该动物设施的容纳能力。这意味着 Walther Hall 动物设施的容纳能力增加了 22%。购买这些额外的独立通风笼式系统将使我们能够实现增加主要研究人员所需的可用住房容量的具体目标，保护小鼠的健康和福祉，为动物设施中工作的员工提供人员保护，并提高动物设施的运营效率。