HIGH-THROUGHPUT SOLUTION SCATTERING DATA COLLECTION SYSTEM

高通量解决方案散射数据采集系统

• 批准号: 8362096
• 负责人: HIROTSUGU TSURUTA
• 金额: $ 10.97万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362096
• 关键词: Aliquot; Blood capillaries; Cells; Data Collection; Funding; Grant; Liquid substance; National Center for Research Resources; Needles; Principal Investigator; Quartz; Radiation; Research; Research Infrastructure; Resources; Sampling; Solutions; Source; Staging; Syringes; System; Temperature; Translations; United States National Institutes of Health; arm; capillary; cost; instrumentation; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We continue developing the instrumentation for an automated high throughput data collection system for solution x-ray scattering, combining a quartz capillary cell and a motorized sample changer, which comprises a temperature-controlled sample rack in the standard 96-well microplate format and three motorized miniature linear translation stages whose vertical arm holds a syringe needle for sample aliquot selection and delivery. A Hamilton 560 fluid dispenser with two microsyringes and dedicated valves is integrated for pipetting sample aliquots and sending cleaning solutions to the capillary cell.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 我们继续为解决方案X射线散射的自动高吞吐量数据收集系统开发仪器，将石英毛细管电池和电动样品更换器结合在一起，该样品包括标准的96孔微孔格式的温度控制样品架和三种机动化微型线性翻译阶段，其垂直臂固定了一个注射器针，可用于样品等分试样和输送。汉密尔顿560流体分配器，带有两个微纵梁和专用阀门，用于吸管样品等分试样，并将清洁溶液发送到毛细管电池。