MULTIPLEXED BIOSENSOR FOR DETECTING LOW ABUNDANCE CANCER

用于检测低丰度癌症的多重生物传感器

• 批准号: 8356444
• 负责人: KUMAR SUBRAMANIAN
• 金额: $ 19.65万
• 依托单位: PHOENIX BIOSYSTEM, INC.
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-23 至 2012-06-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8356444
• 关键词: Affinity; Biological Assay; Biosensor; Cancer Detection; Cancer Patient; Capital; Cause of Death; Detection; Disease; Enzyme-Linked Immunosorbent Assay; Equipment; Health; Heart Diseases; Individual; Link; Malignant Neoplasms; Marker Discovery; Outcome; Patients; Performance; Proteins; Reagent; Sampling; Specificity; Techniques; Technology; Testing; Training; cross reactivity; improved; miniaturize; novel marker; outcome forecast; prototype; response; tool; usability

Title: Multiplexed Biosensor for Detecting Low Abundance Cancer Description: The proposed automated, miniaturized, highly sensitive, high throughout affinity/protein capture technology could be a powerful tool for the quantitative detection of known cancer protein markers and the discovery of new tumor markers. This biosensor array platform will be easily adaptable to new markers that better detect cancer, estimate patient response to therapies, and improve the prognosis estimate for patients as these markers are discovered and linked to outcomes.

标题：用于检测低丰度癌症的多重生物传感器描述：拟议的自动化，微型化，高度敏感，高度高的亲和力/蛋白质捕获技术可能是定量检测已知癌症蛋白质标记物以及发现新肿瘤标记物的强大工具。该生物传感器阵列平台将很容易适应新标记，这些标记可以更好地检测癌症，估计患者对疗法的反应并改善患者的预后估计，因为这些标记被发现并与结果相关。