DELINEATION OF MULTIPLE SUBPOPULATIONS OF NATURAL KILLER CELLS IN MONKEYS

猴子自然杀伤细胞多个亚群的划分

• 批准号: 8357919
• 负责人: R. PAUL JOHNSON
• 金额: $ 19.39万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357919
• 关键词: Animals; Funding; Grant; Homing; Infection; Manuscripts; Monkeys; National Center for Research Resources; Natural Killer Cells; New England; Primates; Principal Investigator; Publishing; Research; Research Infrastructure; Resources; SIV; Source; United States National Institutes of Health; base; cost; cytotoxic; lymph nodes

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Over the last year we completed our analyses of changes in NK cells in SIV-infected animals and published two manuscripts. These results show that SIV infection upregulates cytotoxic activity of NK cells and shifts homing from lymph nodes to the gut.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 在过去的一年中，我们完成了对SIV感染动物NK细胞变化的分析，并发表了两个手稿。 这些结果表明，SIV感染上调了NK细胞的细胞毒性活性，并将其从淋巴结转移到肠道。