Midlife Health in Japan (MIDJA) and the U.S. (MIDUS)

日本 (MIDJA) 和美国 (MIDUS) 的中年健康

• 批准号: 8466022
• 负责人: CAROL D. RYFF
• 金额: $ 0.5万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2017-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8466022
• 关键词: Accounting; Adult; Affect; Age; Aging; Alleles; American; Anxiety; Area; Attenuated; Biological; Biological Factors; Biological Markers; Biology; Buffers; Characteristics; Chronic; Clinic; DNA; Data; Data Collection; Data Set; Diagnosis; Disadvantaged; Economic Recession; Economics; Educational Status; Family; Gender; Genes; Genetic Markers; Genetic Polymorphism; Goals; Health; Health behavior; Income; Inflammation; Inflammatory; Interleukin-6; Japan; Japanese Population; Life; Life Cycle Stages; Link; Literature; Longitudinal Surveys; Mails; Major Depressive Disorder; Marital Status; Measures; Mediating; Mental Depression; Mental Health; Methaqualone; Modeling; Molecular Genetics; Mood Disorders; Neurosecretory Systems; Opioid; Outcome; Oxytocin Receptor; Participant; Pathway interactions; Patient Self-Report; Personal Satisfaction; Personality Traits; Population; Prevalence; Probability Samples; Process; Psychosocial Factor; Questionnaires; Receptor Gene; Regulation; Reporting; Resources; Respondent; Risk; Saliva; Sampling; Serotonin; Single Nucleotide Polymorphism; Social Responsibility; Social support; Socialization; Socioeconomic Status; Surveys; Symptoms; System; Testing; Time; Tokyo; age difference; age effect; aged; allostatic load; base; cardiovascular risk factor; comparative; cultural values; design; follow-up; immune function; low socioeconomic status; metropolitan; middle age; novel; physical conditioning; psychologic; psychosocial; resilience; satisfaction; social; social equality; socioeconomics

We propose to conduct a survey with a probability sample of Japanese adults (N = 1,000, divided equally by gender) aged 30 to 70 from the Tokyo metropolitan area. Data will be collected on sociodemographic characteristics (age, gender, marital status, educational status, income), psychosocial characteristics (e.g., independence/interdependence, personality traits, sense of control, goal orientations, social support, family obligation, social responsibility), mental health (depression, anxiety, well-being, life satisfaction), and physical health (chronic conditions, health symptoms, functional limitations, health behaviors). These measures parallel those in a national longitudinal sample of midlife Americans known as MIDUS. The central objective is to compare the Japanese sample (MIDJA) with the U.S. sample (MIDUS) to test the hypothesis that the construct of interdependence predicts well-being and health in Japan, whereas the construct of independence predicts well-being and health in the U.S. We also predict age differences in health and well-being, some suggesting cultural similarities (e.g., declining purpose in life with age) and others indicating cultural differences (e.g., more age increments on other aspects of well-being in Japan compared to the U.S.). We also propose to collect biomarkers on approximately half of the Japanese survey sample (n = 500). We will include assessments of neuroendocrine regulation, immune function, and cardiovascular risk. These will parallel biological assessments in Project 4 of the ongoing MIDUS II P01. Thus, in both cultures we will examine linkages between psychosocial factors and biology to test the hypothesis that the construct of interdependence is more strongly linked with biological risk in Japan, whereas the construct of independence is more strongly linked with biological risk in the U.S. A final integrative goal is to combine sociodemographic, psychosocial, and reported health assessments to identify (via recursive partitioning) culture-specific pathways to high or low allostatic load (a multi-system indicator of biological risk). Since our prior submission, we have added extensive findings to Preliminary Studies that demonstrate (with pilot data) support for our guiding hypotheses and also document the feasibility of our proposed biological data collection.

我们建议对日本成年人的概率样本进行调查（N = 1,000，除以 性别）30岁至70岁，来自东京都地区。将收集社会人口统计数据 特征（年龄、性别、婚姻状况、教育状况、收入）、社会心理特征（例如， 独立/相互依赖、人格特质、控制感、目标取向、社会支持、家庭 义务、社会责任）、心理健康（抑郁、焦虑、幸福感、生活满意度），以及 身体健康（慢性病、健康症状、功能限制、健康行为）。这些 测量结果与美国中年全国纵向样本（MIDUS）的测量结果相似。这 中心目标是将日本样本 (MIDJA) 与美国样本 (MIDUS) 进行比较，以测试 假设相互依赖的结构可以预测日本的福祉和健康，而 独立的构建预测了美国的福祉和健康状况。我们还预测了美国的年龄差异 健康和福祉，一些表明文化相似性（例如，随着年龄的增长，生活目标逐渐减弱）和 其他表明文化差异（例如，日本在福祉的其他方面的年龄增长更多） 与美国相比）。我们还建议在大约一半的日本调查中收集生物标志物 样本（n = 500）。我们将包括神经内分泌调节、免疫功能和 心血管风险。这些将与正在进行的 MIDUS II P01 项目 4 中的生物学评估并行。 因此，在这两种文化中，我们将研究心理社会因素和生物学之间的联系，以测试 假设相互依赖的结构与日本的生物风险有更紧密的联系， 而在美国，独立性的构建与生物风险的联系更为紧密。 综合目标是将社会人口学、社会心理和报告的健康评估结合起来，以确定 （通过递归划分）文化特定的高或低变稳态负荷途径（多系统指标 生物风险）。自从我们之前提交以来，我们在初步研究中添加了广泛的发现， 证明（通过试点数据）支持我们的指导假设，并记录我们的可行性 提议的生物数据收集。