IGF::OT::IGFTitle: Multiplexed Biosensor for Detecting Low Abundance Cancer-rel

IGF::OT::IGFTTitle：用于检测低丰度癌症相关的多重生物传感器

• 批准号: 8761949
• 负责人: KUMAR SUBRAMANIAN
• 金额: $ 99.98万
• 依托单位: PHOENIX BIOSYSTEM, INC.
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-25 至 2015-09-24
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8761949
• 关键词: Biological Assay; Biological Markers; Biosensor; Cancer Detection; Cancer Patient; Communities; Disease; Goals; Individual; Malignant Neoplasms; Patients; Protein Analysis; Research; System; Training; design; flexibility; outcome forecast; programs; prototype; sensor; technology development

Phoenix Biosystem has successfully designed, developed and demonstrated the feasibility of a sensitive, versatile, multiplexed biosensor prototype system for protein analysis during PHASE I. The proposed sensor array will support flexible configuration to assay for several tens of biomarkers in a small footpoint. The goal of the proposed PHASE II research will be to expand the assay menu to include additional cancer biomarkers and develop a fully functional, field deployable prototype to complete the technology development to be done in coordination with the CPTC community to integrate the platform into the techology assessment programs and into the greater scientific community.

Phoenix Biosystem 已成功设计、开发并证明了用于第一阶段蛋白质分析的灵敏、多功能、多重生物传感器原型系统的可行性。所提出的传感器阵列将支持灵活的配置，以在小足点内检测数十种生物标志物。拟议的第二阶段研究的目标将是扩展检测菜单，以包括其他癌症生物标志物，并开发功能齐全、可现场部署的原型，以完成与 CPTC 社区协调进行的技术开发，将该平台集成到技术中评估计划并进入更大的科学界。