Techniplast Sealsafe Plus Mouse Rack System (LAMb)

Techniplast Sealsafe Plus 鼠标架系统 (LAMb)

• 批准号: 8951325
• 负责人: Philip S Tsao
• 金额: --
• 依托单位: VETERANS ADMIN PALO ALTO HEALTH CARE SYS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-01-01 至 2015-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8951325
• 关键词: Air; Allergens; Ammonia; Animal Experimentation; Animal Housing; Animal Husbandry; Animal Welfare; Animals; Area; Award; Carbon Dioxide; Characteristics; Consumption; Containment; Docking; Duct (organ) structure; Dust; Ensure; Environment; Equipment; Floor; Growth; Health; Heating; House mice; Housing; Individual; Label; Length; Manufacturer Name; Mental Depression; Microprocessor; Modeling; Mus; Noise; Oxygen; Performance; Plastics; Population; Price; Research Personnel; Research Project Grants; Rodent; Safety; Side; Silicones; Stainless Steel; Stress; System; Visual; Water; Water consumption; Weight; animal colony; anxious behavior; cost; flexibility; pathogen; polysulphone; prevent; programs; public health relevance; touchscreen

 DESCRIPTION (provided by applicant): In order to maintain the health of the animal colony, principles of animal husbandry that provide an ideal environment for the animals is essential. Consistent with federal mandated practices, the requested equipment will maximize the comfort and health of the animals, minimize moisture and ammonia levels in the cages, and provide an effective barrier from possible pathogens. The requested individual ventilated caging provides an ideal microenvironment for the animal. If this request is awarded, we can house all our mice in ventilated racks, except for mice housed in our BSL-2 suite that cannot accommodate a ventilated rack. Not only will these racks enhance the husbandry of the animals, it will also allow us to expand our housing capacity by 13%, which is essential to keep up with the growth of our animal program (currently we house approximately 18,000 mice. Expanding the number of ventilated racks will enhance our abilities to ensure the welfare of the animals, as well as, provide increased flexibility to respond to the changing needs of the investigators. As the ventilated cages house more animals than standard racks, which accommodates the growing animal usage needs of our expanding animal research program. Housing rodents in ventilated racks like Sealsafe Plus will protect them from infective agents and protect the animal users from allergens and requires a high volume of air to be blown into the cages so as to provide the optimal micro-environment, thus aiming to maintain a low concentration of ammonia, carbon dioxide and a stable concentration of oxygen.

 描述（由申请人提供）： 为了维持动物群体的健康，为动物提供理想环境的畜牧业原则至关重要，所要求的设备将最大限度地提高动物的舒适度和健康，并最大限度地减少水分和氨水平。并提供有效的屏障，防止可能的病原体。所要求的单独通风笼为动物提供了理想的微环境。如果这一要求得到满足，我们可以将所有小鼠安置在通风的架子上，除了我们饲养的小鼠。 BSL-2 套件无法容纳通风架，这些架子不仅可以改善动物的饲养，还可以让我们扩大饲养能力。 13%，这对于跟上我们动物计划的发展至关重要（目前我们饲养着大约 18,000 只小鼠。扩大通风架的数量将增强我们确保动物福利的能力，并为我们提供更大的灵活性满足研究人员不断变化的需求，因为通风笼子比标准架子容纳更多的动物，这满足了我们不断扩大的动物研究计划中不断增长的动物使用需求，例如 Sealsafe Plus。将保护它们免受传染源的侵害并保护动物使用者免受过敏原的侵害，并且需要向笼内吹入大量空气以提供最佳的微环境，从而旨在保持低浓度的氨、二氧化碳和稳定的氧气浓度。