Biostatistics and Data Management

生物统计学和数据管理

• 批准号: 8330917
• 负责人: Heidi L Weiss
• 金额: $ 11.84万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8330917
• 关键词: Animal Experiments; Biometry; Biostatistics Core; Biostatistics Shared Resource; Cancer Center; Clinical; Clinical Research; Clinical Trials; Collaborations; Conduct Clinical Trials; Consultations; Data; Data Analyses; Development Plans; Ensure; Human Resources; Laboratories; Lymphoma; Medicine; Monitor; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Safety; Statistical Data Interpretation; System; Toxic effect; Validation; college; data management; experience; innovation; member; pre-clinical; programs; research study; sound; translational study

The Biostatistics Core for the Baylor College of Medicine's Lymphoma SPORE will provide comprehensive and centralized support that integrates the biostatistical activities of the research projects in this SPORE program. The specific aims of this core are to: 1. coordinate and manage the statistical activities of the SPOREto ensure that investigators have ready access to biostatistical consultation; 2. provide biostatistical expertise in study planning and conduct of clinical trials and preclinical validation experiments; 3. coordinate data management activities in close collaborationwith the Clinical Core; and 4. provide comprehensive support for data analysis including safety/toxicity monitoring, interim reviews of data, final analysis, and reporting. This Lymphoma SPORE application proposes iterative laboratory-clinical studies which entails scientific and statistical input for the ensuing animal experiments and clinical trials. The Biostatistics Core personnel will incorporate sound experimental principles in study planning and development, implement a coordinated data management system, and facilitate provision of timely and high-quality statistical analysis and data interpretation. The Biostatistics Core of this SPORE application will draw support from existing members of Baylor Cancer Center's Biostatistics Shared Resource who are highly experienced and have established collaborations with the research members of this SPORE. Ultimately, the SPORE investigators in this application will benefit from the infrastructure of the Biostatistics Core to ensure the implementation of innovative and high-quality translational studies.

贝勒医学院淋巴瘤孢子的生物统计学核心将提供全面的 和集中的支持，将研究项目的生物统计活动整合到该孢子中 程序。 该核心的具体目的是： 1。协调和管理Sporeto的统计活动，确保调查人员拥有 可以访问生物统计咨询； 2。在研究计划和进行临床试验和临床前的研究计划和行为方面提供生物统计学专业知识 验证实验； 3。与临床核心密切合作协调数据管理活动；和 4。为数据分析提供全面的支持，包括安全/毒性监测，临时 综述数据，最终分析和报告。 这种淋巴瘤孢子应用提出了迭代实验室临床研究，该研究需要科学和 随后的动物实验和临床试验的统计输入。生物统计学核心人员将 将声音实验原理纳入研究计划和开发，实施协调数据 管理系统，并促进及时和高质量的统计分析和数据提供 解释。该孢子应用程序的生物统计学核心将获得 贝勒癌症中心的生物统计学共享资源，他们经验丰富且已建立 与该孢子的研究成员合作。最终，孢子调查人员 应用将受益于生物统计学核心的基础设施，以确保实施 创新和高质量的翻译研究。