MODULATION OF PD-1 EXPRESSION ON T CELLS IN SIV-INFECTED MACAQUES

SIV 感染的猕猴 T 细胞上 PD-1 表达的调节

• 批准号: 8357947
• 负责人: R. PAUL JOHNSON
• 金额: $ 19.54万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357947
• 关键词: CD8B1 gene; Funding; Gene Expression; Grant; Macaca; National Center for Research Resources; New England; Pattern; Primates; Principal Investigator; Research; Research Infrastructure; Resources; SIV; Source; T-Lymphocyte; United States National Institutes of Health; base; cost; exhaust; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Experiments over the last year have focused on developing a more precise phenotypic definition of exhausted T cells and characterizing patterns of gene expression in PD-1+ CD8+ T cells.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 去年的实验集中在开发耗尽的T细胞的更精确的表型定义，并表征PD-1+ CD8+ T细胞中基因表达的模式。