2013 Phagocytes Gordon Research Conference and Seminar

2013年吞噬细胞戈登研究会议暨研讨会

• 批准号: 8521619
• 负责人: Lee-Ann H Allen
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8521619
• 关键词: Achievement; Alzheimer' s Disease; Arthritis; Atherosclerosis; Biochemistry; Biology; Cardiovascular system; Cell Polarity; Cells; Cellular biology; Clinical; Clinical Medicine; Collaborations; Communication; Communities; Conceptions; Cytoplasmic Granules; Data; Development; Developmental Cell Biology; Diabetes Mellitus; Disabled Persons; Disease; Engineering; Environment; Feedback; Fostering; Functional disorder; Funding; Future; Generations; Genetic; Goals; Growth; Health; Hematology; Homeostasis; Host Defense; Imaging Techniques; Immune response; Immunology; Infection; Infectious Disease Immunology; Inflammation; Inflammatory; Knowledge; Lead; Leukocytes; Location; Lung; Malignant Neoplasms; Medicine; Microbiology; Molecular Genetics; NADPH Oxidase; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Disease; Natural Immunity; Neoplasm Metastasis; New Hampshire; Oral; Pathogenesis; Persons; Phagocytes; Phagosomes; Pharmacology; Physiology; Play; Postdoctoral Fellow; Public Health; Recording of previous events; Regulation; Research; Research Personnel; Research Project Grants; Resort; Role; Running; Scientist; Structure; Students; Time; Tissues; Treatment Protocols; Underrepresented Minority; United States National Institutes of Health; Woman; abstracting; base; combat; design; disability; graduate student; in vivo; lectures; macrophage; meetings; migration; neutrophil; peer; planetary Atmosphere; postdoctoral investigator; posters; programs; public health relevance; skills; symposium; therapeutic target; tool; tumor; vaccinology

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Phagocytes has been in existence since 1981. The 17th GRC on Phagocytes will be held June 9-14, 2013 at Waterville Valley Resort, Waterville Valley, New Hampshire. Although the central role of macrophages and neutrophils in innate immunity has long been recognized, the field continues to evolve. Thus, whereas conferences 20 years ago focused on fundamental aspects of phagocyte structure and function, such as elucidation of the composition of neutrophil granules, and discovery of the NADPH oxidase, the 2013 Phagocytes GRC will be a forum for high-quality presentations and in depth discussions of the most recent discoveries in phagocyte biology, and will highlight the latest advances in our understanding of the phenotypic plasticity o these cells, and their roles in modulation of the adaptive immune response, systemic inflammation and host defense, as well as clinical correlates such as the roles of phagocytes in cancer, arthritis, and Alzheimer's disease, including recently identified therapeutic targets, and the use of phagosomes as tools for vaccinology. Featured technological achievements will include advanced imaging techniques for analysis of neutrophil migration in vivo and reverse engineering intracellular information flow to understand cell polarity. The Conference draws from a world-wide group of scientists with diverse backgrounds in cell biology, biochemistry, molecular genetics, microbiology, immunology and clinical medicine. This meeting has consistently been an important venue for disseminating information and facilitating communication between investigators studying different facets of macrophage and neutrophil function, and also provides a general educational forum for trainees and young investigators. Approximately 150 scientists attended this GRC, and in 2011, ~39% of whom were graduate students or postdoctoral fellows. The program planned for the 2013 GRC includes nine sessions wherein 26 invited speakers will present their latest and most exciting unpublished findings. Each session will be chaired by discussion leaders who are experts in the field. In keeping with tradition, we also plan to select 6-8 junior scientists to present short talks based on submitted abstracts. Each lecture will be followed by ample time for vigorous discussion. In addition to oral presentations, we expect 90 posters to be displayed at the meeting. This multifaceted program will provide opportunities for participation of scientists at all levels and is designed to promote the participation of junior investigators, postdoctoral trainees and new investigators to the field To further promote the participation and professional development of students and postdoctoral fellows, the 2013 Conference will incorporate a Gordon Graduate Research Seminar (GRS) on June 8-9, immediately prior to the start of the GRC, that is organized by trainees. The first two such GRSs were held in association with the 2009 and 2011 Phagocytes GRCs and have been well attended and very well received. We anticipate even greater attendance in 2013.

说明（由申请人提供）： 吞噬细胞戈登研究会议 (GRC) 自 1981 年以来一直存在。第 17 届吞噬细胞 GRC 将于 2013 年 6 月 9 日至 14 日在新罕布什尔州沃特维尔谷的沃特维尔谷度假村举行。尽管巨噬细胞和中性粒细胞在先天免疫中的核心作用早已被认识到，但该领域仍在不断发展。因此，20 年前的会议重点关注吞噬细胞结构和功能的基本方面，例如阐明中性粒细胞颗粒的组成以及 NADPH 氧化酶的发现，而 2013 年吞噬细胞 GRC 将成为一个提供高质量演讲和深入探讨的论坛。讨论吞噬细胞生物学的最新发现，并将重点介绍我们对这些细胞的表型可塑性及其在调节中的作用的理解的最新进展适应性免疫反应、全身炎症和宿主防御的研究，以及临床相关性，例如吞噬细胞在癌症、关节炎和阿尔茨海默氏病中的作用，包括最近确定的治疗靶点，以及吞噬体作为疫苗学工具的用途。特色技术成果将包括用于分析中性粒细胞体内迁移的先进成像技术以及逆向工程细胞内信息流以了解细胞极性。会议由来自世界各地的科学家组成，他们在细胞生物学、生物化学、分子遗传学、微生物学、免疫学和临床医学方面具有不同的背景。这次会议一直是传播信息和促进研究巨噬细胞和中性粒细胞功能不同方面的研究者之间交流的重要场所，也为学员和年轻研究者提供了一个普通教育论坛。大约 150 名科学家参加了这次 GRC，2011 年，其中约 39% 是研究生或博士后。 2013 年 GRC 计划的活动包括九场会议，其中 26 位受邀演讲者将展示他们最新、最令人兴奋的未发表的发现。每场会议将由该领域专家的讨论领袖主持。按照传统，我们还计划根据提交的摘要选拔6-8名青年科学家进行简短的演讲。每场讲座之后都会有充足的时间进行激烈的讨论。除了口头 演示文稿，我们预计会议上将展示 90 张海报。这项多方面的计划将为各级科学家提供参与机会，旨在促进 初级研究员、博士后实习生和新研究员的参与 为了进一步促进学生和博士后研究员的参与和专业发展，2013 年会议将在 6 月 8 日至 9 日举行戈登研究生研究研讨会 (GRS)，紧接会议之前GRC 的开始，由学员组织。前两届 GRS 与 2009 年和 2011 年吞噬细胞 GRC 联合举办，参加人数众多，反响热烈。我们预计 2013 年的出席人数会更多。